Cas no 169954-68-1 (2-N-Boc-2-Methylpropane-1,2-diamine Hydrochloride)

2-N-Boc-2-Methylpropane-1,2-diamine Hydrochloride is a protected diamine derivative widely used in organic synthesis and pharmaceutical research. The Boc (tert-butoxycarbonyl) group provides stability under basic conditions while allowing selective deprotection under acidic conditions, making it valuable for stepwise reactions. The hydrochloride salt enhances solubility and handling properties. This compound serves as a versatile intermediate in the preparation of peptidomimetics, chiral ligands, and bioactive molecules. Its structural features, including the sterically hindered methyl group, contribute to controlled reactivity and selectivity in asymmetric synthesis. The product is characterized by high purity and consistent performance, ensuring reliable results in complex synthetic pathways.
2-N-Boc-2-Methylpropane-1,2-diamine Hydrochloride structure
169954-68-1 structure
Product Name:2-N-Boc-2-Methylpropane-1,2-diamine Hydrochloride
CAS No:169954-68-1
MF:C9H21ClN2O2
MW:224.728241682053
MDL:MFCD11112239
CID:836414
PubChem ID:45072479
Update Time:2025-08-03

2-N-Boc-2-Methylpropane-1,2-diamine Hydrochloride Chemical and Physical Properties

Names and Identifiers

    • 2-N-BOC-2-METHYLPROPANE-1,2-DIAMINE
    • 2-N-Boc-2-Methylpropane-1,2-diamine hydrochloride
    • 2-N-Boc-2-methylpropane-1,2-diamine-HCl
    • tert-butyl N-(1-amino-2-methylpropan-2-yl)carbamate,hydrochloride
    • (2-Amino-tert-butyl)carbamic acid tert-butyl ester monohydrochloride
    • (2-Amino-1,1-dimethyl-ethyl)-carbamic acid tert-butyl ester hydrochloride
    • AS-47872
    • MFCD11112239
    • 2-N-Boc-2-Methylpropane-1,2-diaminehydrochloride
    • 2-N-BOC-2-METHYLPROPANE-1,2-DIAMINE HCl
    • AKOS015844540
    • SB34193
    • DTXSID30662574
    • 169954-68-1
    • DB-064762
    • CS-0316427
    • tert-butyl (1-amino-2-methylpropan-2-yl)carbamate hydrochloride
    • tert-butyl N-(1-amino-2-methylpropan-2-yl)carbamate;hydrochloride
    • TERT-BUTYL N-(1-AMINO-2-METHYLPROPAN-2-YL)CARBAMATE HYDROCHLORIDE
    • tert-Butyl (1-amino-2-methylpropan-2-yl)carbamate--hydrogen chloride (1/1)
    • F16432
    • 2-N-Boc-2-Methylpropane-1,2-diamine Hydrochloride
    • MDL: MFCD11112239
    • Inchi: 1S/C9H20N2O2.ClH/c1-8(2,3)13-7(12)11-9(4,5)6-10;/h6,10H2,1-5H3,(H,11,12);1H
    • InChI Key: JMLZLOMGUNTNJG-UHFFFAOYSA-N
    • SMILES: Cl.O(C(NC(C)(C)CN)=O)C(C)(C)C

Computed Properties

  • Exact Mass: 224.12900
  • Monoisotopic Mass: 224.1291556g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 14
  • Rotatable Bond Count: 5
  • Complexity: 183
  • Covalently-Bonded Unit Count: 2
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 64.4?2

Experimental Properties

  • PSA: 64.35000
  • LogP: 3.14160

2-N-Boc-2-Methylpropane-1,2-diamine Hydrochloride Security Information

2-N-Boc-2-Methylpropane-1,2-diamine Hydrochloride Customs Data

  • HS CODE:2921290000
  • Customs Data:

    China Customs Code:

    2921290000

    Overview:

    2921290000. Other acyclic polyamines and their derivatives and their salts. VAT:17.0%. Tax refund rate:9.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    2921290000 other acyclic polyamines and their derivatives; salts thereof.Supervision conditions:None.VAT:17.0%.Tax rebate rate:9.0%.MFN tariff:6.5%.General tariff:30.0%

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Additional information on 2-N-Boc-2-Methylpropane-1,2-diamine Hydrochloride

Introduction to 2-N-Boc-2-Methylpropane-1,2-diamine Hydrochloride (CAS No. 169954-68-1)

2-N-Boc-2-Methylpropane-1,2-diamine Hydrochloride, also known by its CAS number 169954-68-1, is a compound of significant interest in the fields of organic chemistry and materials science. This compound is a derivative of propane diamine, with a specific substitution pattern that imparts unique chemical properties. The presence of the Boc (tert-butoxycarbonyl) group and the hydrochloride counterion makes it particularly useful in various synthetic applications.

The structure of 2-N-Boc-2-Methylpropane-1,2-diamine Hydrochloride consists of a propane backbone with two amine groups at the 1 and 2 positions. The 2-position amine is protected by a Boc group, while the hydrochloride ion serves as the counterion for the protonated amine at the 1-position. This structure allows for precise control over reactivity during synthetic processes, making it a valuable intermediate in organic synthesis.

Recent studies have highlighted the potential of this compound in drug discovery and materials science. For instance, researchers have explored its role in the synthesis of bioactive molecules, where its unique functional groups facilitate the construction of complex architectures with high precision. Additionally, its application in polymer chemistry has been investigated, with findings suggesting its utility in creating novel materials with tailored properties.

The synthesis of 2-N-Boc-2-Methylpropane-1,2-diamine Hydrochloride typically involves multi-step processes that emphasize stereochemical control and functional group compatibility. One common approach involves the selective protection of amine groups using Boc reagents, followed by purification to ensure high purity levels required for downstream applications.

In terms of physical properties, this compound exhibits a melting point that is consistent with its molecular weight and functional group composition. Its solubility in common organic solvents makes it suitable for use in various reaction conditions, including those requiring polar aprotic solvents or aqueous environments.

The application of 2-N-Boc-2-Methylpropane-1,2-diamine Hydrochloride extends beyond traditional organic synthesis into emerging areas such as catalysis and green chemistry. Recent advancements have demonstrated its effectiveness as a ligand in transition metal-catalyzed reactions, where it enhances catalytic efficiency and selectivity.

In conclusion, 2-N-Boc-2-Methylpropane-1,2-diamine Hydrochloride (CAS No. 169954-68-1) stands as a versatile compound with a wide range of applications across multiple disciplines. Its unique structure and functional groups make it an invaluable tool for researchers aiming to push the boundaries of chemical synthesis and material innovation.

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