Cas no 16596-41-1 (pyrrolidin-1-amine)

Pyrrolidin-1-amine is a secondary amine featuring a pyrrolidine ring, a five-membered saturated heterocycle with nitrogen. This compound is valued in organic synthesis and pharmaceutical research due to its structural versatility and nucleophilic properties. The pyrrolidine scaffold enhances molecular rigidity and bioavailability, making it a useful intermediate in drug design, particularly for bioactive molecules targeting CNS disorders. Its secondary amine functionality allows for further derivatization, enabling the introduction of diverse substituents. The compound’s stability and solubility in common organic solvents facilitate its handling in synthetic applications. Pyrrolidin-1-amine is often employed in the development of catalysts, ligands, and small-molecule therapeutics.
pyrrolidin-1-amine structure
pyrrolidin-1-amine structure
Product Name:pyrrolidin-1-amine
CAS No:16596-41-1
MF:C4H10N2
MW:86.135600566864
MDL:MFCD00003172
CID:50467
PubChem ID:27946
Update Time:2025-05-20

pyrrolidin-1-amine Chemical and Physical Properties

Names and Identifiers

    • 1-AMINOPYRROLIDINE
    • 1-Pyrrolidinamine
    • 1-AMINOPYRROLIDINE HYDROCHLORIDE
    • N-Aminopyrrolidine
    • Pyrrolidin-1-amine
    • Nsc80647
    • Pyrrolidine, 1-amino-
    • 1-AMINO TETRAHYDROPYRROLE
    • pyrrolidin-1-aMine hydrochloride
    • aminopyrrolidine
    • pyrrolidineamine
    • SBMSLRMNBSMKQC-UHFFFAOYSA-N
    • (3R)-(+)-Aminopyrrolidine
    • Jsp001762
    • Jsp001159
    • RP18467
    • TL8007049
    • ST24049089
    • BB 0218179
    • A810683
    • 596A411
    • Pyrrolidin-1-ylamine
    • FT-0601174
    • NSC 80647
    • DF424U7HM6
    • DTXSID40168052
    • EN300-201007
    • NSC-80647
    • A26943
    • AKOS003582850
    • F13227
    • 16596-41-1
    • UNII-DF424U7HM6
    • J-524150
    • MFCD07368381
    • pyrrolidylamine
    • P2560
    • DTXCID5090543
    • ALBB-032445
    • 1-Aminopyrrolidine?
    • Pyrrolidine, 1amino
    • DB-005671
    • SY235166
    • pyrrolidin-1-amine
    • MDL: MFCD00003172
    • Inchi: 1S/C4H10N2/c5-6-3-1-2-4-6/h1-5H2
    • InChI Key: SBMSLRMNBSMKQC-UHFFFAOYSA-N
    • SMILES: N1(CCCC1)N

Computed Properties

  • Exact Mass: 86.08440
  • Monoisotopic Mass: 86.084
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 6
  • Rotatable Bond Count: 0
  • Complexity: 38.8
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: nothing
  • XLogP3: -0.6
  • Topological Polar Surface Area: 29.3

Experimental Properties

  • Density: 0.986
  • Boiling Point: 30°C/13mmHg(lit.)
  • Flash Point: 28.1 °C
  • Refractive Index: 1.497
  • PSA: 29.26000
  • LogP: 0.59410

pyrrolidin-1-amine Security Information

pyrrolidin-1-amine Customs Data

  • HS CODE:2933990090
  • Customs Data:

    China Customs Code:

    2933990090

    Overview:

    2933990090. Other heterocyclic compounds containing only nitrogen heteroatoms. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

    Summary:

    2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

pyrrolidin-1-amine Pricemore >>

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pyrrolidin-1-amine Suppliers

Amadis Chemical Company Limited
Gold Member
Audited Supplier Audited Supplier
(CAS:16596-41-1)pyrrolidin-1-amine
Order Number:A26943
Stock Status:in Stock
Quantity:1g
Purity:99%
Pricing Information Last Updated:Monday, 2 September 2024 16:03
Price ($):526.0

pyrrolidin-1-amine Related Literature

Additional information on pyrrolidin-1-amine

Pyrrolidin-1-Amine: A Comprehensive Overview

Pyrrolidin-1-amine, also known by its CAS number 16596-41-1, is a versatile chemical compound that has garnered significant attention in various fields of chemistry and materials science. This compound, with the molecular formula C5H9N, belongs to the class of cyclic amines and is characterized by its five-membered ring structure containing one nitrogen atom. The compound's unique properties, including its ability to act as a building block in organic synthesis and its potential applications in drug discovery, make it a subject of ongoing research.

Recent studies have highlighted the role of pyrrolidin-1-amine in the development of novel materials and pharmaceuticals. For instance, researchers have explored its use as a precursor in the synthesis of bioactive molecules, particularly in the field of medicinal chemistry. The compound's ability to undergo various reactions, such as alkylation and acylation, has made it a valuable intermediate in the production of complex organic compounds. Moreover, its application in polymer chemistry has been explored, with findings suggesting its potential as a monomer in the synthesis of advanced polymeric materials.

The synthesis of pyrrolidin-1-amine has been optimized through innovative methodologies, ensuring higher yields and better purity. One notable advancement involves the use of catalytic hydrogenation techniques, which have significantly improved the efficiency of its production process. These improvements not only enhance the economic viability of large-scale production but also contribute to environmental sustainability by reducing waste and energy consumption.

In terms of applications, pyrrolidin-1-amine has found utility in diverse industries. In pharmaceuticals, it serves as an intermediate in the synthesis of various drugs, including antiviral agents and anticancer compounds. Its role as a chiral auxiliary has also been pivotal in asymmetric synthesis, enabling the production of enantiomerically pure compounds—a critical requirement in drug development.

Furthermore, recent research has delved into the use of pyrrolidin-1-amine in nanotechnology. Studies have demonstrated its potential as a stabilizing agent for nanoparticles, enhancing their stability and functionality. This opens up new avenues for its application in fields such as drug delivery systems and catalysis.

The compound's compatibility with various reaction conditions makes it an ideal candidate for exploring green chemistry principles. Researchers have investigated its use under mild reaction conditions, reducing the need for hazardous solvents and reagents. Such approaches align with global efforts to promote sustainable chemical practices.

In conclusion, pyrrolidin-1-amine (CAS No. 16596-41-1) stands out as a multifaceted compound with vast potential across multiple disciplines. Its role as a key intermediate in organic synthesis, coupled with its emerging applications in nanotechnology and green chemistry, underscores its importance in contemporary scientific research. As advancements continue to unfold, this compound is poised to play an even more significant role in shaping future innovations.

Recommended suppliers
Amadis Chemical Company Limited
(CAS:16596-41-1)pyrrolidin-1-amine
A26943
Purity:99%
Quantity:1g
Price ($):526.0
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