Cas no 171661-55-5 ((5-Methylthien-2-yl)methylamine Hydrochloride)

(5-Methylthien-2-yl)methylamine Hydrochloride is a heterocyclic amine derivative featuring a thiophene ring substituted with a methyl group at the 5-position and an aminomethyl group at the 2-position, in its hydrochloride salt form. This compound is of interest in pharmaceutical and agrochemical research due to its potential as a versatile intermediate in the synthesis of bioactive molecules. The hydrochloride salt enhances stability and solubility, facilitating handling and storage. Its structural motif is valuable for constructing ligands or modulators targeting specific receptors or enzymes. The product is typically characterized by high purity, ensuring reproducibility in synthetic applications. Proper storage under anhydrous conditions is recommended to maintain integrity.
(5-Methylthien-2-yl)methylamine Hydrochloride structure
171661-55-5 structure
Product Name:(5-Methylthien-2-yl)methylamine Hydrochloride
CAS No:171661-55-5
MF:C6H10ClNS
MW:163.668299198151
MDL:MFCD09817548
CID:134506
PubChem ID:24229725
Update Time:2025-11-01

(5-Methylthien-2-yl)methylamine Hydrochloride Chemical and Physical Properties

Names and Identifiers

    • (5-Methylthiophen-2-yl)methanamine hydrochloride
    • (5-Methylthien-2-yl)methylamine hydrochloride
    • [(5-Methyl-2-thienyl)methyl]amine hydrochloride
    • 2-Thiophenemethanamine,5-methyl-, hydrochloride (1:1)
    • QC-6113
    • 5-Methyl-2-thiophenemethanamine hydrochloride
    • 2-(Aminomethyl)-5-methylthiophene hydrochloride
    • C-(5-Methyl-thiophen-2-yl)-methylamine hydrochloride
    • (5-Methylthien-2-yl)methylamine, HCl
    • (5-methylthiophen-2-yl)methanaminehydrochloride
    • (5-Methylthien-2-yl)methylamine HCl
    • MFCD09817548
    • CS-0036528
    • EN300-7361553
    • AKOS015894588
    • (5-methylthiophen-2-yl)methanamine;hydrochloride
    • CHEBI:194966
    • 1-(5-Methylthiophen-2-yl)methanamine--hydrogen chloride (1/1)
    • PS-8745
    • (5-Methyl-thiophen-2-yl)methylamine hydrochloride
    • (5-Methyl-2-thienyl)methanamine Hydrochloride
    • SY122882
    • WGA66155
    • FT-0762591
    • DTXSID40640429
    • 2-Thiophenemethanamine,5-methyl-,hydrochloride(1:1)
    • SCHEMBL13731096
    • COTMVCYERKXKDX-UHFFFAOYSA-N
    • (5-methylthien-2-yl)methylamine-HCl
    • (5-methylthiophen-2-yl)methanamine hcl
    • 2-Thiophenemethanamine, 5-methyl-, hydrochloride
    • AMY4599
    • 171661-55-5
    • SB34224
    • 2-(Aminomethyl)-5-methylthiophenehydrochloride97%
    • 2-(Aminomethyl)-5-methylthiophene hydrochloride 97%
    • DB-064826
    • (5-Methylthien-2-yl)methylamine Hydrochloride
    • MDL: MFCD09817548
    • Inchi: 1S/C6H9NS.ClH/c1-5-2-3-6(4-7)8-5;/h2-3H,4,7H2,1H3;1H
    • InChI Key: COTMVCYERKXKDX-UHFFFAOYSA-N
    • SMILES: Cl.S1C(C)=CC=C1CN

Computed Properties

  • Exact Mass: 163.02200
  • Monoisotopic Mass: 163.0222482g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 1
  • Heavy Atom Count: 9
  • Rotatable Bond Count: 1
  • Complexity: 74.9
  • Covalently-Bonded Unit Count: 2
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 54.3?2

Experimental Properties

  • Melting Point: 197-198 oC
  • Boiling Point: 239.3°C at 760 mmHg
  • Flash Point: 98.5°C
  • PSA: 54.26000
  • LogP: 3.01750

(5-Methylthien-2-yl)methylamine Hydrochloride Security Information

(5-Methylthien-2-yl)methylamine Hydrochloride Customs Data

  • HS CODE:2934999090
  • Customs Data:

    China Customs Code:

    2934999090

    Overview:

    2934999090. Other heterocyclic compounds. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

(5-Methylthien-2-yl)methylamine Hydrochloride Pricemore >>

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(5-Methylthien-2-yl)methylamine Hydrochloride Related Literature

Additional information on (5-Methylthien-2-yl)methylamine Hydrochloride

Comprehensive Overview of (5-Methylthien-2-yl)methylamine Hydrochloride (CAS No. 171661-55-5)

(5-Methylthien-2-yl)methylamine Hydrochloride is a specialized organic compound with significant applications in pharmaceutical research and chemical synthesis. Its CAS number, 171661-55-5, serves as a unique identifier in global chemical databases, ensuring precise tracking and regulatory compliance. This compound, often abbreviated as 5-MTMA HCl, is widely recognized for its role as a versatile intermediate in the development of bioactive molecules, particularly in the fields of neurology and metabolic studies.

The molecular structure of (5-Methylthien-2-yl)methylamine Hydrochloride features a thiophene ring substituted with a methyl group at the 5-position, coupled with an amine functional group. This configuration enhances its reactivity, making it valuable for cross-coupling reactions and N-functionalization processes. Researchers frequently explore its potential in designing small-molecule inhibitors and ligands for receptor targeting, aligning with current trends in precision medicine and drug discovery.

In recent years, the demand for high-purity intermediates like 171661-55-5 has surged due to advancements in high-throughput screening (HTS) and combinatorial chemistry. Laboratories prioritize compounds with well-documented synthetic pathways and scalability, both of which are associated with this product. Its hydrochloride salt form improves stability and solubility, addressing common challenges in formulation development.

From an industrial perspective, (5-Methylthien-2-yl)methylamine Hydrochloride is synthesized under controlled conditions to meet Good Manufacturing Practice (GMP) standards. Analytical techniques such as HPLC, NMR, and mass spectrometry are employed to verify its purity, often exceeding 98%. These quality assurances cater to the stringent requirements of contract research organizations (CROs) and academic institutions.

Environmental and safety considerations are integral to its handling. While not classified as hazardous under major regulatory frameworks, proper laboratory safety protocols—including ventilation and personal protective equipment (PPE)—are recommended. This aligns with the growing emphasis on green chemistry and sustainable practices in chemical production.

Emerging applications of CAS 171661-55-5 include its exploration in neurotransmitter modulation studies, particularly concerning serotonin and dopamine pathways. Such investigations resonate with public interest in mental health therapeutics and cognitive enhancement, topics frequently searched in scientific and medical forums.

In summary, (5-Methylthien-2-yl)methylamine Hydrochloride exemplifies the intersection of structural versatility and functional utility in modern chemistry. Its relevance to cutting-edge research and adherence to quality benchmarks position it as a critical asset for scientists navigating the complexities of molecular design and therapeutic innovation.

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