Cas no 1712-70-5 (p-Chloro-alpha-methylstyrene)
p-Chloro-alpha-methylstyrene Chemical and Physical Properties
Names and Identifiers
-
- 1-Chloro-4-(prop-1-en-2-yl)benzene
- Chloromethylstyrenetech
- 4-Chloro-alpha-methylstyrene
- 4-Chloro-alpha-methylstyrene (stabilized with TBC)
- 4-Chloro-α-methylstyrene
- p-Chloro-alpha-methylstyrene
- 4-Chloroisopropenylbenzene
- 4-Isopropenylchlorobenzene
- 4-Chloroisopropenylbenzene (stabilized with TBC)
- 4-Isopropenylchlorobenzene (stabilized with TBC)
- 4-Isopropenyl-chlorobenzene
- 4-CHLORO-A-METHYLSTYRENE
- 4-chloro-à-methylstyrene
- 2-(4-CHLOROPHENYL)PROPENE
- p-Chloroisopropenylbenzene
- p-Isopropenyl-chlorobenzene
- 1-Chloro-4-(prop-1-en-2-yl)
- Benzene, 1-chloro-4-(1-methylethenyl)-
- 4-Chloro-
- A-methylstyrene
- 4-Chloro-.alpha.-methylstyrene
- WQDGTJOEMPEHHL-UHFFFAOYSA-N
- alpha-Methyl-4-chlorostyrene
- 1-Chloro-4-isopropenylbenzen
- P-Chloro-alfa-methylstyrene
- p-Chloro-.alpha.-methylstyrene
- 1-chloro-4-prop-1-en-2-ylbenzene
- 1-Chloro-4-isopropenylbenzene #
- MFCD00000630
- SCHEMBL12113014
- 4-ClC6H4C(CH3)=CH2
- FT-0618161
- BS-44046
- CS-W018084
- 1712-70-5
- 4-Chloro- alpha -methylstyrene
- BAA71270
- AI3-19142
- 4-Chloro-+/--methylstyrene
- AKOS003632743
- SCHEMBL190531
- EINECS 216-984-1
- NS00025620
- 1-chloro-4-isopropenyl-benzene
- WLZ3307
- 4-chloro-alpha-methyl styrene
- 4-Chloro-alpha-methylstyrene, 98%, contains 100 ppm tert-butylcatechol as stabilizer
- DTXSID40169024
- D89216
- SY048599
- W-107875
- EN300-7124629
- DB-043860
- DTXCID5091515
- 216-984-1
-
- MDL: MFCD00000630
- Inchi: 1S/C9H9Cl/c1-7(2)8-3-5-9(10)6-4-8/h3-6H,1H2,2H3
- InChI Key: WQDGTJOEMPEHHL-UHFFFAOYSA-N
- SMILES: ClC1C=CC(=CC=1)C(=C)C
- BRN: 1855073
Computed Properties
- Exact Mass: 152.03900
- Monoisotopic Mass: 152.039
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 0
- Heavy Atom Count: 10
- Rotatable Bond Count: 1
- Complexity: 121
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Surface Charge: 0
- Tautomer Count: nothing
- XLogP3: 4.4
- Topological Polar Surface Area: 0
Experimental Properties
- Color/Form: Colorless transparent or light yellow liquid
- Density: 1.075
- Melting Point: 3.5
- Boiling Point: 205-207 oC
- Flash Point: 73 oC
- Refractive Index: 1.553-1.557
- Water Partition Coefficient: Soluble in water.
