Cas no 17210-51-4 (Guvacoline Hydrobromide)

Guvacoline Hydrobromide is a quaternary ammonium alkaloid derived from the Areca nut, primarily used in pharmacological and biochemical research. Its hydrobromide salt form enhances solubility and stability, making it suitable for experimental applications. The compound acts as a cholinergic agonist, specifically targeting muscarinic and nicotinic receptors, which is valuable for studying neurotransmitter pathways and receptor interactions. Its well-defined chemical structure and high purity ensure reproducibility in research settings. Guvacoline Hydrobromide is particularly useful in neuropharmacology for investigating parasympathetic nervous system effects and potential therapeutic applications. Proper handling and storage are recommended to maintain its integrity.
Guvacoline Hydrobromide structure
Guvacoline Hydrobromide structure
Product Name:Guvacoline Hydrobromide
CAS No:17210-51-4
MF:C7H12BrNO2
MW:222.079681396484
CID:905613
PubChem ID:15560296
Update Time:2025-05-22

Guvacoline Hydrobromide Chemical and Physical Properties

Names and Identifiers

    • Guvacoline Hydrobromide
    • methyl 1,2,3,6-tetrahydropyridine-5-carboxylate,hydrobromide
    • 1,2,5,6-Tetrahydro-3-pyridinecarboxylic Acid Methyl Ester HydrobroMide
    • 1,2,5,6-tetrahydro-3-pyridinecarboxylic acid, methyl ester, monohydrobromide
    • Guvacoline (hydrobromide?)
    • DTXSID20574157
    • CS-0065632
    • J-010795
    • Methyl 1,2,5,6-tetrahydropyridine-3-carboxylate--hydrogen bromide (1/1)
    • Guvacoline (hydrobromide)
    • HY-116490
    • DOXOETUWVNVADB-UHFFFAOYSA-N
    • METHYL 1,2,5,6-TETRAHYDROPYRIDINE-3-CARBOXYLATE HYDROBROMIDE
    • 1,2,5,6-tetrahydropyridine-3-carboxylic acid methyl ester hydrobromide
    • Guvacoline, Hydrobromide
    • 17210-51-4
    • SCHEMBL8872254
    • methyl 1,2,3,6-tetrahydropyridine-5-carboxylate;hydrobromide
    • Guvacine methyl ester,hydrobromide
    • 1,2,5,6-Tetrahydronicotinic Acid Methyl Ester Hydrobromide
    • DA-63972
    • Inchi: 1S/C7H11NO2.BrH/c1-10-7(9)6-3-2-4-8-5-6;/h3,8H,2,4-5H2,1H3;1H
    • InChI Key: DOXOETUWVNVADB-UHFFFAOYSA-N
    • SMILES: Br.O(C)C(C1=CCCNC1)=O

Computed Properties

  • Exact Mass: 221.00500
  • Monoisotopic Mass: 221.00514g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 2
  • Complexity: 163
  • Covalently-Bonded Unit Count: 2
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 38.3?2

Experimental Properties

  • Melting Point: 144°C
  • Solubility: Chloroform (Slightly), Methanol (Slightly), Water (Slightly)
  • PSA: 38.33000
  • LogP: 1.36600

Guvacoline Hydrobromide Security Information

Guvacoline Hydrobromide Pricemore >>

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Guvacoline Hydrobromide Production Method

Additional information on Guvacoline Hydrobromide

Guvacoline Hydrobromide: A Comprehensive Overview

Guvacoline Hydrobromide, also known by its CAS number 17210-51-4, is a compound that has garnered significant attention in the scientific and pharmaceutical communities. This compound is primarily recognized for its role in various pharmacological applications, particularly in the field of neuroscience. The name Guvacoline Hydrobromide itself suggests its chemical composition, with "hydrobromide" indicating the presence of a bromine atom in its structure.

Recent studies have highlighted the potential of Guvacoline Hydrobromide as a promising agent in the treatment of neurological disorders. Researchers have explored its ability to modulate neurotransmitter systems, particularly dopamine and serotonin pathways, which are crucial for regulating mood, cognition, and motor functions. This modulation has shown potential benefits in conditions such as depression, anxiety, and Parkinson's disease.

The chemical structure of CAS 17210-51-4 plays a pivotal role in its pharmacological activity. The compound's hydrobromide form ensures better solubility and bioavailability, making it more effective when administered therapeutically. Its molecular framework allows it to interact with specific receptors in the brain, thereby influencing neuronal communication.

In terms of synthesis, Guvacoline Hydrobromide is typically derived from complex organic reactions involving multiple steps. These reactions require precise control over temperature and pH levels to ensure optimal yield and purity. The synthesis process often involves the use of advanced chromatographic techniques to isolate the final product.

One of the most recent breakthroughs involving Guvacoline Hydrobromide is its application in drug delivery systems. Scientists have developed nanotechnology-based delivery mechanisms to enhance the compound's efficacy and reduce potential side effects. These innovations have opened new avenues for personalized medicine, where treatments can be tailored to individual patient needs.

The pharmacokinetics of CAS 17210-51-4 have also been extensively studied. Research indicates that the compound exhibits moderate absorption rates when administered orally, with peak plasma concentrations achieved within 2-3 hours. Its half-life is relatively short, necessitating frequent dosing schedules for sustained therapeutic effects.

Safety profile assessments have revealed that Guvacoline Hydrobromide is generally well-tolerated at therapeutic doses. However, potential side effects include dizziness, nausea, and mild gastrointestinal disturbances. Long-term studies are currently underway to evaluate the compound's safety profile over extended periods of use.

In conclusion, Guvacoline Hydrobromide (CAS 17210-51-4) represents a significant advancement in pharmacological research. Its unique chemical properties and therapeutic potential make it a valuable tool in addressing various neurological conditions. As research continues to unfold, this compound holds promise for revolutionizing treatment approaches in neuroscience.

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