Cas no 162227-13-6 (Hydroxy Terbinafine)
Hydroxy Terbinafine is a derivative of terbinafine, an allylamine antifungal agent. It exhibits enhanced solubility and bioavailability compared to its parent compound, making it particularly effective in topical and systemic antifungal formulations. The hydroxyl group modification improves its pharmacokinetic profile, allowing for better tissue penetration and sustained activity against dermatophytes, yeasts, and molds. Its mechanism of action involves inhibition of squalene epoxidase, disrupting ergosterol synthesis in fungal cell membranes. Hydroxy Terbinafine is valued for its broad-spectrum efficacy, reduced side effects, and compatibility with various delivery systems, making it suitable for treating cutaneous and superficial fungal infections.
Hydroxy Terbinafine structure
Product Name:Hydroxy Terbinafine
CAS No:162227-13-6
MF:C21H25NO
MW:307.429305791855
CID:109926
PubChem ID:21917706
Update Time:2025-10-19
Hydroxy Terbinafine Chemical and Physical Properties
Names and Identifiers
-
- 5-Hepten-3-yn-1-ol,2,2-dimethyl-7-[methyl(1-naphthalenylmethyl)amino]-, (5E)-
- Hydroxy Terbinafine
- (5E)
- (5E)-2,2-Dimethyl-7-[methyl(1-naphthalenylmethyl)amino]-5-hepten-3-yn-1-ol
- (5E)-
- NS00116746
- J-009906
- SCHEMBL3256605
- Hydroxyterbinafine
- 5-Hepten-3-yn-1-ol, 2,2-dimethyl-7-[methyl(1-naphthalenylmethyl)amino]-, (5E)-
- (E)-2,2-dimethyl-7-[methyl(naphthalen-1-ylmethyl)amino]hept-5-en-3-yn-1-ol
- SCHEMBL3256599
- CHEBI:174203
- 162227-13-6
- DB-257810
- (5E)-2,2-dimethyl-7-[methyl(1-naphthylmethyl)amino]-5-hepten-3-yn-1-ol
-
- Inchi： 1S/C21H25NO/c1-21(2,17-23)14-7-4-8-15-22(3)16-19-12-9-11-18-10-5-6-13-20(18)19/h4-6,8-13,23H,15-17H2,1-3H3/b8-4+
- InChI Key： GPEJUKJZTGFNKY-XBXARRHUSA-N
- SMILES： OCC(C#C/C=C/CN(C)CC1C=CC=C2C=CC=CC=12)(C)C
Computed Properties
- Exact Mass: 307.19400
- Monoisotopic Mass: 307.193614421g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 2
- Heavy Atom Count: 23
- Rotatable Bond Count: 6
- Complexity: 453
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 1
- Undefined Bond Stereocenter Count: 0
- XLogP3: 4.4
- Topological Polar Surface Area: 23.5?2
Experimental Properties
- Melting Point: N/A
- Solubility: Chloroform, Dichloromethane, Methanol
- PSA: 23.47000
- LogP: 3.84970
Hydroxy Terbinafine Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| TRC | H956160-1mg |
Hydroxy Terbinafine |
162227-13-6 | 1mg |
$ 221.00 | 2023-09-07 | ||
| TRC | H956160-10mg |
Hydroxy Terbinafine |
162227-13-6 | 10mg |
$ 1669.00 | 2023-09-07 | ||
| SHENG KE LU SI SHENG WU JI SHU | sc-207743-1 mg |
Hydroxy Terbinafine, |
162227-13-6 | 1mg |
￥3,234.00 | 2023-07-11 | ||
| SHENG KE LU SI SHENG WU JI SHU | sc-207743-1mg |
Hydroxy Terbinafine, |
162227-13-6 | 1mg |
￥3234.00 | 2023-09-05 | ||
| 1PlusChem | 1P001TCW-1mg |
5-Hepten-3-yn-1-ol, 2,2-dimethyl-7-[methyl(1-naphthalenylmethyl)amino]-, (5E)- |
162227-13-6 | 1mg |
$289.00 | 2025-02-19 | ||
| 1PlusChem | 1P001TCW-10mg |
5-Hepten-3-yn-1-ol, 2,2-dimethyl-7-[methyl(1-naphthalenylmethyl)amino]-, (5E)- |
162227-13-6 | 10mg |
$1421.00 | 2025-02-19 | ||
| A2B Chem LLC | AA83904-1mg |
5-Hepten-3-yn-1-ol, 2,2-dimethyl-7-[methyl(1-naphthalenylmethyl)amino]-, (5E)- |
162227-13-6 | 1mg |
$1207.00 | 2024-04-20 | ||
| A2B Chem LLC | AA83904-5mg |
5-Hepten-3-yn-1-ol, 2,2-dimethyl-7-[methyl(1-naphthalenylmethyl)amino]-, (5E)- |
162227-13-6 | 5mg |
$3050.00 | 2024-04-20 |
Hydroxy Terbinafine Related Literature
-
Aloke Das,K. K. Mahato,Chayan K. Nandi,Tapas Chakraborty,Shridhar R. Gadre,Nikhil A. Gokhale Phys. Chem. Chem. Phys., 2002,4, 2162-2168
-
Alexandre Vimont,Arnaud Travert,Philippe Bazin,Jean-Claude Lavalley,Marco Daturi,Christian Serre,Gérard Férey,Sandrine Bourrelly,Philip L. Llewellyn Chem. Commun., 2007, 3291-3293
-
Bruce Parkinson Energy Environ. Sci., 2010,3, 509-511
-
Xing Zhao,Lu Bai,Rui-Ying Bao,Zheng-Ying Liu,Ming-Bo Yang,Wei Yang RSC Adv., 2017,7, 46297-46305
-
Daniel Messmer,Stefan Salentinig,Jakob Heier Nanoscale, 2019,11, 6929-6938
162227-13-6 (Hydroxy Terbinafine) Related Products
- 91161-71-6(Terbinafine)
- 99473-11-7(N-Desmethyl Terbinafine)
- 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
- 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
- 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
- 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
- 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
- 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
- 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
- 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
Recommended suppliers
Jiangsu Xinsu New Materials Co., Ltd
Gold Member
Audited Supplier
CN Supplier
Bulk
Yunnanjiuzhen
Gold Member
Audited Supplier
CN Supplier
Bulk
Shandong Jing Kun Chemical Co.,Ltd.
Gold Member
Audited Supplier
CN Supplier
Bulk
Inner Mongolia Xinhong Biological Technology Co., Ltd
Gold Member
Audited Supplier
CN Supplier
Bulk
ASIACHEM I&E (JIANGSU) CO., LTD
Gold Member
Audited Supplier
CN Supplier
Bulk