- PSA: 0.00000
- LogP: 3.37310
- Sensitiveness: Thermal sensitivity
- Solubility: Insoluble in water.
p-Chloro-alpha-methylstyrene Security Information
-
Symbol:
- Prompt:warning
- Hazard Statement: H227-H411
- Warning Statement: P210-P273-P280-P370+P378-P391-P403+P235-P501
- Hazardous Material transportation number:3082
- WGK Germany:3
- Safety Instruction: S23-S24/25
- HazardClass:9
- PackingGroup:III
- Storage Condition:0-10°C
- Safety Term:S24/25
p-Chloro-alpha-methylstyrene Customs Data
- HS CODE:29036990
- Customs Data:
China Customs Code:
2903999090Overview:
2903999090 Other aromatic halogenated derivatives. VAT:17.0% Tax refund rate:9.0% Regulatory conditions:nothing MFN tariff:5.5% general tariff:30.0%
Declaration elements:
Product Name, component content, use to
Summary:
2903999090 halogenated derivatives of aromatic hydrocarbons VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%
p-Chloro-alpha-methylstyrene Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Alichem | A019089480-500g |
1-Chloro-4-(prop-1-en-2-yl)benzene |
1712-70-5 | 95% stabilized with 100ppm TBC | 500g |
718.08 USD | 2021-06-17 | |
| Chemenu | CM276989-500g |
1-Chloro-4-(prop-1-en-2-yl)benzene |
1712-70-5 | 95% | 500g |
$658 | 2021-06-16 | |
| SHANG HAI YI EN HUA XUE JI SHU Co., Ltd. | R014016-5g |
p-Chloro-alpha-methylstyrene |
1712-70-5 | 90% | 5g |
¥128 | 2024-05-25 | |
| TRC | B419453-50mg |
1-Chloro-4-prop-1-en-2-ylbenzene |
1712-70-5 | 50mg |
$ 50.00 | 2022-06-07 | ||
| TRC | B419453-100mg |
1-Chloro-4-prop-1-en-2-ylbenzene |
1712-70-5 | 100mg |
$ 65.00 | 2022-06-07 | ||
| TRC | B419453-500mg |
1-Chloro-4-prop-1-en-2-ylbenzene |
1712-70-5 | 500mg |
$ 80.00 | 2022-06-07 | ||
| SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd. | C804791-5g |
4-Chloro-α-methylstyrene |
1712-70-5 | >90%(GC),100 ppm | 5g |
198.00 | 2021-05-17 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | OV381-5g |
p-Chloro-alpha-methylstyrene |
1712-70-5 | 97% | 5g |
¥120.0 | 2022-06-10 | |
| FUJIFILM | 324-74821-5g |
p-Chloro-alpha-methylstyrene |
1712-70-5 | 5g |
JPY 4,750 | 2021-12-01 | ||
| FUJIFILM | 322-74822-25g |
p-Chloro-alpha-methylstyrene |
1712-70-5 | 25g |
JPY 16,800 | 2021-12-01 |
p-Chloro-alpha-methylstyrene Suppliers
p-Chloro-alpha-methylstyrene Related Literature
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Cheng-Yong Wang,Jiang-Xi Yu,Bang Liu,Fu-Xing Zhang,Zhi-Qiang Wang,Qin-Yu Hu,Zhi-Feng Xu,Jin-Heng Li Org. Chem. Front. 2022 9 2939
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Weiya Pu,Dani Sun,Wanyue Fan,Wenwen Pan,Qinghui Chai,Xiaoxing Wang,Yunhe Lv Chem. Commun. 2019 55 4821
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Christopher L. Rock,Ryan J. Trovitch Dalton Trans. 2019 48 461
-
Alexander O. Terent'ev,Olga M. Mulina,Dmitry A. Pirgach,Dmitry V. Demchuk,Mikhail A. Syroeshkin,Gennady I. Nikishin RSC Adv. 2016 6 93476
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Caterina Damiano,Paolo Sonzini,Emma Gallo Chem. Soc. Rev. 2020 49 4867
Additional information on p-Chloro-alpha-methylstyrene
Professional Introduction to Compound with CAS No. 1712-70-5 and Product Name: p-Chloro-alpha-methylstyrene
p-Chloro-alpha-methylstyrene (CAS No. 1712-70-5) is a versatile organic compound that has garnered significant attention in the field of chemical and pharmaceutical research due to its unique structural properties and potential applications. This compound, characterized by a chlorinated aromatic ring and an alpha-methyl substituent on the styrene backbone, exhibits a range of chemical reactivities that make it a valuable intermediate in synthetic chemistry. The presence of the chloro group enhances its electrophilic nature, facilitating various transformations such as nucleophilic aromatic substitution, while the methyl group introduces steric and electronic effects that influence its reactivity and stability.
