Cas no 174518-82-2 (1-Bromo-2,5-dimethoxy-4-iodobenzene)

1-Bromo-2,5-dimethoxy-4-iodobenzene is a halogenated aromatic compound featuring bromine and iodine substituents on a dimethoxybenzene scaffold. Its distinct substitution pattern makes it a valuable intermediate in organic synthesis, particularly in the preparation of complex molecules for pharmaceuticals, agrochemicals, and materials science. The presence of both bromine and iodine offers versatile reactivity for further functionalization via cross-coupling reactions, such as Suzuki or Sonogashira couplings. The dimethoxy groups enhance solubility in organic solvents, facilitating handling in synthetic workflows. This compound is particularly useful in medicinal chemistry for constructing pharmacophores or as a precursor in the development of advanced materials. High purity grades ensure consistent performance in demanding applications.

1-Bromo-2,5-dimethoxy-4-iodobenzene structure

174518-82-2 structure

Product Name:1-Bromo-2,5-dimethoxy-4-iodobenzene

CAS No:174518-82-2

MF:C₈H₈BrIO₂

MW:342.956394195557

MDL:MFCD27665621

CID:1360110

PubChem ID:639172

Update Time:2025-06-14

1-Bromo-2,5-dimethoxy-4-iodobenzene Chemical and Physical Properties

Names and Identifiers

- Benzene, 1-bromo-4-iodo-2,5-dimethoxy-
- 1-bromo-4-iodo-2,5-dimethoxybenzene
- 1-Bromo-2,5-dimethoxy-4-iodobenzene
- 1,4-Dimethoxy-2-iodo-5-bromobenzene
- AK264609
- InChI=1/C8H8BrIO2/c1-11-7-4-6(10)8(12-2)3-5(7)9/h3-4H,1-2H
- ZGA51882
- SY316736
- 174518-82-2
- DS-10907
- MFCD27665621
- CS-0098756
- AKOS027292465
- S11227
- MDL： MFCD27665621
- Inchi： 1S/C8H8BrIO2/c1-11-7-4-6(10)8(12-2)3-5(7)9/h3-4H,1-2H3
- InChI Key： HNPIBZGULNUJST-UHFFFAOYSA-N
- SMILES： IC1C=C(C(=CC=1OC)Br)OC

Computed Properties

Exact Mass: 341.87474
Monoisotopic Mass: 341.87524g/mol
Isotope Atom Count: 0
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 2
Heavy Atom Count: 12
Rotatable Bond Count: 2
Complexity: 145
Covalently-Bonded Unit Count: 1
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count : 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
XLogP3: 3.5
Topological Polar Surface Area: 18.5

Experimental Properties

PSA: 18.46

1-Bromo-2,5-dimethoxy-4-iodobenzene Pricemore >>

Related Categories	No.	Product Name	Cas No.	Purity	Specification	Price	update time
SHANG HAI XIAN DING Biotechnology Co., Ltd.	B-YI792-5g	1-Bromo-2,5-dimethoxy-4-iodobenzene	174518-82-2	95+%	5g	1869.0CNY	2021-07-12
SHANG HAI XIAN DING Biotechnology Co., Ltd.	B-YI792-1g	1-Bromo-2,5-dimethoxy-4-iodobenzene	174518-82-2	95+%	1g	575.0CNY	2021-07-12
SHANG HAI XIAN DING Biotechnology Co., Ltd.	B-YI792-50mg	1-Bromo-2,5-dimethoxy-4-iodobenzene	174518-82-2	95+%	50mg	82.0CNY	2021-07-12
SHANG HAI XIAN DING Biotechnology Co., Ltd.	B-YI792-250mg	1-Bromo-2,5-dimethoxy-4-iodobenzene	174518-82-2	95+%	250mg	288CNY	2021-05-08
Alichem	A019087687-5g	1-Bromo-2,5-dimethoxy-4-iodobenzene	174518-82-2	95%	5g	216.30 USD	2021-06-17
Alichem	A019087687-10g	1-Bromo-2,5-dimethoxy-4-iodobenzene	174518-82-2	95%	10g	339.50 USD	2021-06-17
Alichem	A019087687-25g	1-Bromo-2,5-dimethoxy-4-iodobenzene	174518-82-2	95%	25g	707.20 USD	2021-06-17
Chemenu	CM250329-5g	1-Bromo-2,5-dimethoxy-4-iodobenzene	174518-82-2	95%	5g	$246	2025-07-04
Chemenu	CM250329-10g	1-Bromo-2,5-dimethoxy-4-iodobenzene	174518-82-2	95%	10g	$411	2025-07-04
Chemenu	CM250329-25g	1-Bromo-2,5-dimethoxy-4-iodobenzene	174518-82-2	95%	25g	$799	2025-07-04

1-Bromo-2,5-dimethoxy-4-iodobenzene Suppliers

Suzhou Senfeida Chemical Co., Ltd

Gold Member

Audited Supplier

(CAS:174518-82-2)1-Bromo-4-iodo-2,5-dimethoxybenzene

Order Number:sfd5348

Stock Status:in Stock

Quantity:200kg

Purity:99.9%

Pricing Information Last Updated:Friday, 19 July 2024 14:33

Price ($):discuss personally

Email:[email protected]

Product Official Link

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Additional information on 1-Bromo-2,5-dimethoxy-4-iodobenzene

Comprehensive Overview of 1-Bromo-2,5-dimethoxy-4-iodobenzene (CAS No. 174518-82-2): Properties, Applications, and Industry Insights

1-Bromo-2,5-dimethoxy-4-iodobenzene (CAS No. 174518-82-2) is a halogenated aromatic compound with significant relevance in organic synthesis and pharmaceutical research. Its unique structure, featuring bromo, iodo, and methoxy functional groups, makes it a versatile intermediate for constructing complex molecules. Researchers and industries value this compound for its role in cross-coupling reactions, particularly in Suzuki-Miyaura and Ullmann-type transformations, which are pivotal in drug discovery and material science.

The growing demand for halogenated benzene derivatives like 1-Bromo-2,5-dimethoxy-4-iodobenzene is driven by advancements in catalysis and green chemistry. Recent trends highlight its utility in developing OLED materials and agrochemicals, aligning with the global push for sustainable technologies. A frequent query among chemists is: "How does the electronic effect of methoxy groups influence the reactivity of this compound?" Studies suggest that the electron-donating nature of dimethoxy substituents enhances the stability of intermediates in nucleophilic substitutions.

From a synthetic perspective, CAS 174518-82-2 is often employed to introduce aryl halide motifs into larger frameworks. Its iodo and bromo groups allow selective functionalization, a feature exploited in multistep synthesis workflows. Industry reports emphasize its use in API (Active Pharmaceutical Ingredient) production, where precision in halogen placement is critical for bioactivity. Notably, its compatibility with microwave-assisted synthesis has reduced reaction times, addressing efficiency concerns in R&D pipelines.

Environmental and safety considerations are also paramount. While not classified as hazardous under standard protocols, proper handling of 1-Bromo-2,5-dimethoxy-4-iodobenzene requires adherence to GLP (Good Laboratory Practice). FAQs often revolve around storage conditions—recommendations include inert atmospheres and protection from light to prevent degradation of its halogen bonds.

In summary, 1-Bromo-2,5-dimethoxy-4-iodobenzene (CAS 174518-82-2) bridges academic research and industrial applications, offering a robust platform for innovation in heterocyclic chemistry and beyond. Its adaptability to modern synthetic methodologies ensures its continued prominence in scientific literature and patent filings.

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