Cas no 171887-03-9 (N-(2-Amino-4,6-dichloro-5-pyrimidinyl)formamide)

N-(2-Amino-4,6-dichloro-5-pyrimidinyl)formamide is a specialized pyrimidine derivative with significant utility in organic synthesis and pharmaceutical research. Its dichloro-substituted pyrimidine core enhances reactivity, making it a valuable intermediate for constructing heterocyclic compounds. The presence of both amino and formamide functional groups allows for versatile chemical modifications, facilitating its use in the development of biologically active molecules. This compound exhibits high purity and stability under standard conditions, ensuring reliable performance in synthetic applications. Its structural features make it particularly useful in medicinal chemistry for designing targeted therapeutics, including kinase inhibitors and antimicrobial agents. Proper handling and storage are recommended to maintain its integrity.
N-(2-Amino-4,6-dichloro-5-pyrimidinyl)formamide structure
171887-03-9 structure
Product Name:N-(2-Amino-4,6-dichloro-5-pyrimidinyl)formamide
CAS No:171887-03-9
MF:C5H4Cl2N4O
MW:207.017457962036
MDL:MFCD04112936
CID:65907
PubChem ID:87560674
Update Time:2025-10-29

N-(2-Amino-4,6-dichloro-5-pyrimidinyl)formamide Chemical and Physical Properties

Names and Identifiers

    • N-(2-Amino-4,6-dichloropyrimidine-5-yl)formamide
    • 2-Amino-4,6-dichloro-5-pyrimidinyl formamide
    • 2,5-Diamino-4,6-DichloroformamidoHcl
    • N-(2-AMINO-4,6-DICHLOROPYRIMIDIN-5-YL) FORMAMIDE[FOR ABACAVIR]
    • 2-Amino-4,6-dichloro-5-formamidopyrimidine
    • N-(2-Amino-4,6-dichloro-5-pyrimidinyl)formamide
    • N-(2-Amino-4,6-dichloropyrimidin-5-yl)formamide
    • FADCP
    • 2-Amino-4,6-dichloro-5-
    • 2-Amino-4,6-dichloro-5-formanido pyrimidine
    • N-(2-Amino-4.6-dichloro-5-pyrimdinyl) formamide
    • N-(2-Amino-4,6-Dichloro-5-Pyri
    • 171887-03-9
    • N- pound 2-Amino-4,6- dichloropyrimidin -5-yl pound(c)formamide
    • Formamide, N-(2-amino-4,6-dichloro-5-pyrimidinyl)-
    • N-(2-amino-4,6-dichloro-pyrimidin-5-yl)formamide
    • KSC496Q7B
    • N-(2-Amino-4,6- dichloropyrimidin -5-yl) formamide
    • Jsp003510
    • XYWHZ
    • DTXSID30436651
    • N-(2-Amino-4,6-dichloro-5-pyrmidinyl)formamide
    • AKOS015854991
    • N-(2-amino-4,6-dichloropyrimidin-5-yl)-formamide
    • SY030956
    • 2-Amino-4,6-dichloro-5-formamido pyrimidine
    • N-(2-Amino-4,6dichloro-5-pyrimidinyl)formamide
    • CS-W015293
    • AS-15705
    • N-(2-amino-4,6-dichloro-pyrimidin-5-yl)-formamide
    • SCHEMBL536664
    • C5H4Cl2N4O
    • FT-0643648
    • 4H-1-Benzopyran-4-one-2,3-dihydro-7-hydroxy-(9CI)
    • N-[2-azanyl-4,6-bis(chloranyl)pyrimidin-5-yl]methanamide
    • MFCD04112936
    • AM84604
    • N-(2-Amino-4,6-dichloro-5-primidinyl)formamide
    • BCP22646
    • N-(2-amino-4,6-dichloro-5-pyrimidinyl) formamide
    • SB60473
    • A811363
    • EC 425-650-6
    • AC-1437
    • XYWHZUCZNRMJGO-UHFFFAOYSA-N
    • N-(2-Amino-4,6-dichloro-5-pyrimdinyl)formamide
    • A2146
    • STL242902
    • BBL030214
    • DB-043875
    • MDL: MFCD04112936
    • Inchi: 1S/C5H4Cl2N4O/c6-3-2(9-1-12)4(7)11-5(8)10-3/h1H,(H,9,12)(H2,8,10,11)
    • InChI Key: XYWHZUCZNRMJGO-UHFFFAOYSA-N
    • SMILES: ClC1C(=C(N=C(N)N=1)Cl)NC=O

Computed Properties

  • Exact Mass: 205.97600
  • Monoisotopic Mass: 205.9762162g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 12
  • Rotatable Bond Count: 1
  • Complexity: 158
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 80.9
  • Surface Charge: 0
  • Tautomer Count: 4
  • XLogP3: 1