The< strong>p-Chloro-alpha-methylstyrene molecule is a derivative of styrene, which is widely recognized for its role in polymer production and as a precursor in the synthesis of fine chemicals. The introduction of a chlorine atom at the para position relative to the methyl group creates a compound with distinct electronic and steric characteristics. This modification not only alters the compound's solubility and melting point but also opens up new avenues for functionalization and derivatization. In recent years, researchers have been exploring the potential of< strong>p-Chloro-alpha-methylstyrene as a building block for more complex molecules, particularly in the development of novel pharmaceuticals and agrochemicals.
One of the most compelling aspects of< strong>p-Chloro-alpha-methylstyrene is its utility in cross-coupling reactions, which are fundamental to modern synthetic organic chemistry. The chloro group serves as an excellent leaving group in palladium-catalyzed reactions, enabling the formation of carbon-carbon bonds through processes such as Suzuki-Miyaura coupling, Heck reaction, and Buchwald-Hartwig amination. These reactions are crucial for constructing biaryl systems, which are prevalent in many biologically active compounds. For instance, recent studies have demonstrated the use of< strong>p-Chloro-alpha-methylstyrene in the synthesis of substituted biphenyls, which have shown promise as kinase inhibitors and other therapeutic agents.
The< strong>p-Chloro-alpha-methylstyrene molecule also finds applications in polymer chemistry, where it can be polymerized to form novel materials with tailored properties. The chloro group can influence the polymerization process by acting as an initiator or by participating in side reactions that lead to copolymerization with other monomers. This flexibility allows chemists to design polymers with specific thermal stability, mechanical strength, and chemical resistance. Recent advancements in controlled radical polymerization techniques have enabled the production of block copolymers and brush-like architectures using< strong>p-Chloro-alpha-methylstyrene as one of the monomers. These materials are being explored for their potential use in drug delivery systems, where precise control over molecular weight and architecture is essential.
In addition to its role in organic synthesis, p-Chloro-alpha-methylstyrene has been investigated for its potential biological activities. The combination of a chlorinated aromatic ring and an alkene moiety can confer unique interactions with biological targets. Preliminary studies have suggested that derivatives of< strong>p-Chloro-alpha-methylstyrene may exhibit antimicrobial properties due to their ability to disrupt bacterial cell membranes or interfere with essential metabolic pathways. Further research is needed to fully elucidate these effects and explore their therapeutic implications. The growing interest in natural product-inspired drug discovery has also prompted chemists to use< strong>p-Chloro-alpha-methylstyrene as a scaffold for generating structurally diverse compounds that mimic known bioactive molecules.
The industrial production of< strong>p-Chloro-alpha-methylstyrene is another area of active interest. Current synthetic routes often involve chlorination followed by methylation or vice versa, depending on the desired regioselectivity. Advances in catalytic processes have improved the efficiency and selectivity of these transformations, reducing waste generation and energy consumption. Green chemistry principles are being increasingly applied to develop more sustainable methods for producing< strong>p-Chloro-alpha-methylstyrene, including solvent-free reactions and biocatalytic approaches. These innovations not only enhance economic feasibility but also align with global efforts to minimize environmental impact.
The future prospects for< strong>p-Chloro-alpha-methylstyrene are bright, with ongoing research uncovering new applications and refining synthetic methodologies. As our understanding of molecular interactions deepens, so too does our ability to harness this compound's potential for creating innovative materials and drugs. Collaborative efforts between academia and industry are crucial for translating laboratory discoveries into practical solutions that address societal needs. By leveraging the unique properties of< strong>p-Chloro-alpha-methylstyrene, scientists are paving the way for advancements that could reshape multiple sectors within science and technology.
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