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  Luis Miguel Azofra,Douglas R. MacFarlane,Chenghua Sun Chem. Commun., 2016,52, 3548-3551
• 2. An atomistic mechanism for the degradation of perovskite solar cells by trapped charge?
  Eunhak Lim,Jiyoung Heo,Seong Keun Kim Nanoscale, 2019,11, 11369-11378
• 3. An assay for the enzyme N-acetyl-β-d-glucosaminidase (NAGase) based on electrochemical detection using screen-printed carbon electrodes (SPCEs)
  R. M. Pemberton,J. P. Hart,T. T. Mottram Analyst, 2001,126, 1866-1871
• 4. An integrated microfluidic platform for sensitive and rapid detection of biological toxins?
  Robert J. Meagher,Anson V. Hatch,Ronald F. Renzi,Anup K. Singh Lab Chip, 2008,8, 2046-2053
• 5. An artificial blood vessel implanted three-dimensional microsystem for modeling transvascular migration of tumor cells?
  Xue-Ying Wang,Ying Pei,Min Xie,Zi-He Jin,Ya-Shi Xiao,Yang Wang,Li-Na Zhang,Yan Li,Wei-Hua Huang Lab Chip, 2015,15, 1178-1187

• Solvents and Organic Chemicals Organic Compounds Organic nitrogen compounds Organonitrogen compounds Nitriles
• Solvents and Organic Chemicals Organic Compounds Organic nitrogen compounds Organonitrogen compounds Organic cyanides Nitriles

Comprehensive Analysis of 2-(2-methylcyclopropyl)acetonitrile (CAS No. 159045-22-4): Properties, Applications, and Industry Insights

2-(2-methylcyclopropyl)acetonitrile (CAS No. 159045-22-4) is a specialized organic compound with a unique cyclopropyl structure, making it a valuable intermediate in pharmaceutical and fine chemical synthesis. Its molecular formula, C₆H₉N, and distinct nitrile functional group contribute to its reactivity, enabling diverse applications in modern chemistry. This article explores its properties, synthesis methods, and emerging trends, addressing key questions like "What is 2-(2-methylcyclopropyl)acetonitrile used for?" and "How is CAS 159045-22-4 synthesized?"—topics frequently searched in academic and industrial circles.

The compound’s methylcyclopropyl moiety enhances its steric and electronic properties, which are critical for designing bioactive molecules. Researchers often investigate "2-(2-methylcyclopropyl)acetonitrile solubility" and "stability under different conditions," as these factors influence its utility in multi-step reactions. Recent studies highlight its role in developing non-toxic agrochemicals and sustainable materials, aligning with global demands for greener alternatives. For instance, its derivatization into biodegradable polymers has gained attention in circular economy discussions.

From a synthetic perspective, 159045-22-4 is typically produced via nucleophilic substitution or catalytic cyanation of precursor halides. Optimizing yield and purity remains a focus, as reflected in searches like "high-purity 2-(2-methylcyclopropyl)acetonitrile suppliers." Analytical techniques such as GC-MS and NMR spectroscopy are essential for quality control, ensuring compliance with industry standards like REACH and GMP.

The compound’s versatility extends to flavor and fragrance applications, where its nitrile group can be hydrolyzed to carboxylic acids or reduced to amines. This adaptability answers queries such as "How to modify 2-(2-methylcyclopropyl)acetonitrile for fragrance use?"—a niche yet growing area. Additionally, its potential in electronic materials, particularly as a precursor for conductive polymers, is under exploration, tapping into the booming flexible electronics market.

Regulatory and safety profiles of CAS 159045-22-4 are rigorously documented, with data sheets emphasizing proper handling to avoid irritation. However, its classification as non-hazardous under normal conditions makes it preferable for scalable processes. Environmental impact studies, including "biodegradation pathways of nitrile compounds," further support its sustainable profile.

In conclusion, 2-(2-methylcyclopropyl)acetonitrile exemplifies innovation at the intersection of chemistry and industry needs. Its relevance in drug discovery, green chemistry, and advanced materials ensures continued research interest. For professionals seeking "reliable CAS 159045-22-4 technical data" or "custom synthesis options," this compound offers a compelling case study in functional molecular design.

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