Cas no 16837-52-8 (Oxymatrine)

Oxymatrine is a naturally occurring quinazoline alkaloid extracted from Sophora flavescens, exhibiting potent anti-inflammatory and immunomodulatory properties. Its key advantages include enhanced bioavailability, improved efficacy in reducing inflammatory responses, and potential applications in the treatment of various diseases, including infectious and autoimmune conditions.

Oxymatrine structure

Product Name:Oxymatrine

CAS No:16837-52-8

MF:C₁₅H₂₄N₂O₂

MW:264.3633

MDL:MFCD00210339

CID:50548

PubChem ID:24864132

Update Time:2025-08-28

Oxymatrine Chemical and Physical Properties

Names and Identifiers

- oxymatrine
- Matridin-15-one, 1-oxide, (1-beta)-
- Matrine 1beta-oxide
- Matrine N-oxide
- Matrine oxide
- 1H,5H,10H-Dipyrido(2,1-f:3',2',1'-ij)(1,6)naphthyridin-10-one, dodecahydro-, 4-oxide, (4R,7aS,13aR,13bR,13cS)-
- Matrine, 1-oxide
- Ammothamnine
- (7aS,13aR,13bR,13cS)dodecahydro-1H,5H,10H-dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one 4-oxide
- (2alpha,5beta,7beta,10beta,13alpha)-4,10-bis(acetyloxy)-13-{[(2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoyl]oxy}-1,7-dihydroxy-9-oxo-5,20-epoxytax-11-en-2-yl benzoate
- OXYMATRINE(P) PrintBack
- (4R,7aS,13aR,13bR,13cS)-dodecahydro-1H,5H,10H-dipyrido[2,1-f:3’,2’,1’-ij][1,6]naphthyridin-10-one 4-oxide
- (7aS,13aR,13bR,13cS)-dodecahydro-1H,5H,10H-dipyrido[2,1-f:3’,2’,1’-ij][1,6]naphthyridin-10-one 4-oxide
- Matrine N-oxide Ammothamnine
- Kurainone
- OXYMATRINE(P)
- Oxymatrine,(S)
- Pachycarpidine
- Oxymatrine std.
- [ "Matrine N-oxide", " Ammothamnine" ]
- matrine,1-oxide
- (1R,2R,9S,13S,17S)-13-Oxido-7-aza-13-azoniatetracyclo[7.7.1.02,7.013,17]heptadecan-6-one
- Sophoridine N-oxide
- Oxysophoridine
- Sophoridine, N-oxide
- NSC142988
- UNII-85U4C366QS
- Q63396010
- 85U4C366QS
- (4R,7AS,13AR,13BR,13CS)-DODECAHYDRO-1H,5H,10H-DIPYRIDO(2,1-F:3',2',1'-IJ)(1,6)NAPHTHYRIDIN-10-ONE 4-OXIDE
- CS-6157
- (7AS,13AR,13BR,13CS)-DODECAHYDRO-1H,5H,10H-DIPYRIDO(2,1-F:3',2',1'-IJ)(1,6)NAPHTHYRIDIN-10-ONE 4-OXIDE
- OXYMATRINE [WHO-DD]
- HY-N0158
- HSDB 8102
- 1ST40311
- 16837-52-8
- MFCD00210339
- SCHEMBL13394285
- NCGC00346596-01
- NCGC00346596-02
- Oxymatrine (Matrine N-oxide)
- CHEMBL458337
- (+)-oxymatrine
- AS-15173
- A870349
- 1H,5H,10H-Dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one,dodecahydro-, 4-oxide, (7aR,13aR,13bR,13cS)-
- (1R,2R,9S,17S)-13-oxido-7-aza-13-azoniatetracyclo[7.7.1.02,7.013,17]heptadecan-6-one
- Q15425294
- s2338
- 1212383-03-3
- XVPBINOPNYFXID-LHDUFFHYSA-N
- (1R,2R,9S,13R,17S)-13-Oxido-7-aza-13-azoniatetracyclo[7.7.1.02,7.013,17]heptadecan-6-one
- HMS2854E03
- AC-6063
- AKOS004120031
- CHEBI:2672
- MLS001215101
- (1R,2R,9S,17S)-6-oxo-7,13-diazatetracyclo[7.7.1.0?,?.0??,??]heptadecan-13-ium-13-olate
- SMR000543093
- BDBM50597716
- Q-100202
- AMY25589
- rel-(41S,7aS,13aR,13bR)-10-Oxohexadecahydrodipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridine4-oxide
- AKOS022168212
- NS00018296
- rel-(41S,7aS,13aR,13bR)-10-Oxohexadecahydrodipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridine 4-oxide
- MLS006011817
- DTXSID40937482
- 54809-74-4
- CCG-267091
- BBL030371
- STK801916
- Oxymatrine
- MDL： MFCD00210339
- Inchi： 1S/C15H24N2O2/c18-14-7-1-6-13-12-5-3-9-17(19)8-2-4-11(15(12)17)10-16(13)14/h11-13,15H,1-10H2
- InChI Key： XVPBINOPNYFXID-UHFFFAOYSA-N
- SMILES： [O-][N+]12C([H])([H])C([H])([H])C([H])([H])C3([H])C([H])([H])N4C(C([H])([H])C([H])([H])C([H])([H])C4([H])C([H])(C([H])([H])C([H])([H])C1([H])[H])C23[H])=O

