Cas no 1638744-12-3 ((1S)-2,2-Difluorocyclohexan-1-amine hydrochloride)

(1S)-2,2-Difluorocyclohexan-1-amine hydrochloride is a chiral amine derivative featuring a difluorinated cyclohexane backbone. Its stereospecific (1S) configuration ensures high enantiopurity, making it valuable for asymmetric synthesis and pharmaceutical applications. The difluorination enhances metabolic stability and lipophilicity, while the hydrochloride salt improves solubility and handling. This compound serves as a versatile intermediate in medicinal chemistry, particularly for developing bioactive molecules targeting CNS disorders or enzyme inhibition. Its rigid cyclohexane structure contributes to conformational control in drug design. The product is typically supplied as a white crystalline solid with well-characterized purity, suitable for research and industrial-scale applications requiring precise stereochemical control.

(1S)-2,2-Difluorocyclohexan-1-amine hydrochloride structure

1638744-12-3 structure

Product Name:(1S)-2,2-Difluorocyclohexan-1-amine hydrochloride

CAS No:1638744-12-3

MF:C₆H₁₂ClF₂N

MW:171.61598777771

MDL:MFCD28502321

CID:3165374

PubChem ID:92131084

Update Time:2025-10-29

(1S)-2,2-Difluorocyclohexan-1-amine hydrochloride Chemical and Physical Properties

Names and Identifiers

- (1S)-2,2-Difluorocyclohexan-1-amine hydrochloride
- 1638744-12-3
- (1S)-2,2-Difluorocyclohexan-1-amine HCl
- AKOS030628502
- (1S)-2,2-difluorocyclohexan-1-amine;hydrochloride
- P15787
- Cyclohexanamine, 2,2-difluoro-, hydrochloride (1:1), (1S)-
- MFCD28502321
- AS-52841
- (S)-2,2-Difluorocyclohexanaminehydrochloride
- CS-0053587
- (S)-2,2-Difluorocyclohexanamine hydrochloride
- EN300-7383467
- 889-151-9
- MDL： MFCD28502321
- Inchi： 1S/C6H11F2N.ClH/c7-6(8)4-2-1-3-5(6)9;/h5H,1-4,9H2;1H/t5-;/m0./s1
- InChI Key： INIHWKPDAPMHQD-JEDNCBNOSA-N
- SMILES： Cl.FC1(CCCC[C@@H]1N)F

Computed Properties

Exact Mass: 171.0626334g/mol
Monoisotopic Mass: 171.0626334g/mol
Isotope Atom Count: 0
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 3
Heavy Atom Count: 10
Rotatable Bond Count: 0
Complexity: 103
Covalently-Bonded Unit Count: 2
Defined Atom Stereocenter Count: 1
Undefined Atom Stereocenter Count : 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Topological Polar Surface Area: 26?2

(1S)-2,2-Difluorocyclohexan-1-amine hydrochloride Security Information

Signal Word：warning
Hazard Statement： H303+H313+H333
Warning Statement： P264+P280+P305+P351+P338+P337+P313
Safety Instruction： H303+H313+H333
Storage Condition：storage at -4℃ (1-2weeks), longer storage period at -20℃ (1-2years)

(1S)-2,2-Difluorocyclohexan-1-amine hydrochloride Pricemore >>

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