Cas no 16874-06-9 (L-Glutamic acid,1,5-bis(1,1-dimethylethyl) ester)

L-Glutamic acid,1,5-bis(1,1-dimethylethyl) ester is a protected derivative of L-glutamic acid, where the carboxyl groups are esterified with tert-butyl groups. This modification enhances stability and solubility in organic solvents, making it valuable for peptide synthesis and other applications requiring controlled reactivity. The tert-butyl ester groups act as protecting groups, preventing unwanted side reactions during chemical transformations while allowing selective deprotection under mild acidic conditions. Its high purity and well-defined structure ensure consistent performance in synthetic workflows. This compound is particularly useful in medicinal chemistry and bioconjugation, where precise functional group manipulation is critical.
L-Glutamic acid,1,5-bis(1,1-dimethylethyl) ester structure
16874-06-9 structure
Product Name:L-Glutamic acid,1,5-bis(1,1-dimethylethyl) ester
CAS No:16874-06-9
MF:C13H25NO4
MW:259.341904401779
CID:154250
PubChem ID:208637
Update Time:2025-05-28

L-Glutamic acid,1,5-bis(1,1-dimethylethyl) ester Chemical and Physical Properties

Names and Identifiers

    • L-Glutamic acid,1,5-bis(1,1-dimethylethyl) ester
    • Bis(tert-butyl) L-glutamate
    • L-glutamic acid di-tert-butyl ester
    • L-GLUTAMIC ACID DI-TERT-BUTYLESTER DIBENZENESULFIMIDE SALT
    • di-tert-butyl glutamate
    • di-tert-butyl L-glutamate
    • Einecs 240-900-2
    • a,g-Di-tert-butyl L-g
    • GlutaMic acid, di-tert-butyl ester (6CI)
    • L-Glutamic acid bis(1,1-dimethylethyl) ester
    • GlutaMic acid, di-tert-butyl ester, L- (7CI,8CI)
    • L-GLUTAMIC ACID DI-TERT-BUTYLESTER DIBEN ZENESULFIMIDE SALT
    • H-Glu(OtBu)-OtBu
    • 16874-06-9
    • (S)-Di-tert-butyl 2-aminopentanedioate
    • SCHEMBL18477
    • NTUGPDFKMVHCCJ-VIFPVBQESA-N
    • AKOS028109294
    • 1,5-DI-TERT-BUTYL (2S)-2-AMINOPENTANEDIOATE
    • L-Glutamic acid di tert-butyl ester
    • l-glutamic acid di-t-butyl ester
    • (S)-Di-tert-butyl2-aminopentanedioate
    • L-Glu(OtBu)-OtBu
    • EN300-6494429
    • MFCD00038271
    • L-Glutamic acid,1,5-bis(1,1-dimethylethyl)ester
    • L-Glutamic acid, 1,5-bis(1,1-dimethylethyl) ester
    • HY-20167
    • L-Glutamic acid, bis(1,1-dimethylethyl) ester
    • CS-B0053
    • ditert-butyl (2S)-2-aminopentanedioate
    • H-Glu(OBut)-OBut
    • NS00051861
    • CS-13529
    • LGlu(OtBu)-OtBu
    • (S)-Di-t-butyl 2-aminopentanedioate
    • DA-53973
    • Inchi： 1S/C13H25NO4/c1-12(2,3)17-10(15)8-7-9(14)11(16)18-13(4,5)6/h9H,7-8,14H2,1-6H3/t9-/m0/s1
    • InChI Key： NTUGPDFKMVHCCJ-VIFPVBQESA-N
    • SMILES： O(C([C@H](CCC(=O)OC(C)(C)C)N)=O)C(C)(C)C

Computed Properties

  • Exact Mass: 259.17845
  • Monoisotopic Mass: 259.17835828g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 5
  • Heavy Atom Count: 18
  • Rotatable Bond Count: 8
  • Complexity: 299
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 1
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 1.4
  • Topological Polar Surface Area: 78.6?2

Experimental Properties

  • Melting Point: 139-141?°C (dec.)
  • PSA: 78.62

L-Glutamic acid,1,5-bis(1,1-dimethylethyl) ester Security Information

L-Glutamic acid,1,5-bis(1,1-dimethylethyl) ester Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
ChemScence
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L-Glutamic acid, 1,5-bis(1,1-dimethylethyl) ester
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A236126-100mg
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A236126-250mg
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1PlusChem
1P001YPB-100mg
L-Glutamic acid, 1,5-bis(1,1-dimethylethyl) ester
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AR001YXN-15g
L-Glutamic acid, 1,5-bis(1,1-dimethylethyl) ester
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L-Glutamic acid, 1,5-bis(1,1-dimethylethyl) ester
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