Cas no 17298-37-2 (Propionyl-L-carnitine)

Propionyl-L-carnitine (PLC) is a naturally occurring derivative of L-carnitine, distinguished by the addition of a propionyl group to its molecular structure. This modification enhances its role in cellular energy metabolism, particularly in facilitating the transport of fatty acids into mitochondria for β-oxidation. PLC also exhibits superior solubility and bioavailability compared to standard L-carnitine, making it more effective in supporting metabolic processes. Clinically, it has been studied for its potential benefits in cardiovascular health, peripheral vascular function, and metabolic disorders due to its vasodilatory and antioxidant properties. Its biochemical stability and targeted action make it a valuable compound in both research and therapeutic applications.
Propionyl-L-carnitine structure
Propionyl-L-carnitine structure
Product Name:Propionyl-L-carnitine
CAS No:17298-37-2
MF:C10H19NO4
MW:217.26216340065
CID:152718
PubChem ID:107738
Update Time:2025-05-22

Propionyl-L-carnitine Chemical and Physical Properties

Names and Identifiers

    • Propionyl-L-carnitine
    • (±)-Propionylcarnitine chloride
    • BRN 1753748
    • EINECS 226-571-8
    • N-(aminocarbonyl)-propanamide
    • N-(Aminocarbonyl)propanamide
    • n-Propinylharnstoff
    • N-Propionylharnstoff
    • n-Propionylurea
    • NSC14270
    • O-Propionyl-carnitin
    • Propanamide, N-(aminocarbonyl)-
    • Propionsaeure-ureid
    • propionyl L(-)carnitine
    • propionyl l-carnitine
    • Propionylharnstoff
    • Propionyl-harnstoff
    • propionyl-urea
    • Propionylurea
    • Urea, propionyl-
    • Hsdb 7589
    • Propionyl Carnitine
    • (+/-)-PROPIONYLCARNITINE CHLORIDE
    • 3-propanoyloxy-4-trimethylammonio-butanoate
    • 3-Carboxy-N,N,N-trimethyl-2-(1-oxopropoxy)-1-propanaminium inner salt
    • 1-Propanaminium, 3-carboxy-N,N,N-trimethyl-2-(1-oxopropoxy)-, inner salt
    • Propionylcarnitine
    • Propionyl-Carnitine
    • HY-113092
    • CHEBI:28867
    • Q27103933
    • 3-(propanoyloxy)-4-(trimethylazaniumyl)butanoate
    • O-Propionylcarnitine
    • AKOS030540155
    • O-propanoylcarnitine (internal charge)
    • LMFA07070105
    • 17298-37-2
    • DTXSID20938255
    • CS-0059547
    • Acylcarnitine C3:0
    • 3-propanoyloxy-4-(trimethylazaniumyl)butanoate
    • SCHEMBL156850
    • NS00015030
    • 3-(propionyloxy)-4-(trimethylammonio)butanoate
    • (3-Carboxy-2-propanoyloxypropyl)-trimethylazanium
    • C03017
    • CHEMBL2074916
    • Inchi: 1S/C10H19NO4/c1-5-10(14)15-8(6-9(12)13)7-11(2,3)4/h8H,5-7H2,1-4H3
    • InChI Key: UFAHZIUFPNSHSL-UHFFFAOYSA-N
    • SMILES: O(C(CC)=O)C(CC(=O)[O-])C[N+](C)(C)C

Computed Properties

  • Exact Mass: 217.13147
  • Monoisotopic Mass: 217.13140809g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 15
  • Rotatable Bond Count: 6
  • Complexity: 227
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 1
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 0.9
  • Topological Polar Surface Area: 66.4?2

Experimental Properties

  • PSA: 66.43

Propionyl-L-carnitine Security Information

  • Storage Condition:Powder -20°C 3 years In solvent -80°C 6 months ? -20°C 1 month

Propionyl-L-carnitine Pricemore >>

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Additional information on Propionyl-L-carnitine

Comprehensive Guide to Propionyl-L-carnitine (CAS No. 17298-37-2): Benefits, Mechanisms, and Applications

Propionyl-L-carnitine (PLC), with the CAS number 17298-37-2, is a naturally occurring derivative of L-carnitine, a compound essential for energy metabolism. This modified form combines L-carnitine with a propionyl group, enhancing its bioavailability and therapeutic potential. PLC has gained significant attention in recent years due to its role in cardiovascular health, metabolic support, and athletic performance. Researchers and health enthusiasts alike are increasingly searching for terms like "Propionyl-L-carnitine benefits," "PLC for heart health," and "17298-37-2 supplement uses," reflecting growing interest in its applications.

The primary mechanism of Propionyl-L-carnitine revolves around its ability to optimize fatty acid oxidation, particularly in tissues with high energy demands, such as the heart and skeletal muscles. Unlike standard L-carnitine, PLC’s propionyl moiety provides additional metabolic flexibility, making it a preferred choice for conditions like peripheral artery disease (PAD) and chronic fatigue. Recent studies highlight its potential to improve endothelial function, a hot topic in cardiovascular research, as users frequently search for "natural ways to boost circulation" and "PLC for vascular health."

In the realm of sports nutrition, Propionyl-L-carnitine is often compared to other performance enhancers like creatine or beta-alanine. Searches for "PLC vs. L-carnitine for endurance" or "best carnitine form for athletes" underscore its relevance. PLC’s dual action—supporting energy production while reducing oxidative stress—makes it a standout ingredient in pre-workout formulas. Additionally, its neuroprotective properties are gaining traction, with queries like "PLC for cognitive function" emerging in nootropic discussions.

From a biochemical perspective, the CAS no. 17298-37-2 identifies Propionyl-L-carnitine as a distinct entity with unique pharmacokinetics. Its molecular structure allows for efficient cellular uptake, a feature often explored in peer-reviewed journals. This specificity aligns with the rise in "targeted nutrient delivery" as a wellness trend. Furthermore, PLC’s synergy with antioxidants like coenzyme Q10 is frequently cited, addressing search trends such as "combining PLC with CoQ10."

Quality and sourcing are critical for Propionyl-L-carnitine efficacy. Consumers increasingly seek "PLC purity standards" and "17298-37-2 testing methods," emphasizing the need for transparency in nutraceutical manufacturing. Regulatory-compliant production ensures optimal potency, a point of interest for professionals navigating "clinical-grade PLC supplements." As research evolves, PLC’s applications in age-related metabolic decline and insulin sensitivity continue to expand, cementing its status as a multifaceted therapeutic agent.

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