Cas no 160893-07-2 (2-Chloro-5-methoxyquinoline)
2-Chloro-5-methoxyquinoline is a heterocyclic organic compound featuring a quinoline core substituted with a chloro group at the 2-position and a methoxy group at the 5-position. This structure imparts unique reactivity, making it a valuable intermediate in pharmaceutical and agrochemical synthesis. The chloro group enhances electrophilic substitution potential, while the methoxy moiety contributes to electronic modulation, improving selectivity in cross-coupling reactions. Its stability under various conditions allows for versatile applications in medicinal chemistry, particularly in the development of bioactive molecules. The compound's well-defined synthetic pathway ensures consistent purity, making it suitable for research and industrial-scale processes requiring precise functionalization of the quinoline scaffold.
2-Chloro-5-methoxyquinoline structure
Product Name:2-Chloro-5-methoxyquinoline
CAS No:160893-07-2
MF:C10H8ClNO
MW:193.629621505737
MDL:MFCD22394142
CID:1036268
PubChem ID:11019719
Update Time:2025-05-28
2-Chloro-5-methoxyquinoline Chemical and Physical Properties
Names and Identifiers
-
- 2-Chloro-5-methoxyquinoline
- 160893-07-2
- CS-0188166
- 5-methoxy-2-chloroquinoline
- A906471
- SB67686
- Quinoline, 2-chloro-5-methoxy-
- SY103261
- C73044
- DTXSID30452114
- SCHEMBL2242668
- EN300-3239346
- ACMDJXKHEUGSIS-UHFFFAOYSA-N
- AKOS016000790
- MFCD22394142
- DS-5932
-
- MDL: MFCD22394142
- Inchi: 1S/C10H8ClNO/c1-13-9-4-2-3-8-7(9)5-6-10(11)12-8/h2-6H,1H3
- InChI Key: ACMDJXKHEUGSIS-UHFFFAOYSA-N
- SMILES: ClC1=CC=C2C(=CC=CC2=N1)OC
Computed Properties
- Exact Mass: 193.0294416g/mol
- Monoisotopic Mass: 193.0294416g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 2
- Heavy Atom Count: 13
- Rotatable Bond Count: 1
- Complexity: 176
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 3.1
- Topological Polar Surface Area: 22.1?2
Experimental Properties
- Boiling Point: 310.5±22.0°C at 760 mmHg
2-Chloro-5-methoxyquinoline Security Information
- Signal Word:Warning
- Hazard Statement: H302-H315-H319-H335
- Warning Statement: P261-P305+P351+P338
- Storage Condition:Inert atmosphere,2-8°C
2-Chloro-5-methoxyquinoline Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd. | C893893-250mg |
2-Chloro-5-methoxyquinoline |
160893-07-2 | ≥95% | 250mg |
¥2,236.50 | 2022-09-29 | |
| TRC | C632243-10mg |
2-Chloro-5-methoxyquinoline |
160893-07-2 | 10mg |
$ 50.00 | 2022-06-06 | ||
| TRC | C632243-50mg |
2-Chloro-5-methoxyquinoline |
160893-07-2 | 50mg |
$ 185.00 | 2022-06-06 | ||
| TRC | C632243-100mg |
2-Chloro-5-methoxyquinoline |
160893-07-2 | 100mg |
$ 275.00 | 2022-06-06 | ||
| Alichem | A189005058-250mg |
2-Chloro-5-methoxyquinoline |
160893-07-2 | 95% | 250mg |
260.10 USD | 2021-06-01 | |
| Alichem | A189005058-1g |
2-Chloro-5-methoxyquinoline |
160893-07-2 | 95% | 1g |
650.76 USD | 2021-06-01 | |
| Alichem | A189005058-5g |
2-Chloro-5-methoxyquinoline |
160893-07-2 | 95% | 5g |
1,897.20 USD | 2021-06-01 | |
| Chemenu | CM142985-1g |
2-Chloro-5-methoxyquinoline |
160893-07-2 | 95% | 1g |
$597 | 2021-08-05 | |
| Chemenu | CM142985-5g |
2-Chloro-5-methoxyquinoline |
160893-07-2 | 95% | 5g |
$1739 | 2021-08-05 | |
| Chemenu | CM142985-250mg |
2-Chloro-5-methoxyquinoline |
160893-07-2 | 95% | 250mg |
$241 | 2023-02-17 |
2-Chloro-5-methoxyquinoline Related Literature
-
Saeideh Mirfakhraei,Malak Hekmati,Fereshteh Hosseini Eshbala,Hojat Veisi New J. Chem., 2018,42, 1757-1761
-
Shintaro Takata,Yoshihiro Miura Phys. Chem. Chem. Phys., 2014,16, 24784-24789
-
Xing Zhao,Lu Bai,Rui-Ying Bao,Zheng-Ying Liu,Ming-Bo Yang,Wei Yang RSC Adv., 2017,7, 46297-46305
-
Aloke Das,K. K. Mahato,Chayan K. Nandi,Tapas Chakraborty,Shridhar R. Gadre,Nikhil A. Gokhale Phys. Chem. Chem. Phys., 2002,4, 2162-2168
-
Norihito Fukui,Keisuke Fujimoto,Hideki Yorimitsu,Atsuhiro Osuka Dalton Trans., 2017,46, 13322-13341
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