• 1. Excimer formation effects and trap-assisted charge recombination loss channels in organic solar cells of perylene diimide dimer acceptors?
  Min Kim,Jae-Joon Lee,Tengling Ye,Panagiotis E. Keivanidis,Kilwon Cho J. Mater. Chem. C, 2020,8, 1686-1696
• 2. Esterase-responsive polymeric prodrug-based tumor targeting nanoparticles for improved anti-tumor performance against colon cancer?
  Gang Pan,Yi-jie Bao,Jie Xu,Tao Liu,Cheng Liu,Yan-yan Qiu,Xiao-jing Shi,Hui Yu,Ting-ting Jia,Xia Yuan,Ze-ting Yuan,Yi-jun Cao RSC Adv., 2016,6, 42109-42119
• 3. Emerging investigator series: heterogeneous reactions of sulfur dioxide on mineral dust nanoparticles: from single component to mixed components?
  Tao Wang,Yangyang Liu,Yue Deng,Hongbo Fu,Jianmin Chen Environ. Sci.: Nano, 2018,5, 1821-1833
• 4. Examination of the hydrogen-bonding networks in small water clusters (n = 2–5, 13, 17) using absolutely localized molecular orbital energy decomposition analysis?
  Erika A. Cobar,Paul R. Horn,Robert G. Bergman,Martin Head-Gordon Phys. Chem. Chem. Phys., 2012,14, 15328-15339
• 5. Fe3O4 nanoclusters highly dispersed on a porous graphene support as an additive for improving the hydrogen storage properties of LiBH4?
  Guang Xu,Wei Zhang,Ying Zhang,Xiaoxia Zhao,Ping Wen,Di Ma RSC Adv., 2018,8, 19353-19361

Chemical Profile of 2-Propanol, 1-bromo-, (2S) and Its CAS No. 16088-60-1

The compound 2-Propanol, 1-bromo-, (2S), identified by the CAS number 16088-60-1, is a significant chemical entity in the field of organic synthesis and pharmaceutical applications. This enantiomerically pure compound belongs to the class of brominated alcohols, which have garnered considerable attention due to their versatile reactivity and utility in synthetic chemistry. The stereochemical specification at the secondary carbon atom, denoted by the (2S) configuration, underscores its uniqueness and potential applications in asymmetric synthesis.

In recent years, the demand for enantiomerically pure intermediates has surged in the pharmaceutical industry, driven by the need for chiral drugs with enhanced efficacy and reduced side effects. The (2S)-configuration of 2-Propanol, 1-bromo-, (2S) makes it a valuable building block for constructing complex molecular architectures. Its bromo-substituted alcohol moiety allows for further functionalization via nucleophilic substitution reactions, cross-coupling reactions, and other organic transformations. These properties have positioned it as a key reagent in the synthesis of active pharmaceutical ingredients (APIs) and fine chemicals.

One of the most compelling aspects of 2-Propanol, 1-bromo-, (2S) is its role in enantioselective synthesis. The presence of a well-defined stereochemical center enables chemists to selectively construct one enantiomer over another, which is crucial for developing enantiomerically pure drugs. For instance, studies have demonstrated its utility in the synthesis of chiral auxiliaries and ligands that facilitate asymmetric hydrogenation and epoxidation reactions. These advancements highlight the compound's importance in modern synthetic methodologies.

Moreover, research has explored the applications of 2-Propanol, 1-bromo-, (2S) in medicinal chemistry. Its structural features make it a suitable precursor for developing novel therapeutic agents. For example, brominated alcohols have been investigated as intermediates in the synthesis of antiviral and anticancer compounds. The (2S)-enantiomer, in particular, has shown promise in generating pharmacologically active molecules with improved selectivity and potency. This has spurred further interest in its use as a starting material for drug discovery programs.

The industrial production of 2-Propanol, 1-bromo-, (2S) has also seen significant advancements. Modern synthetic routes leverage catalytic processes to enhance yield and purity while minimizing environmental impact. These innovations align with global trends toward sustainable chemistry practices. For instance, green chemistry principles have been applied to optimize bromination reactions, reducing waste and energy consumption. Such developments not only improve cost efficiency but also contribute to a more sustainable chemical industry.

Recent studies have also delved into the mechanistic aspects of reactions involving 2-Propanol, 1-bromo-, (2S). Understanding these reaction pathways is essential for designing efficient synthetic strategies and predicting product outcomes. Computational chemistry has played a pivotal role in elucidating these mechanisms at an atomic level. By leveraging advanced computational methods, researchers can identify optimal reaction conditions and predict the stereochemical outcomes with high accuracy.

The versatility of 2-Propanol, 1-bromo-, (2S) extends beyond pharmaceutical applications into materials science and agrochemicals. Its reactivity allows for the creation of functionalized polymers and specialty chemicals with tailored properties. For example, bromo-alcohols have been used to modify polymer backbones, enhancing their thermal stability or biodegradability. Similarly, in agrochemistry, derivatives of this compound have been explored as intermediates for developing new pesticides with improved environmental profiles.

In conclusion,2-Propanol, 1-bromo-, (2S) identified by CAS number 16088-60-1, represents a cornerstone compound in organic synthesis with far-reaching implications across multiple industries. Its unique stereochemical configuration and reactivity make it indispensable for constructing chiral molecules essential for drug development. As research continues to uncover new applications and synthetic methodologies,this compound will undoubtedly remain at the forefront of chemical innovation.

• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
• 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
• 1449132-38-0(3-Fluoro-5-(2-fluoro-5-methylbenzylcarbamoyl)benzeneboronic acid)
• 2034271-14-0(2-(1H-indol-3-yl)-N-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}acetamide)