Cas no 163266-04-4 (1,1-Cyclopropanedicarboxylicacid, 2-fluoro-)

1,1-Cyclopropanedicarboxylic acid, 2-fluoro- is a fluorinated cyclopropane derivative with a dicarboxylic acid functional group. This compound is of interest in synthetic and medicinal chemistry due to its rigid cyclopropane ring and the presence of both fluorine and carboxylic acid moieties, which enhance its utility as a building block for bioactive molecules. The fluorine substitution can influence electronic and steric properties, potentially improving binding affinity or metabolic stability in drug design. Its dicarboxylic acid structure also allows for versatile derivatization, making it valuable for constructing complex frameworks. The compound is typically used in research settings for developing pharmaceuticals, agrochemicals, or advanced materials.
1,1-Cyclopropanedicarboxylicacid, 2-fluoro- structure
163266-04-4 structure
Product Name:1,1-Cyclopropanedicarboxylicacid, 2-fluoro-
CAS No:163266-04-4
MF:C5H5FO4
MW:148.089205503464
CID:110173
PubChem ID:45084707
Update Time:2025-10-28

1,1-Cyclopropanedicarboxylicacid, 2-fluoro- Chemical and Physical Properties

Names and Identifiers

    • 1,1-Cyclopropanedicarboxylicacid, 2-fluoro-
    • 2-Fluorocyclopropane-1,1-dicarboxylic acid
    • 1,1-Cyclopropanedicarboxylicacid,2-fluoro-(9CI)
    • 2-Fluorocyclopropane-1,1-dicarboxylicacid
    • AKOS025213695
    • MFCD18804404
    • DTXSID70665665
    • 163266-04-4
    • MDL: MFCD18804404
    • Inchi: 1S/C5H5FO4/c6-2-1-5(2,3(7)8)4(9)10/h2H,1H2,(H,7,8)(H,9,10)
    • InChI Key: FKEMAYUZSSPUGG-UHFFFAOYSA-N
    • SMILES: FC1CC1(C(=O)O)C(=O)O

Computed Properties

  • Exact Mass: 148.017
  • Monoisotopic Mass: 148.017
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 10
  • Rotatable Bond Count: 2
  • Complexity: 186
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 1
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 74.6A^2
  • XLogP3: -0.1

1,1-Cyclopropanedicarboxylicacid, 2-fluoro- Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
Chemenu
CM319343-1g
2-Fluorocyclopropane-1,1-dicarboxylic acid
163266-04-4 95%
1g
$845 2021-06-15
Chemenu
CM319343-1g
2-Fluorocyclopropane-1,1-dicarboxylic acid
163266-04-4 95%
1g
$845 2023-02-17

1,1-Cyclopropanedicarboxylicacid, 2-fluoro- Related Literature

Additional information on 1,1-Cyclopropanedicarboxylicacid, 2-fluoro-

1,1-Cyclopropanedicarboxylic Acid, 2-Fluoro-

1,1-Cyclopropanedicarboxylic acid, 2-fluoro- (CAS No. 163266-04-4) is a unique organic compound that has garnered significant attention in the fields of chemistry and materials science. This compound is characterized by its cyclopropane ring structure, which is a three-membered ring of carbon atoms, and the presence of two carboxylic acid groups attached to the same carbon atom. The fluorine atom at the 2-position further adds to its structural complexity and functional diversity.

The synthesis of 1,1-cyclopropanedicarboxylic acid, 2-fluoro- involves advanced organic chemistry techniques. Recent studies have focused on optimizing the synthesis pathways to enhance yield and purity. For instance, researchers have explored the use of transition metal catalysts to facilitate the formation of the cyclopropane ring. These advancements have not only improved the synthesis process but also opened new avenues for exploring its potential applications.

One of the most intriguing aspects of this compound is its physical and chemical properties. The cyclopropane ring introduces significant ring strain, which can influence its reactivity and stability. The presence of two carboxylic acid groups makes it highly polar and capable of forming hydrogen bonds, which is advantageous in various chemical reactions and material applications. Additionally, the fluorine atom at the 2-position imparts electronic effects that can modulate the compound's reactivity and solubility.

Recent research has highlighted the potential of 1,1-cyclopropanedicarboxylic acid, 2-fluoro- in materials science. Its unique structure makes it a promising candidate for designing novel polymers and coatings. For example, studies have shown that this compound can be used as a building block for synthesizing high-performance polymers with improved mechanical properties. The fluorine atom further enhances the polymer's resistance to environmental factors such as UV radiation and moisture.

In addition to materials science, this compound has also found applications in pharmaceutical research. The carboxylic acid groups and fluorine atom provide opportunities for designing bioactive molecules with specific pharmacological properties. Recent studies have explored its potential as a precursor for synthesizing drugs targeting specific biological pathways. The compound's ability to form stable complexes with metal ions has also been investigated for its potential in drug delivery systems.

The environmental impact of 1,1-cyclopropanedicarboxylic acid, 2-fluoro- has also been a topic of interest. Researchers have evaluated its biodegradability and toxicity under various conditions. Initial findings suggest that the compound exhibits moderate biodegradability under aerobic conditions, which is a positive indicator for its environmental safety. However, further studies are needed to fully understand its long-term impact on ecosystems.

Looking ahead, the development of novel applications for 1,1-cyclopropanedicarboxylic acid, 2-fluoro- is expected to continue at a rapid pace. Its unique combination of structural features makes it a versatile building block for various chemical industries. As research progresses, new insights into its properties and applications are likely to emerge, solidifying its position as an important compound in modern chemistry.

Recommended suppliers
Jinan Hanyu Chemical Co.,Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Jinan Hanyu Chemical Co.,Ltd.
Wuhan Comings Biotechnology Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Wuhan Comings Biotechnology Co., Ltd.
Shanghai Pearlk Chemicals Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Beyond Pharmaceutical Co., Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
Inner Mongolia Xinhong Biological Technology Co., Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Inner Mongolia Xinhong Biological Technology Co., Ltd