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Introduction to (2S,3R)-3-Acetoxy-2-aminobutanoic Acid (CAS No. 17012-42-9)

(2S,3R)-3-Acetoxy-2-aminobutanoic acid, identified by its CAS number 17012-42-9, is a chiral amino acid derivative that has garnered significant attention in the field of pharmaceutical research and biotechnology. This compound, with its unique stereochemical configuration, exhibits a range of biological activities that make it a valuable candidate for drug development and therapeutic applications.

The molecular structure of (2S,3R)-3-Acetoxy-2-aminobutanoic acid consists of a four-carbon backbone with an amine group at the second carbon and an acetoxyl group at the third carbon. The specific stereochemistry at the second and third positions, denoted as (2S,3R), is crucial for its biological function and interaction with target enzymes and receptors. This stereochemical arrangement influences the compound's solubility, metabolic stability, and binding affinity, making it a critical factor in its potential therapeutic applications.

In recent years, there has been growing interest in the development of chiral amino acid derivatives for their ability to mimic natural biomolecules and interact selectively with biological targets. (2S,3R)-3-Acetoxy-2-aminobutanoic acid is no exception and has been studied for its potential role in various pharmacological pathways. Its structural features make it a promising candidate for inhibiting key enzymes involved in metabolic disorders, inflammation, and cancer.

One of the most compelling aspects of (2S,3R)-3-Acetoxy-2-aminobutanoic acid is its ability to serve as a building block for more complex molecules. In drug design, chiral amino acids are often used to enhance the efficacy and selectivity of therapeutic agents. The presence of both an amine and an acetoxyl group provides multiple sites for functionalization, allowing chemists to tailor the compound's properties for specific applications.

The synthesis of (2S,3R)-3-Acetoxy-2-aminobutanoic acid is a challenging but well-studied process. Researchers have developed various synthetic routes to achieve high enantiomeric purity, which is essential for pharmaceutical applications. One common approach involves asymmetric synthesis using chiral auxiliaries or catalysts. These methods ensure that the final product retains the desired stereochemical configuration, which is critical for its biological activity.

The pharmacological profile of (2S,3R)-3-Acetoxy-2-aminobutanoic acid has been extensively evaluated in preclinical studies. These studies have revealed its potential as an inhibitor of various enzymes, including those involved in the metabolism of lipids and carbohydrates. Additionally, the compound has shown promise in reducing inflammation and preventing the progression of certain types of cancer.

In particular, research has highlighted the compound's ability to modulate the activity of acetyl-CoA carboxylase (ACC), an enzyme critical for fatty acid synthesis. By inhibiting ACC, (2S,3R)-3-Acetoxy-2-aminobutanoic acid can help regulate lipid metabolism and potentially reduce the risk of obesity-related diseases such as type 2 diabetes and cardiovascular disorders.

The anti-inflammatory properties of (2S,3R)-3-Acetoxy-2-aminobutanoic acid

In cancer research, (2S,3R-Acetoxy-butanoyl amine hydrochloride salt ) has shown potential as an anti-proliferative agent. It has been found to induce apoptosis in certain cancer cell lines by disrupting key signaling pathways involved in cell growth and survival. This makes it a promising candidate for developing novel anti-cancer therapies.

The future prospects for (CAS No 17012- 42- 9 ) are bright, with ongoing research aimed at optimizing its pharmacological properties and exploring new therapeutic applications. Advances in synthetic chemistry and biotechnology are expected to further enhance the production efficiency and purity of this compound, making it more accessible for clinical trials and commercialization.

In conclusion, ((2S, 3R) - 3 - Acetoxy - 2 - Aminobutanoic Acid ) is a versatile chiral amino acid derivative with significant potential in pharmaceutical research. Its unique structural features and biological activities make it a valuable tool for developing new drugs targeting metabolic disorders, inflammation, and cancer. As research continues, the therapeutic applications of this compound are expected to expand, offering new hope for patients suffering from various diseases.

• 5854-77-3((2S,3R)-tert-Butyl 2-amino-3-(tert-butoxy)butanoate Acetate)
• 88815-81-0(L-Threonine, methyl ester, hexadecanoate (ester))
• 78061-03-7(H-THR-OTBU ACOH)
• 5854-78-4(O-tert-Butylthreoninetert-butyl ester)
• 66748-90-1(tert-butyl (2S,3R)-2-amino-3-hydroxybutanoate)
• 519156-32-2(H-Thr(Ac)-OH Hydrochloride)
• 764724-41-6(L-Threonine, propylester)
• 38024-14-5(DL-Threonine, O-(1,1-dimethylethyl)-, 1,1-dimethylethyl ester, acetate)
• 88467-31-6(L-Threonine, octadecanoate (ester))
• 88467-30-5(Hexadecanoic acid, (1R,2S)-2-amino-2-carboxy-1-methylethyl ester)