• 1. Label-free selective detection of coralyne due to aptamer–coralyne interaction using DNA modified SiO2@Au core–shell nanoparticles as an effective SERS substrate
  Yilin Lu,Qing Huang Anal. Methods 2013 5 3927
• 2. A label-free and sensitive fluorescence strategy for screening ligands binding to poly(dA) based on exonuclease I-assisted background noise reduction
  Hai-Bo Wang,Yong-Hong Li,Ke-Jing Huang,Xin-Sheng Liu,Yan-E. Yang,Yan-Ming Liu Anal. Methods 2013 5 4852

• Solvents and Organic Chemicals Organic Compounds Alkaloids and derivatives Protoberberine alkaloids and derivatives Protoberberine alkaloids and derivatives
• Solvents and Organic Chemicals Organic Compounds Alkaloids and derivatives Protoberberine alkaloids and derivatives
• Pharmaceutical and Biochemical Products Pharmaceutical Active Ingredients Standard Substances

Comprehensive Guide to Palmatine Chloride (CAS No. 171869-95-7): Properties, Applications, and Research Insights

Palmatine Chloride (CAS No. 171869-95-7) is a bioactive alkaloid derived from natural sources such as Berberis and Coptis plants. Known for its vibrant yellow color and diverse pharmacological properties, this compound has garnered significant attention in modern research. With the rise of interest in natural products and plant-based therapeutics, Palmatine Chloride is increasingly studied for its potential health benefits, including antioxidant, anti-inflammatory, and metabolic regulatory effects.

The chemical structure of Palmatine Chloride features a quaternary isoquinoline backbone, which contributes to its stability and bioactivity. Researchers are particularly interested in its role in gut microbiota modulation and glucose metabolism, topics trending in nutritional science and functional food industries. Recent studies also explore its synergy with other berberine-type alkaloids, a hot topic in phytochemical synergy research.

In the pharmaceutical sector, Palmatine Chloride is investigated for its potential in cardiovascular health and neuroprotection, aligning with growing consumer demand for natural alternatives to synthetic drugs. Its mechanism of action, particularly in AMPK pathway activation, is a frequent subject in PubMed and Google Scholar queries. Additionally, its application in cosmeceuticals for skin brightening and anti-aging formulations reflects the booming clean beauty movement.

From an industrial perspective, Palmatine Chloride is valued for its high purity standards (≥98% by HPLC) and compatibility with green chemistry extraction methods. Manufacturers emphasize sustainable sourcing to meet the demands of eco-conscious consumers. Analytical techniques like LC-MS and NMR are critical for quality control, ensuring compliance with USP and EP monographs.

Emerging trends highlight its potential in personalized medicine, especially for type 2 diabetes management, a frequently searched health topic. Comparative studies with berberine HCl often appear in patient forums and health blogs, underscoring public interest. Future research may focus on nanocarrier delivery systems to enhance bioavailability, a cutting-edge area in pharmaceutical technology.

In summary, Palmatine Chloride (CAS No. 171869-95-7) bridges traditional medicine and modern science, offering multifaceted applications. Its alignment with holistic wellness trends and rigorous scientific validation positions it as a compound of enduring relevance in biomedical research and nutraceutical development.

• 19716-66-6(Pseudopalmatine)
• 3486-66-6(Coptisine)
• 3621-36-1(Columbamine)
• 2086-83-1(Berberine)
• 3621-38-3(Jatrorrhizine)
• 25459-91-0(Demethyleneberberine)
• 16176-68-4(Palmaturbine)
• 6873-09-2(Epiberberine)
• 38691-95-1(Groenlandicine)
• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)