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• 2. Excellent energy storage performance in NaNbO3-based relaxor antiferroeic ceramics under a low electric field
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• 3. Emergence of cationic polyamine dendrimersomes: design, stimuli sensitivity and potential biomedical applications
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• Solvents and Organic Chemicals Organic Compounds Benzenoids Phenols Benzenediols Catechols
• Solvents and Organic Chemicals Organic Compounds Benzenoids Phenols Catechols

Introduction to 4-Aminobenzene-1,2-diol hydrobromide (CAS No. 158627-59-9)

4-Aminobenzene-1,2-diol hydrobromide, with the chemical formula C?H?BrNO?, is a brominated derivative of resorcinolamine. This compound has garnered significant attention in the field of pharmaceutical and medicinal chemistry due to its versatile structural properties and potential biological activities. The presence of both an amine and hydroxyl functional groups makes it a valuable intermediate in the synthesis of various pharmacologically active molecules.

The synthesis of 4-Aminobenzene-1,2-diol hydrobromide typically involves the bromination of resorcinolamine followed by hydrobromic acid treatment to form the corresponding hydrobromide salt. This process highlights the compound's synthetic utility and its role as a building block in organic chemistry. The hydrobromide form enhances the solubility and stability of the compound, making it more suitable for further chemical modifications and biological evaluations.

Recent research has demonstrated the potential of 4-Aminobenzene-1,2-diol hydrobromide in the development of novel therapeutic agents. Its structural motif is reminiscent of several known bioactive compounds, suggesting that it may exhibit similar pharmacological effects. For instance, studies have explored its role as a precursor in the synthesis of kinase inhibitors, which are crucial in targeting various cancers and inflammatory diseases. The amine group provides a site for further functionalization, allowing chemists to tailor the compound's properties for specific applications.

In addition to its kinase inhibition potential, 4-Aminobenzene-1,2-diol hydrobromide has been investigated for its antimicrobial properties. The combination of bromine and nitrogen-containing functionalities often confers broad-spectrum activity against bacteria and fungi. Preliminary in vitro studies have shown promising results, indicating that derivatives of this compound may serve as effective antimicrobial agents. This aligns with the growing need for new antibiotics to combat drug-resistant pathogens.

The pharmaceutical industry has also shown interest in 4-Aminobenzene-1,2-diol hydrobromide due to its potential role in central nervous system (CNS) drug development. The benzene ring and its substituents can interact with neurotransmitter receptors, making it a candidate for treating neurological disorders such as depression and anxiety. Further research is needed to fully elucidate its mechanisms of action, but early findings are encouraging.

From a chemical biology perspective, 4-Aminobenzene-1,2-diol hydrobromide serves as an important scaffold for studying enzyme interactions. Its ability to mimic natural substrates or inhibitors allows researchers to probe enzyme mechanisms at a molecular level. This has implications not only for drug discovery but also for understanding fundamental biological processes. The compound's versatility makes it a valuable tool in biochemical assays and high-throughput screening campaigns.

The industrial applications of 4-Aminobenzene-1,2-diol hydrobromide extend beyond pharmaceuticals. It is also utilized in material science, where its aromatic structure contributes to the development of advanced polymers and coatings. These materials often require specific chemical properties that can be tailored by incorporating functional groups like those present in this compound.

Regulatory considerations play a crucial role in the handling and commercialization of 4-Aminobenzene-1,2-diol hydrobromide. While it is not classified as a hazardous material under current regulations, proper safety protocols must be followed during synthesis and handling to ensure worker protection and environmental safety. Manufacturers must adhere to Good Manufacturing Practices (GMP) to maintain product quality and consistency.

The future prospects for 4-Aminobenzene-1,2-diol hydrobromide are promising, with ongoing research uncovering new applications and refining synthetic methodologies. Collaborative efforts between academia and industry will be essential in translating laboratory findings into clinical reality. As our understanding of biological systems grows, so too will the demand for innovative chemical tools like this compound.

In conclusion,4-Aminobenzene-1,2-diol hydrobromide (CAS No. 158627-59-9) is a multifaceted compound with significant potential in pharmaceuticals, materials science, and biochemical research. Its unique structural features make it a valuable intermediate for synthesizing bioactive molecules, while its functional groups offer opportunities for diverse applications. Continued exploration into its properties and applications will undoubtedly yield further advancements in science and medicine.

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• 91696-55-8(1,4-benzenediol, reaction products with aniline, branched octyl derivs.)
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