Experimental Properties

  • Color/Form: No data available
  • Density: 1.742
  • Melting Point: 259-264°C
  • Boiling Point: 555℃ at 760 mmHg
  • Flash Point: 289.3±32.9 °C
  • Refractive Index: 1.706
  • PSA: 80.90000
  • LogP: 2.22400

N-(2-Amino-4,6-dichloro-5-pyrimidinyl)formamide Security Information

N-(2-Amino-4,6-dichloro-5-pyrimidinyl)formamide Customs Data

  • HS CODE:29036990
  • Customs Data:

    China Customs Code:

    2933599090

    Overview:

    2933599090. Other compounds with pyrimidine ring in structure(Including other compounds with piperazine ring on the structure. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

    Summary:

    2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

N-(2-Amino-4,6-dichloro-5-pyrimidinyl)formamide Pricemore >>

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N-(2-Amino-4,6-dichloro-5-pyrimidinyl)formamide Production Method

N-(2-Amino-4,6-dichloro-5-pyrimidinyl)formamide Suppliers

Tiancheng Chemical (Jiangsu) Co., Ltd
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Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 11:57
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Jiangsu Xinsu New Materials Co., Ltd
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Suzhou Senfeida Chemical Co., Ltd
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(CAS:171887-03-9)N-(2-Amino-4,6-dichloro-5-pyrimidinyl)formamide
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Purity:99.9%
Pricing Information Last Updated:Friday, 19 July 2024 14:36
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Additional information on N-(2-Amino-4,6-dichloro-5-pyrimidinyl)formamide

N-(2-Amino-4,6-Dichloro-5-Pyrimidinyl)Formamide: A Comprehensive Overview

N-(2-Amino-4,6-Dichloro-5-Pyrimidinyl)Formamide, also known by its CAS number 171887-03-9, is a highly specialized organic compound with significant applications in various scientific and industrial domains. This compound belongs to the class of formamides, which are derivatives of formic acid. Its structure features a pyrimidine ring substituted with amino and dichloro groups, making it a unique molecule with potential for diverse chemical reactivity and biological activity.

The synthesis of N-(2-Amino-4,6-Dichloro-5-Pyrimidinyl)Formamide typically involves multi-step organic synthesis. The starting material is often a pyrimidine derivative, which undergoes substitution or addition reactions to introduce the amino and dichloro functionalities. The final step involves the formation of the formamide group through a reaction with formic acid or its derivatives. This compound is notable for its stability under various conditions, which makes it suitable for use in demanding chemical environments.

Recent studies have highlighted the potential of N-(2-Amino-4,6-Dichloro-5-Pyrimidinyl)Formamide in the field of pharmacology. Researchers have explored its role as a precursor in the synthesis of bioactive compounds, particularly in the development of antiviral and anticancer agents. The presence of the pyrimidine ring is particularly advantageous, as such structures are often found in nucleic acids and are thus relevant to many biological processes.

In addition to its pharmacological applications, this compound has shown promise in materials science. Its ability to form stable complexes with metal ions has led to investigations into its use as a ligand in coordination chemistry. This property could potentially be exploited in the development of new materials for catalysis or sensing applications.

The environmental impact of N-(2-Amino-4,6-Dichloro-5-Pyrimidinyl)Formamide is another area of active research. Studies have been conducted to assess its biodegradability and toxicity to aquatic organisms. Preliminary results suggest that it has low toxicity under standard test conditions, but further research is needed to fully understand its environmental fate and potential risks.

In terms of industrial applications, this compound is used as an intermediate in the synthesis of more complex molecules. Its versatility allows it to be employed in a wide range of chemical processes, from agrochemicals to specialty chemicals. The demand for such compounds continues to grow as industries seek more efficient and sustainable production methods.

The latest advancements in computational chemistry have provided new insights into the properties of N-(2-Amino-4,6-Dichloro-5-Pyrimidinyl)Formamide. Quantum mechanical calculations have been used to study its electronic structure and reactivity, offering valuable information for optimizing synthetic routes and predicting its behavior in different chemical systems.

In conclusion, N-(2-Amino-4,6-Dichloro-5-Pyrimidinyl)Formamide (CAS No: 171887-03-9) is a versatile compound with a wide range of applications across various scientific disciplines. Its unique structure and properties make it an invaluable tool for researchers and industries alike. As ongoing research continues to uncover new uses and improve our understanding of this compound, its role in advancing science and technology is likely to expand further.

Recommended suppliers
Tiancheng Chemical (Jiangsu) Co., Ltd
(CAS:171887-03-9)N-(2-Amino-4,6-dichloro-5-pyrimidinyl)formamide
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Purity:99%/99%
Quantity:25KG,200KG,1000KG/25KG,200KG,1000KG
Price ($):Inquiry/Inquiry
Email
Jiangsu Xinsu New Materials Co., Ltd
(CAS:171887-03-9)
SFD2201
Purity:99%
Quantity:25KG,200KG,1000KG
Price ($):Inquiry
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