Cas no 174125-30-5 (Silane,(5-chloro-1-pentyn-1-yl)triethyl-)

Silane, (5-chloro-1-pentyn-1-yl)triethyl-, is a specialized organosilicon compound featuring a terminal alkyne group and a chloroalkyl substituent. This structure enables its use as a versatile intermediate in organic synthesis, particularly in click chemistry applications such as copper-catalyzed azide-alkyne cycloaddition (CuAAC). The triethylsilane moiety enhances stability and reactivity, while the chloroalkyl group allows for further functionalization. Its well-defined reactivity profile makes it suitable for surface modification, polymer chemistry, and the development of advanced materials. The compound is typically handled under inert conditions due to its sensitivity to moisture and air. Proper storage and handling are essential to maintain its integrity for synthetic applications.
Silane,(5-chloro-1-pentyn-1-yl)triethyl- structure
174125-30-5 structure
Product Name:Silane,(5-chloro-1-pentyn-1-yl)triethyl-
CAS No:174125-30-5
MF:C11H21ClSi
MW:216.82294344902
MDL:MFCD00671352
CID:137735
PubChem ID:2757930
Update Time:2025-10-19

Silane,(5-chloro-1-pentyn-1-yl)triethyl- Chemical and Physical Properties

Names and Identifiers

    • Silane,(5-chloro-1-pentyn-1-yl)triethyl-
    • 1-Chloro-5-Triethylsilyl-4-Pentyne
    • 5-chloropent-1-ynyl(triethyl)silane
    • TRIETHYLSILYL-5-CHLOROPENTYNE
    • AKOS015911289
    • (5-Chloropent-1-yn-1-yl)(triethyl)silane
    • AS-75541
    • MFCD00671352
    • CS-0336845
    • (5-Chloropent-1-ynyl)triethylsilane
    • A811616
    • DTXSID40374075
    • (5-chloropent-1-yn-1-yl)triethylsilane
    • S04790
    • Silane, (5-chloro-1-pentyn-1-yl)triethyl-
    • 174125-30-5
    • MDL: MFCD00671352
    • Inchi: 1S/C11H21ClSi/c1-4-13(5-2,6-3)11-9-7-8-10-12/h4-8,10H2,1-3H3
    • InChI Key: YOFYXFCOGXKCGG-UHFFFAOYSA-N
    • SMILES: ClCCCC#C[Si](CC)(CC)CC

Computed Properties

  • Exact Mass: 216.11000
  • Monoisotopic Mass: 216.11
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 0
  • Heavy Atom Count: 13
  • Rotatable Bond Count: 5
  • Complexity: 175
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 0A^2

Experimental Properties

  • Density: 0.903?g/mL?at 25?°C(lit.)
  • Boiling Point: 244-245?°C
  • Flash Point: 215?°F
  • Refractive Index: n20/D 1.468(lit.)
  • PSA: 0.00000
  • LogP: 4.05650

Silane,(5-chloro-1-pentyn-1-yl)triethyl- Security Information

  • WGK Germany:3
  • Hazard Category Code: 36/37/38
  • Safety Instruction: S26; S36
  • Hazardous Material Identification: Xi
  • Risk Phrases:R36/37/38
  • Safety Term:S26-36

Silane,(5-chloro-1-pentyn-1-yl)triethyl- Pricemore >>

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Additional information on Silane,(5-chloro-1-pentyn-1-yl)triethyl-

Introduction to Silane, (5-chloro-1-pentyn-1-yl)triethyl

Compound with the CAS number 174125-30-5 is a specialized organosilicon compound known as Silane, (5-chloro-1-pentyn-1-yl)triethyl. This compound has garnered significant attention in the field of chemical and pharmaceutical research due to its unique structural properties and potential applications. Silanes are a class of organosilicon compounds that feature a silicon atom bonded to three alkyl or aryl groups, along with one or more hydroxyl groups. The specific structure of Silane, (5-chloro-1-pentyn-1-yl)triethyl makes it a versatile intermediate in organic synthesis, particularly in the development of novel materials and pharmaceuticals.

The molecular formula of this compound can be represented as C10H17ClSi. The presence of a triple bond in the pentynyl group and a chlorine substituent introduces reactivity that can be exploited in various synthetic pathways. This compound is particularly interesting because it combines the reactivity of alkyne groups with the stability of silicon-based structures, making it a valuable building block in synthetic chemistry.

In recent years, there has been a growing interest in organosilicon compounds for their applications in pharmaceuticals, agrochemicals, and materials science. The ability of silanes to undergo various reactions such as hydrosilylation, cross-coupling, and polymerization makes them indispensable tools in synthetic organic chemistry. Specifically, Silane, (5-chloro-1-pentyn-1-yl)triethyl has been explored for its potential in the synthesis of complex organic molecules, including those with therapeutic properties.

One of the most notable applications of this compound is in the field of drug discovery. The unique reactivity of the alkyne group allows for the introduction of functionalized side chains that can interact with biological targets. For instance, researchers have utilized derivatives of this silane to develop novel inhibitors targeting enzymes involved in diseases such as cancer and inflammation. The chlorine substituent also provides a handle for further functionalization through nucleophilic substitution reactions, enabling the creation of diverse pharmacophores.

The synthesis of Silane, (5-chloro-1-pentyn-1-yl)triethyl typically involves the reaction of 5-chloropentyne with triethylsilanol or a similar reagent under controlled conditions. Advanced techniques such as transition metal catalysis have been employed to optimize yield and purity. These synthetic methods are critical for ensuring that the final product meets the stringent requirements for use in pharmaceutical applications.

In addition to its pharmaceutical applications, this compound has shown promise in materials science. Silanes are known for their ability to modify surface properties of materials, making them useful in coatings, adhesives, and nanotechnology. The specific structure of Silane, (5-chloro-1-pentyn-1-yl)triethyl allows it to form stable bonds with various substrates, enhancing material performance. For example, it has been used to create self-assembling monolayers on metal surfaces, which can serve as templates for further functionalization.

The latest research on this compound has focused on its role in polymer chemistry. Silanes can act as crosslinking agents or monomers in polymer synthesis, leading to materials with enhanced mechanical and thermal properties. The triple bond in the pentynyl group provides a site for polymerization reactions, while the ethyl groups contribute to flexibility and processability. This has led to the development of novel polymers that could find applications in aerospace, automotive industries, and electronics.

Economic considerations also play a significant role in the adoption of Silane, (5-chloro-1-pentyn-1-yl)triethyl. As demand for high-performance materials and pharmaceuticals grows, so does the need for efficient synthetic routes and cost-effective production methods. Researchers are continually exploring ways to optimize processes and reduce costs without compromising quality. This includes developing greener synthetic methods that minimize waste and energy consumption.

The future prospects for this compound are promising. As our understanding of its reactivity and potential applications deepens, new uses are likely to emerge. Advances in computational chemistry and machine learning are also expected to accelerate the discovery and optimization of new silane-based compounds. These technologies can help predict properties and reactivity patterns more accurately than traditional methods alone.

In conclusion, Silane, (5-chloro-1-pentyn-1-yl)triethyl, with its CAS number 174125-30-5, represents an exciting area of research with significant implications across multiple industries. Its unique structural features make it a valuable tool for synthetic chemists working on pharmaceuticals and advanced materials. As research continues to uncover new possibilities for this compound, its importance is likely to grow even further.

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