Cas no 162885-01-0 ((±)-Epibatidine dihydrochloride)
(±)-Epibatidine dihydrochloride is a potent nicotinic acetylcholine receptor (nAChR) agonist, derived from the skin of the Epipedobates anthonyi frog. This compound is widely utilized in neuroscience research due to its high affinity for neuronal nAChRs, making it a valuable tool for studying receptor subtypes and their physiological roles. Its dihydrochloride salt form enhances solubility and stability, facilitating precise experimental applications. (±)-Epibatidine dihydrochloride is particularly useful in pharmacological studies investigating pain pathways, addiction mechanisms, and neurodegenerative disorders. The racemic mixture allows for broader exploration of stereochemical effects on receptor binding and activity. Researchers value its consistent bioactivity and reliability in electrophysiological and behavioral assays.
162885-01-0 structure
Product Name:(±)-Epibatidine dihydrochloride
CAS No:162885-01-0
MF:C11H15Cl3N2
MW:281.609199762344
CID:134958
PubChem ID:87802432
Update Time:2025-05-28
(±)-Epibatidine dihydrochloride Chemical and Physical Properties
Names and Identifiers
-
- 7-Azabicyclo[2.2.1]heptane,2-(6-chloro-3-pyridinyl)-, hydrochloride (1:2), (1R,2R,4S)-rel-
- (+/-)-EPIBATIDINE DIHYDROCHLORIDE
- (+/-)-EPIBATIDINE DIHYDROCHLORIDE HYDRATE
- exo-(±)-2-(6-Chloro-3-pyridinyl)-7-azabicyclo[2.2.1]heptane dihydrochloride hydrate
- (±)-Epibatidine dihydrochloride
- 162885-01-0
- (1S,2S,4R)-2-(6-Chloropyridin-3-yl)-7-azabicyclo[2.2.1]heptane;dihydrochloride
- (1R,2R,4S)-Rel-2-(6-chloro-3-pyridinyl)-7-azabicyclo[2.2.1]heptane, dihydrochloride
- E98777
- (+/-)-Epibatidine (hydrochloride)
- SCHEMBL5267259
-
- Inchi： 1S/C11H13ClN2.2ClH/c12-11-4-1-7(6-13-11)9-5-8-2-3-10(9)14-8;;/h1,4,6,8-10,14H,2-3,5H2;2*1H/t8-,9+,10+;;/m1../s1
- InChI Key： DGNNWUINALNROG-YDMPKLSESA-N
- SMILES： ClC1=CC=C(C=N1)[C@@H]1C[C@H]2CC[C@@H]1N2.Cl.Cl
Computed Properties
- Exact Mass: 280.03000
- Monoisotopic Mass: 280.03
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 3
- Hydrogen Bond Acceptor Count: 2
- Heavy Atom Count: 16
- Rotatable Bond Count: 1
- Complexity: 221
- Covalently-Bonded Unit Count: 3
- Defined Atom Stereocenter Count: 3
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 24.9A^2
Experimental Properties
- Solubility: DMSO: >4?mg/mL
- PSA: 24.92000
- LogP: 4.27570
(±)-Epibatidine dihydrochloride Security Information
- Hazardous Material transportation number：UN 2811 6.1/PG 1
- WGK Germany：3
- Hazard Category Code： 27/28
- Safety Instruction： 28-36/37-45
-
Hazardous Material Identification：
(±)-Epibatidine dihydrochloride Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Axon Medchem | 1076-5 mg |
(±)-Epibatidine dihydrochloride |
162885-01-0 | 99% | 5mg |
€95.00 | 2023-07-10 | |
| Axon Medchem | 1076-25 mg |
(±)-Epibatidine dihydrochloride |
162885-01-0 | 99% | 25mg |
€425.00 | 2023-07-10 | |
| MedChemExpress | HY-101078A-5mg |
(±)-Epibatidine dihydrochloride |
162885-01-0 | 5mg |
￥4450 | 2022-08-31 | ||
| MedChemExpress | HY-101078A-10mg |
(±)-Epibatidine dihydrochloride |
162885-01-0 | 10mg |
￥4600 | 2022-08-31 | ||
| 1PlusChem | 1P00AQB3-1mg |
(+/-)-EPIBATIDINE DIHYDROCHLORIDE |
162885-01-0 | ≥98% | 1mg |
$126.00 | 2024-06-19 | |
| 1PlusChem | 1P00AQB3-5mg |
(+/-)-EPIBATIDINE DIHYDROCHLORIDE |
162885-01-0 | ≥98% | 5mg |
$368.00 | 2024-06-19 | |
| A2B Chem LLC | AE99855-1mg |
(+/-)-EPIBATIDINE DIHYDROCHLORIDE |
162885-01-0 | ≥98% | 1mg |
$73.00 | 2024-04-20 | |
| A2B Chem LLC | AE99855-5mg |
(+/-)-EPIBATIDINE DIHYDROCHLORIDE |
162885-01-0 | 99% | 5mg |
$163.00 | 2024-04-20 | |
| A2B Chem LLC | AE99855-25mg |
(+/-)-EPIBATIDINE DIHYDROCHLORIDE |
162885-01-0 | 99% | 25mg |
$590.00 | 2024-04-20 | |
| Axon Medchem | 1076-5mg |
(±)-Epibatidine dihydrochloride |
162885-01-0 | 99% | 5mg |
€95.00 | 2025-03-06 |
(±)-Epibatidine dihydrochloride Related Literature
-
Hongxia Li,Aikifa Raza,Qiaoyu Ge,Jin-You Lu,TieJun Zhang Soft Matter, 2020,16, 6841-6849
-
Norihito Fukui,Keisuke Fujimoto,Hideki Yorimitsu,Atsuhiro Osuka Dalton Trans., 2017,46, 13322-13341
-
Yaling Zhang,Chunhui Dai,Shiwei Zhou,Bin Liu Chem. Commun., 2018,54, 10092-10095
-
Gloria Belén Ramírez-Rodríguez,José Manuel Delgado-López,Jaime Gómez-Morales CrystEngComm, 2013,15, 2206-2212
162885-01-0 ((±)-Epibatidine dihydrochloride) Related Products
- 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
- 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
- 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
- 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
- 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
- 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
- 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
- 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
- 1449132-38-0(3-Fluoro-5-(2-fluoro-5-methylbenzylcarbamoyl)benzeneboronic acid)
- 2034271-14-0(2-(1H-indol-3-yl)-N-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}acetamide)
Recommended suppliers
Shenzhen GeneSeqTools Bioscience & Technology Co. Ltd.
Gold Member
Audited Supplier
CN Supplier
Reagent
Hangzhou Cedareal Technology Co., Ltd.
Gold Member
Audited Supplier
CN Supplier
Bulk
Jinan Hanyu Chemical Co.,Ltd.
Gold Member
Audited Supplier
CN Supplier
Bulk
Zouping Mingyuan Import and Export Trading Co., Ltd
Gold Member
Audited Supplier
CN Supplier
Reagent
TAIXING JOXIN BIO-TEC CO.,LTD.
Gold Member
Audited Supplier
CN Supplier
Bulk
