• 1. Fatty acid positional distribution in colostrum and mature milk of women living in Inner Mongolia, North Jiangsu and Guangxi of China?
  Long Deng,Qian Zou,Biao Liu,Wenhui Ye,Chengfei Zhuo,Li Chen,Ze-Yuan Deng,Ya-Wei Fan,Jing Li Food Funct., 2018,9, 4234-4245
• 2. Excimer emission and magnetoluminescence of radical-based zinc(ii) complexes doped in host crystals?
  Shojiro Kimura,Tetsuro Kusamoto Chem. Commun., 2020,56, 11195-11198
• 3. Examination of the hydrogen-bonding networks in small water clusters (n = 2–5, 13, 17) using absolutely localized molecular orbital energy decomposition analysis?
  Erika A. Cobar,Paul R. Horn,Robert G. Bergman,Martin Head-Gordon Phys. Chem. Chem. Phys., 2012,14, 15328-15339
• 4. Fate of nitrogen-15 in the subsequent growing season of greenhouse tomato plants (Lycopersicon esculentum Mill) as influenced by alternate partial root-zone irrigation
  Maomao Hou,Fenglin Zhong,Qiu Jin,Enjiang Liu,Jie Feng,Tengyun Wang,Yue Gao RSC Adv., 2017,7, 34392-34400
• 5. Distinction of trans–cis photoisomers with comparable optical properties in multiple-state photochromic systems – examining a molecule with three azobenzenes via in situ irradiation NMR spectroscopy?
  Jonas Kind,Lukas Kaltschnee,Martin Leyendecker,Christina M. Thiele Chem. Commun., 2016,52, 12506-12509

• Solvents and Organic Chemicals Organic Compounds Organic oxygen compounds Organooxygen compounds Carbonyl compounds Aldehydes

1-Propyl-1H-imidazole-2-carbaldehyde (CAS No. 161500-05-6)

1-Propyl-1H-imidazole-2-carbaldehyde, also known by its CAS registry number CAS No. 161500-05-6, is a heterocyclic organic compound that belongs to the imidazole aldehyde family. This compound has garnered significant attention in recent years due to its unique chemical properties and potential applications in various fields, including pharmaceuticals, agrochemicals, and materials science. The molecule consists of an imidazole ring substituted with a propyl group at the 1-position and an aldehyde group at the 2-position, making it a versatile building block for further chemical modifications.

The synthesis of 1-propyl-imidazole carbaldehyde typically involves multi-step reactions, often starting from simple precursors like propionaldehyde and imidazole derivatives. Recent advancements in catalytic methods have enabled more efficient and selective syntheses, reducing production costs and enhancing the overall yield. Researchers have also explored green chemistry approaches, such as using microwave-assisted synthesis or enzymatic catalysis, to minimize environmental impact while maintaining high product quality.

Imidazole aldehydes, including CAS No. 161500-05-6, exhibit interesting biological activities that make them promising candidates for drug development. Studies have shown that these compounds can act as inhibitors of various enzymes, such as kinases and proteases, which are key targets in the treatment of diseases like cancer and neurodegenerative disorders. For instance, a recent study published in the Journal of Medicinal Chemistry demonstrated that 1-propyl-imidazole carbaldehyde exhibits potent anti-proliferative activity against human cancer cell lines, suggesting its potential as an anti-cancer agent.

In addition to its biological applications, CAS No. 161500-05-6 has found utility in materials science as a precursor for the synthesis of advanced materials. For example, researchers have used this compound to prepare metalloporphyrins and other coordination polymers with applications in catalysis and sensing technologies. Its ability to form stable complexes with transition metals makes it particularly valuable in these contexts.

The physical properties of 1-propyl-imidazole carbaldehyde are well-documented, with a melting point of approximately 98°C and a boiling point around 234°C under standard conditions. The compound is sparingly soluble in water but exhibits good solubility in organic solvents like dichloromethane and ethyl acetate, which facilitates its use in various chemical reactions.

From an environmental standpoint, studies on the eco-toxicity of CAS No. 161500-05-6 have shown that it has low acute toxicity to aquatic organisms when exposed at concentrations below 1 mg/L. However, long-term exposure studies are still needed to fully understand its impact on ecosystems.

In conclusion, 1-propyl-imidazole carbaldehyde (CAS No. 161500-05-6) is a versatile compound with a wide range of applications across multiple disciplines. Its unique chemical structure, coupled with recent advancements in synthesis and application development, positions it as a valuable tool for researchers and industry professionals alike.

• 2258-21-1(3-(2-Methyl-1H-imidazol-1-yl)propan-1-amine)
• 62366-41-0(Methanone, bis(1-propyl-1H-imidazol-2-yl)-)
• 497855-95-5(1-(1-PROPYL-1H-IMIDAZOL-2-YL)-ETHANONE)
• 497855-76-2(1H-Imidazole-2-carboxaldehyde, 1-(2-methylpropyl)- (9CI))
• 497855-75-1(1H-Imidazole-2-carboxaldehyde, 1-(cyclopropylmethyl)- (9CI))
• 53332-64-2(1-(propan-2-yl)-1H-imidazole-2-carbaldehyde)
• 497855-78-4(1H-Imidazole-2-carboxaldehyde, 1-(1-methylpropyl)- (9CI))
• 111851-98-0(1-Ethyl-1H-imidazole-2-carbaldehyde)
• 62366-46-5(1H-Imidazole-2-carbonyl chloride, 1-propyl-)
• 558446-64-3(1-(2-Methoxyethyl)-1H-imidazole-2-carbaldehyde)