• 1. Emulsifier-free, organotellurium-mediated living radical emulsion polymerization (emulsion TERP) of styrene: poly(dimethylaminoethyl methacrylate) macro-TERP agent?
  Yukiya Kitayama Polym. Chem., 2014,5, 2784-2792
• 2. Evidence of field induced slow magnetic relaxation in cis-[Co(hfac)2(H2O)2] exhibiting tri-axial anisotropy with a negative axial component?
  Denis V. Korchagin,Elena A. Yureva,Alexander V. Akimov,Eugenii Ya. Misochko,Gennady V. Shilov,Artem D. Talantsev,Roman B. Morgunov,Alexander A. Shakin,Sergey M. Aldoshin,Boris S. Tsukerblat Dalton Trans., 2017,46, 7540-7548
• 3. Excellent peroxidase mimicking property of CuO/Pt nanocomposites and their application as an ascorbic acid sensor?
  Xinhuan Wang,Shuangfei Cai,Cui Qi Analyst, 2017,142, 2500-2506
• 4. Establishing the accuracy of position-specific carbon isotope analysis of propane by GC-pyrolysis-GC-IRMS
  ChangjieLiu,PengLiu,XiaofengWang,XiaoqiangLi,JuskeHorita
• 5. Dissociative dynamics of O2 on Ag(110)?
  Ivor Lon?ari? Phys. Chem. Chem. Phys., 2015,17, 9436-9445

• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Piperidines Piperidinecarboxylic acids
• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Piperidines Piperidinecarboxylic acids and derivatives Piperidinecarboxylic acids

Comprehensive Guide to Methyl 1-Methylpiperidine-4-Carboxylate (CAS No. 1690-75-1): Properties, Applications, and Industry Insights

Methyl 1-methylpiperidine-4-carboxylate (CAS No. 1690-75-1) is a versatile organic compound with a growing presence in pharmaceutical and chemical research. This ester derivative of piperidine has garnered attention for its unique structural properties, making it a valuable intermediate in synthetic chemistry. As researchers increasingly explore nitrogen-containing heterocycles, compounds like methyl 1-methylpiperidine-4-carboxylate have become pivotal in drug discovery and material science applications.

The molecular structure of CAS 1690-75-1 features a piperidine ring substituted with both a methyl group and a methyl ester moiety at the 1- and 4-positions, respectively. This configuration contributes to its balanced lipophilicity and polarity, properties that are frequently searched by chemists investigating bioavailability-enhancing scaffolds. Recent literature highlights its utility in constructing CNS-active compounds, with particular interest in its potential role as a conformational constraint element in medicinal chemistry.

In the context of current research trends, methyl 1-methylpiperidine-4-carboxylate aligns with several hot topics in organic synthesis. These include the development of sustainable synthetic methodologies and green chemistry approaches for heterocycle formation. Analytical techniques for characterizing this compound—such as HPLC purity analysis and NMR spectral interpretation—are frequently queried in academic search engines, reflecting the compound's expanding laboratory applications.

From an industrial perspective, the scale-up synthesis of 1690-75-1 presents interesting challenges that resonate with process chemistry discussions. Optimization parameters like esterification yield improvement and catalyst selection for piperidine derivatives are actively debated in patent literature. The compound's stability profile under various storage conditions is another area of practical concern for chemical manufacturers and distributors.

The pharmacological potential of methyl 1-methylpiperidine-4-carboxylate derivatives continues to inspire research, particularly in neurological and metabolic disorders. While the parent compound itself isn't biologically active, its structural features make it a valuable building block for drug candidates. This aligns with growing search trends for privileged structures in medicinal chemistry and fragment-based drug design strategies.

Quality control aspects of CAS 1690-75-1 remain crucial for end-users. Specifications including chromatographic purity standards, residual solvent limits, and isomeric impurity thresholds are frequently referenced in technical data sheets. These parameters directly impact the compound's performance in downstream applications, making them critical search keywords for procurement specialists.

Emerging applications in material science have expanded the relevance of methyl 1-methylpiperidine-4-carboxylate beyond traditional chemistry domains. Its incorporation into functional polymers and coordination complexes demonstrates the compound's adaptability. Recent publications exploring its use in metal-organic frameworks (MOFs) have generated substantial academic interest, correlating with rising search volumes for nitrogen-rich linkers in advanced materials.

Safety considerations for handling 1690-75-1 follow standard laboratory protocols for organic compounds. While not classified as hazardous, proper personal protective equipment (PPE) and ventilation requirements remain important operational parameters—topics that consistently appear in workplace safety searches across the chemical industry.

The global market for methyl 1-methylpiperidine-4-carboxylate reflects broader trends in fine chemical supply chains. Factors influencing its availability—including raw material sourcing, regional production capacity, and regulatory compliance—are increasingly searched by procurement professionals. These economic aspects complement the technical discussions surrounding this compound.

Future research directions for CAS 1690-75-1 derivatives may explore their potential in asymmetric synthesis and chiral auxiliary applications. The compound's structural features position it well for investigations into stereoselective transformations, a growing area of interest in synthetic methodology development. These prospects align with search trends focusing on enantioselective catalysis and chiral pool strategies.

• 1206228-66-1(Methyl 4-ethylpiperidine-4-carboxylate)
• 102872-28-6(Quinuclidine-4-carboxylic acid methyl ester; hydrochloride)
• 52632-33-4( )
• 99065-42-6(Methyl 1-ethylpiperidine-4-carboxylate)
• 51069-26-2(Methyl quinuclidine-4-carboxylate)
• 892493-16-2(methyl 4-methylpiperidine-4-carboxylate)
• 49637-22-1(1-Piperidinebutanoic acid, alpha-methyl-, ethyl ester)
• 51023-67-7(Piperidinium, 4-(methoxycarbonyl)-1,1-dimethyl-, iodide)
• 869493-51-6(Methyl 1-(3-aminopropyl)piperidine-4-carboxylate)
• 74045-89-9(1-Butyl-piperidine-4-carboxylic Acid ethyl ester)