Cas no 1660110-86-0 ((4aS,7aS)-Octahydrocyclopenta[b][1,4]oxazine hydrochloride)

(4aS,7aS)-Octahydrocyclopenta[b][1,4]oxazine hydrochloride is a chiral bicyclic compound featuring a fused cyclopentane-oxazine ring system. Its rigid, saturated structure enhances stereochemical stability, making it valuable as a building block in pharmaceutical synthesis, particularly for bioactive molecules requiring precise spatial orientation. The hydrochloride salt improves solubility and handling in aqueous or polar organic solvents. This scaffold is often employed in the development of CNS-targeting agents, owing to its ability to mimic privileged pharmacophores. Its defined stereochemistry (4aS,7aS) ensures reproducibility in asymmetric synthesis. The compound’s stability under typical reaction conditions further supports its utility in multistep synthetic routes.
(4aS,7aS)-Octahydrocyclopenta[b][1,4]oxazine hydrochloride structure
1660110-86-0 structure
Product Name:(4aS,7aS)-Octahydrocyclopenta[b][1,4]oxazine hydrochloride
CAS No:1660110-86-0
MF:C7H14ClNO
MW:163.645161151886
CID:5141238
PubChem ID:90235929
Update Time:2026-03-03

(4aS,7aS)-Octahydrocyclopenta[b][1,4]oxazine hydrochloride Chemical and Physical Properties

Names and Identifiers

    • Cyclopent[b]-1,4-oxazine, octahydro-, hydrochloride (1:1), (4aS,7aS)-
    • (4aS,7aS)-Octahydrocyclopenta[b][1,4]oxazine hydrochloride
    • 1660110-86-0
    • F75243
    • SCHEMBL15817082
    • Inchi: 1S/C7H13NO.ClH/c1-2-6-7(3-1)9-5-4-8-6;/h6-8H,1-5H2;1H/t6-,7-;/m0./s1
    • InChI Key: JWEHBYVWAVHAEP-LEUCUCNGSA-N
    • SMILES: [C@@]12([H])NCCO[C@@]1([H])CCC2.Cl

Computed Properties

  • Exact Mass: 163.0763918g/mol
  • Monoisotopic Mass: 163.0763918g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 10
  • Rotatable Bond Count: 0
  • Complexity: 105
  • Covalently-Bonded Unit Count: 2
  • Defined Atom Stereocenter Count: 2
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 21.3?2

(4aS,7aS)-Octahydrocyclopenta[b][1,4]oxazine hydrochloride Pricemore >>

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Additional information on (4aS,7aS)-Octahydrocyclopenta[b][1,4]oxazine hydrochloride

Comprehensive Overview of (4aS,7aS)-Octahydrocyclopenta[b][1,4]oxazine hydrochloride (CAS No. 1660110-86-0)

(4aS,7aS)-Octahydrocyclopenta[b][1,4]oxazine hydrochloride (CAS No. 1660110-86-0) is a chemically synthesized compound that has garnered significant attention in pharmaceutical and biochemical research. This bicyclic structure, characterized by its octahydrocyclopenta[b][1,4]oxazine core, is a key intermediate in the development of novel therapeutic agents. Researchers are particularly interested in its potential applications due to its unique stereochemistry and functional group compatibility, which make it a versatile building block in medicinal chemistry.

The compound's hydrochloride salt form enhances its solubility and stability, making it suitable for various experimental and industrial applications. Recent studies have explored its role in modulating biological targets, particularly in the central nervous system (CNS). Given the growing demand for CNS-targeting drugs, (4aS,7aS)-Octahydrocyclopenta[b][1,4]oxazine hydrochloride is being investigated for its potential in treating neurological disorders, such as anxiety and depression, which are among the most searched health topics globally.

From a synthetic perspective, the compound's stereospecific configuration (4aS,7aS) is critical for its biological activity. This specificity aligns with the increasing focus on chiral molecules in drug discovery, as enantiopure compounds often exhibit superior efficacy and reduced side effects. The pharmaceutical industry's shift toward precision medicine has further amplified the demand for such high-purity intermediates, positioning CAS No. 1660110-86-0 as a valuable asset in modern drug development pipelines.

In addition to its pharmaceutical relevance, (4aS,7aS)-Octahydrocyclopenta[b][1,4]oxazine hydrochloride is also a subject of interest in green chemistry initiatives. Researchers are exploring sustainable synthesis routes to minimize environmental impact, a topic highly searched by academic and industrial chemists alike. The compound's potential for catalytic asymmetric synthesis is another area of active investigation, addressing the need for eco-friendly and cost-effective production methods.

Analytical techniques such as NMR spectroscopy, HPLC, and mass spectrometry are routinely employed to characterize CAS No. 1660110-86-0, ensuring its purity and consistency. These methods are frequently searched by quality control professionals and researchers, reflecting the compound's importance in high-stakes applications. Furthermore, the rise of AI-driven drug discovery has spurred interest in predictive modeling for compounds like this, with machine learning algorithms being used to optimize its synthetic pathways and biological interactions.

As the scientific community continues to explore the untapped potential of (4aS,7aS)-Octahydrocyclopenta[b][1,4]oxazine hydrochloride, its role in advancing personalized therapeutics and biocompatible materials is becoming increasingly evident. With ongoing research and development, this compound is poised to contribute significantly to breakthroughs in both healthcare and sustainable chemistry, addressing some of the most pressing challenges in these fields.

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