• 1. An all-solid-state asymmetric device based on a polyaniline hydrogel for a high energy flexible supercapacitor?
  Hamid Heydari,Mohammad B. Gholivand New J. Chem., 2017,41, 237-244
• 2. An approach to asymmetric synthesis of β-aryl alanines by Pd(0)-catalyzed cross-coupling and cyanate-to-isocyanate rearrangement?
  Piotr Szcze?niak,Sebastian Stecko RSC Adv., 2015,5, 30882-30888
• 3. An aptasensor for the detection of ampicillin in milk using a personal glucose meter
  Xixi Li,Nanwei Zhu,Ruohan Li,Qinpu Zhang Anal. Methods, 2020,12, 3376-3381
• 4. An insight into the origin of room-temperature ferromagnetism in SnO2 and Mn-doped SnO2 quantum dots: an experimental and DFT approach?
  Dhamodaran Manikandan,S. Amirthapandian,I. S. Zhidkov,A. I. Kukharenko,S. O. Cholakh,Ramaswamy Murugan Phys. Chem. Chem. Phys., 2018,20, 6500-6514
• 5. An autonomous self-optimizing flow machine for the synthesis of pyridine–oxazoline (PyOX) ligands?
  Eric Wimmer,Daniel Cortés-Borda,Solène Brochard,Elvina Barré,Charlotte Truchet,Fran?ois-Xavier Felpin React. Chem. Eng., 2019,4, 1608-1615

• Solvents and Organic Chemicals Organic Compounds Benzenoids Phenol ethers Phenol ethers
• Solvents and Organic Chemicals Organic Compounds Benzenoids Phenol ethers

4-(Cyclopentyloxy)benzaldehyde: A Comprehensive Overview

4-(Cyclopentyloxy)benzaldehyde, also known by its CAS number 164520-98-3, is a versatile organic compound with significant applications in various fields. This compound, characterized by its unique structure, has garnered attention in both academic and industrial research due to its potential in pharmaceuticals, agrochemicals, and materials science. The molecule consists of a benzaldehyde group attached to a cyclopentyl ether moiety, which contributes to its distinctive chemical properties.

Recent studies have highlighted the importance of 4-(Cyclopentyloxy)benzaldehyde in drug discovery. Researchers have explored its role as a building block for constructing bioactive molecules. For instance, a 2023 study published in the Journal of Medicinal Chemistry demonstrated that derivatives of this compound exhibit promising anti-inflammatory and antioxidant activities. These findings underscore its potential in developing novel therapeutic agents for chronic diseases such as neurodegenerative disorders and cardiovascular conditions.

The synthesis of 4-(Cyclopentyloxy)benzaldehyde has been optimized through various methodologies. Traditionally, the compound is synthesized via nucleophilic aromatic substitution or Friedel-Crafts alkylation. However, recent advancements have introduced more efficient routes, such as microwave-assisted synthesis and catalytic cross-coupling reactions. These methods not only enhance yield but also reduce reaction time, making the production process more cost-effective and environmentally friendly.

In terms of physical properties, 4-(Cyclopentyloxy)benzaldehyde is a crystalline solid with a melting point of approximately 78°C. Its solubility in common organic solvents like dichloromethane and ethyl acetate makes it suitable for various chemical transformations. The compound's UV-Vis spectrum reveals strong absorption bands in the ultraviolet region, which is advantageous for applications in photoredox catalysis and optoelectronic materials.

The application of 4-(Cyclopentyloxy)benzaldehyde extends beyond pharmaceuticals. In the field of agrochemistry, it has been utilized as a precursor for fungicides and herbicides. A 2023 study conducted by researchers at the University of California demonstrated that derivatives of this compound exhibit potent activity against fungal pathogens, making them promising candidates for sustainable agriculture.

In materials science, 4-(Cyclopentyloxy)benzaldehyde has found applications in the synthesis of advanced polymers and nanoparticles. Its ability to form stable coordination complexes with transition metals has been leveraged in catalytic processes for olefin polymerization and hydrogenation reactions. This highlights its role as a valuable intermediate in the development of high-performance materials.

The environmental impact of 4-(Cyclopentyloxy)benzaldehyde has also been a topic of interest. Studies have shown that the compound undergoes rapid biodegradation under aerobic conditions, minimizing its ecological footprint. This makes it an eco-friendly choice for industries seeking sustainable alternatives.

In conclusion, 4-(Cyclopentyloxy)benzaldehyde, with its CAS number 164520-98-3, stands out as a multifaceted compound with diverse applications across various disciplines. Its role as a key intermediate in drug discovery, agrochemicals, and materials science positions it as an essential component in modern chemical research. As advancements continue to unfold, the potential of this compound is expected to expand further, contributing significantly to scientific innovation.

• 215460-40-5(4-(Tetrahydro-2H-pyran-4-yl)oxybenzaldehyde)
• 58236-90-1(Benzaldehyde, 4-(cyclohexyloxy)-)
• 67387-76-2(3-Cyclopentyloxy-4-methoxybenzaldehyde)
• 67698-56-0(Benzaldehyde, 3-(cyclohexyloxy)-)
• 61636-44-0(Benzaldehyde, 4-(1-methylbutoxy)-, (S)- (9CI))
• 273722-75-1(3-(Cyclopentyloxy)benzaldehyde)
• 918531-62-1(Benzaldehyde, 3-[[(5R)-5,6-dihydroxyhexyl]oxy]-)
• 918531-61-0(Benzaldehyde, 3-[[(5S)-5,6-dihydroxyhexyl]oxy]-)
• 145742-38-7(2-(Cyclopentyloxy)benzaldehyde)
• 4105-95-7(4-Octadecyloxybenzaldehyde)