Computed Properties

Exact Mass: 264.18400
Monoisotopic Mass: 264.184
Isotope Atom Count: 0
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 2
Heavy Atom Count: 19
Rotatable Bond Count: 0
Complexity: 400
Covalently-Bonded Unit Count: 1
Defined Atom Stereocenter Count: 4
Undefined Atom Stereocenter Count : 1
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Topological Polar Surface Area: 38.4A^2
Isotope Atom Count: 0
Surface Charge: 0
Tautomer Count: 2
Molecular Weight: 264.36
XLogP3: 1
Topological Polar Surface Area: 38.4

Experimental Properties

Color/Form: White or off white crystalline powder
Density: 1.399g/cm3
Melting Point: 208℃
Boiling Point: 957.1℃ at 760 mmHg
Flash Point: 532.644°C
Refractive Index: 1.637
Solubility: methanol: soluble10mg/mL, clear, colorless
PSA: 49.74000
LogP: 1.78100
Odor: Slight amber aroma
Solubility: Not determined
Vapor Pressure: 8.75X10-11 mm Hg at 25 °C (est)

Oxymatrine Security Information

Signal Word：Warning
Hazard Statement： H302
Warning Statement： P280-P305+P351+P338
Hazard Category Code： 22-20/22
Safety Instruction： 24/25
RTECS：OQ1770000
Hazardous Material Identification：
Storage Condition：Powder -20°C 3 years ? 4°C 2 years In solvent -80°C 6 months ? -20°C 1 month

Oxymatrine Pricemore >>

Related Categories	No.	Product Name	Cas No.	Purity	Specification	Price	update time
SHANG HAI XIAN DING Biotechnology Co., Ltd.	A-IK276-5g	Oxymatrine	16837-52-8	97%	5g	￥276.0	2022-06-10
SHANG HAI XIAN DING Biotechnology Co., Ltd.	A-IK276-1g	Oxymatrine	16837-52-8	97%	1g	￥97.0	2022-06-10
TRC	O876300-100mg	Oxymatrine	16837-52-8		100mg	$ 98.00	2023-09-06
TRC	O876300-250 mg	Oxymatrine	16837-52-8		250MG	125.00	2021-07-22
TRC	O876300-500 mg	Oxymatrine	16837-52-8		500MG	160.00	2021-07-22
TRC	O876300-1 g	Oxymatrine	16837-52-8		1g	220.00	2021-07-22
Chengdu Biopurify Phytochemicals Ltd	BP1049-1000mg	Oxymatrine	16837-52-8	98%	1000mg	$60	2023-09-20
Chengdu Biopurify Phytochemicals Ltd	BP1049-20mg	Oxymatrine	16837-52-8	98%	20mg	$20	2023-09-20
Chengdu Biopurify Phytochemicals Ltd	BP1049-100mg	Oxymatrine	16837-52-8	98%	100mg	$40	2023-09-20
SHANG HAI TAO SHU Biotechnology Co., Ltd.	T2754-25 mg	Oxymatrine	16837-52-8	99.84%	25mg	￥277.00	2022-04-26

Oxymatrine Production Method

Oxymatrine Suppliers

Tiancheng Chemical (Jiangsu) Co., Ltd

Gold Member

Audited Supplier

(CAS:16837-52-8)Oxymatrine

Order Number:LE948;LE10240

Stock Status:in Stock

Quantity:25KG,200KG,1000KG

Purity:99%

Pricing Information Last Updated:Friday, 20 June 2025 11:39

Price ($):discuss personally

Email:[email protected]

Suzhou Senfeida Chemical Co., Ltd

Gold Member

Audited Supplier

(CAS:16837-52-8)Ammothamnine

Order Number:sfd6845

Stock Status:in Stock

Quantity:200kg

Purity:99.9%

Pricing Information Last Updated:Friday, 19 July 2024 14:34

Price ($):discuss personally

Email:[email protected]

Product Official Link

Oxymatrine Spectrogram

LC-MS

1H NMR

300 MHz

DMSO

13C NMR

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Saeideh Mirfakhraei,Malak Hekmati,Fereshteh Hosseini Eshbala,Hojat Veisi New J. Chem., 2018,42, 1757-1761
3. Esterase-responsive polymeric prodrug-based tumor targeting nanoparticles for improved anti-tumor performance against colon cancer?

Gang Pan,Yi-jie Bao,Jie Xu,Tao Liu,Cheng Liu,Yan-yan Qiu,Xiao-jing Shi,Hui Yu,Ting-ting Jia,Xia Yuan,Ze-ting Yuan,Yi-jun Cao RSC Adv., 2016,6, 42109-42119
4. Fe3O4 nanoclusters highly dispersed on a porous graphene support as an additive for improving the hydrogen storage properties of LiBH4?

Guang Xu,Wei Zhang,Ying Zhang,Xiaoxia Zhao,Ping Wen,Di Ma RSC Adv., 2018,8, 19353-19361
5. Evidence for the intrinsic nature of band-gap states electrochemically observed on atomically flat TiO2(110) surfaces?

Shintaro Takata,Yoshihiro Miura Phys. Chem. Chem. Phys., 2014,16, 24784-24789

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