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Comprehensive Guide to 1-(2-Methoxy-phenoxy)-3-piperazin-1-yl-propan-2-ol (CAS No. 162712-35-8): Properties, Applications, and Market Insights

1-(2-Methoxy-phenoxy)-3-piperazin-1-yl-propan-2-ol (CAS No. 162712-35-8) is a specialized organic compound that has garnered significant attention in pharmaceutical and chemical research. This compound, characterized by its unique molecular structure combining a methoxy-phenoxy group with a piperazine moiety, exhibits versatile properties that make it valuable in various applications. Researchers and industry professionals frequently search for information on its synthesis, pharmacological potential, and commercial availability, reflecting its growing importance in scientific and industrial circles.

The molecular formula of 1-(2-Methoxy-phenoxy)-3-piperazin-1-yl-propan-2-ol is C14H22N2O3, with a molecular weight of 266.34 g/mol. Its structure features a central propan-2-ol backbone, which is substituted at the 1-position by a 2-methoxy-phenoxy group and at the 3-position by a piperazin-1-yl group. This arrangement imparts both hydrophilic and lipophilic characteristics, enhancing its solubility profile and making it suitable for formulation in various delivery systems. The presence of the piperazine ring is particularly noteworthy, as this heterocycle is a common pharmacophore in many bioactive molecules, contributing to interactions with biological targets.

In recent years, there has been increasing interest in 1-(2-Methoxy-phenoxy)-3-piperazin-1-yl-propan-2-ol due to its potential pharmacological activities. Preliminary studies suggest that this compound may exhibit modulating effects on certain neurotransmitter systems, sparking investigations into its possible applications in neurological research. These properties align with current trends in drug discovery, where researchers are actively exploring novel piperazine-containing compounds for their therapeutic potential. The compound's structural features also make it a candidate for further derivatization, allowing medicinal chemists to explore structure-activity relationships and optimize desired biological effects.

The synthesis of 1-(2-Methoxy-phenoxy)-3-piperazin-1-yl-propan-2-ol typically involves multi-step organic reactions, with careful control of reaction conditions to ensure high yield and purity. Common synthetic routes may begin with the preparation of appropriate 2-methoxy-phenoxy precursors, followed by sequential introduction of the propan-2-ol spacer and piperazine moiety. Process optimization is crucial, as evidenced by frequent searches for "high-yield synthesis of 162712-35-8" and "purification methods for 1-(2-Methoxy-phenoxy)-3-piperazin-1-yl-propan-2-ol" in scientific literature databases. These search trends reflect the practical challenges researchers face in working with this compound.

From an industrial perspective, 1-(2-Methoxy-phenoxy)-3-piperazin-1-yl-propan-2-ol has shown promise as an intermediate in the production of more complex molecules. Its unique structural elements make it valuable for creating libraries of compounds for high-throughput screening programs. The pharmaceutical industry in particular has shown sustained interest in this compound, as indicated by patent filings and research publications. Market analysts note growing demand for such specialized building blocks, driven by expanding drug discovery efforts worldwide and the continuous search for novel chemical entities with improved pharmacological profiles.

Quality control and analytical characterization of 1-(2-Methoxy-phenoxy)-3-piperazin-1-yl-propan-2-ol are critical aspects of its handling. Standard analytical techniques including HPLC, NMR spectroscopy, and mass spectrometry are routinely employed to verify the identity and purity of this compound. These quality assurance measures are particularly important given the compound's potential use in research applications where precise chemical composition is essential. The importance of proper characterization is reflected in frequent searches for "analytical methods for CAS 162712-35-8" and "specifications of 1-(2-Methoxy-phenoxy)-3-piperazin-1-yl-propan-2-ol."

Storage and handling of 1-(2-Methoxy-phenoxy)-3-piperazin-1-yl-propan-2-ol require standard laboratory precautions. The compound should be kept in tightly sealed containers, protected from light and moisture, at controlled room temperature. While not classified as highly hazardous under normal handling conditions, appropriate personal protective equipment should be used when working with this chemical, in line with general laboratory safety protocols. These handling considerations are commonly addressed in safety data sheets, which are frequently requested by researchers working with this material.

The commercial availability of 1-(2-Methoxy-phenoxy)-3-piperazin-1-yl-propan-2-ol has expanded in recent years, with several specialty chemical suppliers offering this compound in various quantities and purity grades. Pricing and availability can vary depending on market demand and production capacity. Procurement specialists often search for "bulk suppliers of 162712-35-8" and "custom synthesis of 1-(2-Methoxy-phenoxy)-3-piperazin-1-yl-propan-2-ol," indicating the need for reliable sources of this material. The growing market for such specialized compounds reflects broader trends in chemical research and development.

Looking ahead, the future applications of 1-(2-Methoxy-phenoxy)-3-piperazin-1-yl-propan-2-ol appear promising. As research into its properties continues, new potential uses may emerge in various fields of chemistry and life sciences. The compound's versatility and the increasing understanding of its characteristics position it as a valuable tool for scientific innovation. Ongoing studies may reveal additional aspects of its behavior and potential applications, further enhancing its value to the research community and related industries.

• 24588-96-3(2-Propanol,1-(dipropylamino)-3-(2-phenoxyphenoxy)-)
• 53073-91-9(Piperazine, 1-[(2,3-dihydro-1,4-benzodioxin-2-yl)methyl]-, hydrochloride (1:2))
• 62501-74-0(Piperazine, 1-[(2,3-dihydro-1,4-benzodioxin-2-yl)methyl]-, (R)- (9CI))
• 58774-82-6(2-Propanol,1,1'-(1,2-ethanediyldiimino)bis[3-(2-ethoxyphenoxy)- (9CI))
• 7031-63-2(1-(2,3-dihydro-1,4-benzodioxin-2-yl)methylpiperazine)
• 62501-75-1(Piperazine, 1-[(2,3-dihydro-1,4-benzodioxin-2-yl)methyl]-, (S)- (9CI))
• 40944-05-6(1-phenoxy-3-(piperazin-1-yl)propan-2-ol)
• 100508-26-7(Piperazine,1-[(2,3-dihydro-1,4-benzodioxin-2-yl)methyl]-4-[2-(2-methoxyphenoxy)ethyl]-)
• 7762-32-5(1,4-bis(2,3-dihydro-1,4-benzodioxin-2-ylmethyl)piperazine)
• 66825-05-6(2-Propanol, 1-[(2-aminoethyl)amino]-3-(2-methoxyphenoxy)-)