Cas no 1697819-63-8 (2-(1,1,1,3,3,3-hexafluoropropan-2-yl)pyrrolidine)

2-(1,1,1,3,3,3-Hexafluoropropan-2-yl)pyrrolidine is a fluorinated pyrrolidine derivative characterized by the presence of a hexafluoroisopropyl group. This structural feature imparts enhanced lipophilicity and metabolic stability, making it a valuable intermediate in pharmaceutical and agrochemical synthesis. The electron-withdrawing nature of the hexafluoroisopropyl moiety can influence the reactivity and binding affinity of derived compounds, particularly in medicinal chemistry applications. Its rigid, sterically demanding structure may also contribute to improved selectivity in catalytic processes. The compound’s stability under a range of reaction conditions further enhances its utility in fine chemical synthesis. Proper handling is advised due to potential sensitivity to moisture or strong bases.
2-(1,1,1,3,3,3-hexafluoropropan-2-yl)pyrrolidine structure
1697819-63-8 structure
Product Name:2-(1,1,1,3,3,3-hexafluoropropan-2-yl)pyrrolidine
CAS No:1697819-63-8
MF:C7H9F6N
MW:221.143482923508
CID:6442342
PubChem ID:103309329
Update Time:2025-05-20

2-(1,1,1,3,3,3-hexafluoropropan-2-yl)pyrrolidine Chemical and Physical Properties

Names and Identifiers

    • 2-(1,1,1,3,3,3-hexafluoropropan-2-yl)pyrrolidine
    • 1697819-63-8
    • EN300-1930475
    • Inchi: 1S/C7H9F6N/c8-6(9,10)5(7(11,12)13)4-2-1-3-14-4/h4-5,14H,1-3H2
    • InChI Key: GSCNOLVEKHJEGX-UHFFFAOYSA-N
    • SMILES: FC(C(C(F)(F)F)C1CCCN1)(F)F

Computed Properties

  • Exact Mass: 221.06391826g/mol
  • Monoisotopic Mass: 221.06391826g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 7
  • Heavy Atom Count: 14
  • Rotatable Bond Count: 1
  • Complexity: 181
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 1
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 2.8
  • Topological Polar Surface Area: 12?2

2-(1,1,1,3,3,3-hexafluoropropan-2-yl)pyrrolidine Pricemore >>

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