Cas no 1759-35-9 (4-Nor-3,5-seco-5-oxo-17β-hydroxyandrostan-3-oic Acid)

4-Nor-3,5-seco-5-oxo-17β-hydroxyandrostan-3-oic Acid is a steroidal derivative characterized by its unique structural modifications, including the absence of the C4 methyl group (4-nor) and the cleavage of the 3,5-seco ring system with a 5-oxo functionality. The 17β-hydroxy group and 3-oic acid moiety enhance its polarity, making it a valuable intermediate in synthetic organic chemistry and steroid research. Its distinct framework allows for further functionalization, enabling the development of novel bioactive compounds. This compound is particularly useful in studying structure-activity relationships in steroid-based pharmaceuticals due to its modified backbone, which influences receptor binding and metabolic stability.
4-Nor-3,5-seco-5-oxo-17β-hydroxyandrostan-3-oic Acid structure
1759-35-9 structure
Product Name:4-Nor-3,5-seco-5-oxo-17β-hydroxyandrostan-3-oic Acid
CAS No:1759-35-9
MF:C18H28O4
MW:308.412526130676
CID:1015211
Update Time:2025-05-21

4-Nor-3,5-seco-5-oxo-17β-hydroxyandrostan-3-oic Acid Chemical and Physical Properties

Names and Identifiers

    • 3,5-Seco-A-norandrostan-17β-ol-5-on-3-oic Acid
    • (3S,3aS,5aS,6R,9aS,9bS)-Dodecahydro-3-hydroxy-3a,6-diMethyl-7-oxo-1H-benz[e]indene-6-propanoic Acid
    • [3S-(3α,3aα,5aβ,6β,9aα,9bβ)]-Dodecahydro-3-hydroxy-3a,6-diMethyl-7-oxo-1H-benz[e]indene-6-propanoic Acid
    • 17β-Hydroxy-5-oxo-A-nor-3,5-secoandrostan-3-oic Acid
    • 4-Nor-3,5-seco-5-oxo-17β-hydroxyandrostan-3-oic Acid
    • 3-[(3S,3aS,5aS,6R,9aS,9bS)-3-hydroxy-3a,6-dimethyl-7-oxo-1,2,3,4,5,5a,8,9,9a,9b-decahydrocyclopenta[a]naphthalen-6-yl]propanoic acid
    • 3,5-Seco-A-norandrostan-17
    • 4-Nor-3,5-seco-5-oxo-17
    • A-Hydroxy-5-oxo-A-nor-3,5-secoandrostan-3-oic Acid
    • A-hydroxyandrostan-3-oic Acid
    • A-ol-5-on-3-oic Acid
    • Inchi: 1S/C18H28O4/c1-17-9-7-13-11(12(17)4-6-15(17)20)3-5-14(19)18(13,2)10-8-16(21)22/h11-13,15,20H,3-10H2,1-2H3,(H,21,22)/t11-,12-,13-,15-,17-,18+/m0/s1
    • InChI Key: COGRAKQBTBRYQC-HHJOSPGFSA-N
    • SMILES: O[C@H]1CC[C@H]2[C@@H]3CCC([C@](C)(CCC(=O)O)[C@H]3CC[C@@]21C)=O

Computed Properties

  • Exact Mass: 308.19900

Experimental Properties

  • PSA: 74.60000
  • LogP: 3.02380

4-Nor-3,5-seco-5-oxo-17β-hydroxyandrostan-3-oic Acid Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
TRC
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4-Nor-3,5-seco-5-oxo-17β-hydroxyandrostan-3-oic Acid
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Additional information on 4-Nor-3,5-seco-5-oxo-17β-hydroxyandrostan-3-oic Acid

Professional Introduction to 4-Nor-3,5-seco-5-oxo-17β-hydroxyandrostan-3-oic Acid (CAS No. 1759-35-9)

4-Nor-3,5-seco-5-oxo-17??-hydroxyandrostan-3-oic Acid, identified by its CAS number 1759-35-9, is a significant compound in the field of biochemistry and pharmaceutical research. This compound belongs to the class of androgenic steroids, which have garnered considerable attention due to their diverse biological activities and potential therapeutic applications. The molecular structure of 4-Nor-3,5-seco-5-oxo-17β-hydroxyandrostan-3-oic Acid features a complex arrangement of functional groups, making it a valuable subject for detailed study and innovation in medicinal chemistry.

The chemical formula of this compound is C19H24O4, reflecting its composition of carbon, hydrogen, and oxygen atoms arranged in a specific configuration. The presence of hydroxyl and carboxyl groups in its structure contributes to its reactivity and interaction with biological targets. This molecular complexity has positioned 4-Nor-3,5-seco-5-oxo-17β-hydroxyandrostan-3-oic Acid as a key intermediate in the synthesis of more complex steroid derivatives, which are being explored for their pharmacological properties.

In recent years, research on steroids has seen significant advancements, particularly in understanding their role in endocrine regulation and disease mechanisms. The study of 4-Nor-3,5-seco-5-oxo-17β-hydroxyandrostan-3-oic Acid has provided insights into the structural and functional aspects of androgen receptors, which are crucial for developing treatments related to hormonal imbalances and related disorders. The compound's ability to modulate these receptors has made it a subject of interest in the development of novel therapeutics for conditions such as testosterone replacement therapy and prostate health.

The synthesis of 4-Nor-3,5-seco-5-oxo-17β-hydroxyandrostan-3-oic Acid involves multi-step organic reactions that require precise control over reaction conditions and reagent selection. Advanced synthetic methodologies have been employed to optimize yield and purity, ensuring that the final product meets the stringent standards required for pharmaceutical applications. Techniques such as chromatography and spectroscopic analysis play a crucial role in characterizing the compound's structure and verifying its identity.

One of the most compelling aspects of studying 4-Nor-3,5-seco-5-oxo-17β-hydroxyandrostan-3-oic Acid is its potential as a precursor for more complex steroid molecules. Researchers have leveraged its structural framework to develop derivatives with enhanced pharmacological activity. For instance, modifications at the 17β-hydroxyl group have been explored to improve metabolic stability and bioavailability. These efforts align with the broader goal of creating more effective and targeted therapies that minimize side effects while maximizing therapeutic benefits.

The biological activity of 4-Nor-3,5-seco-5-oxo-17β-hydroxyandrostan-3-oic Acid has been investigated in various preclinical models. Studies have demonstrated its potential role in modulating pathways associated with inflammation, metabolism, and cellular growth. These findings have prompted further exploration into its therapeutic applications, particularly in areas where hormonal regulation is a key factor. The compound's interactions with enzymes and receptors have been extensively studied to understand how it exerts its effects at the molecular level.

The latest research trends indicate that steroids like 4-Nor-3,5-seco-5-oxo-17β-hydroxyandrostan-3-oic Acid are being increasingly utilized in combination therapies to address complex diseases. The synergistic effects observed when these compounds are used alongside other pharmacological agents highlight their potential as part of multifaceted treatment strategies. This approach is particularly relevant in managing chronic conditions where long-term efficacy and minimal side effects are critical considerations.

In conclusion, 4-Nor-3,5-seco-5 oxo - 17β hydroxyandrostan - 3 - oic Acid (CAS No. 1759 - 35 - 9) represents a significant advancement in steroid chemistry with promising implications for pharmaceutical development. Its complex structure, versatile reactivity, and biological activity make it a valuable tool for researchers seeking to develop novel therapeutics. As our understanding of steroid mechanisms continues to evolve, compounds like this will undoubtedly play a pivotal role in shaping the future of medicine.

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