Cas no 158469-71-7 (tert-Butyl 4-(3-hydroxyprop-1-en-2-yl)piperidine-1-carboxylate)

Technical Introduction: tert-Butyl 4-(3-hydroxyprop-1-en-2-yl)piperidine-1-carboxylate is a versatile intermediate in organic synthesis, particularly valuable for its functionalized piperidine scaffold and reactive allylic alcohol moiety. The tert-butyloxycarbonyl (Boc) protecting group enhances stability during handling and storage while allowing selective deprotection under mild acidic conditions. The compound’s structural features, including the conjugated alkene and hydroxyl group, facilitate further derivatization, making it useful in pharmaceutical and agrochemical research. Its well-defined reactivity profile supports applications in cross-coupling reactions, nucleophilic additions, and cyclizations. The product is typically characterized by high purity and consistent performance, ensuring reliability in complex synthetic pathways. Proper storage under inert conditions is recommended to maintain integrity.
tert-Butyl 4-(3-hydroxyprop-1-en-2-yl)piperidine-1-carboxylate structure
158469-71-7 structure
Product Name:tert-Butyl 4-(3-hydroxyprop-1-en-2-yl)piperidine-1-carboxylate
CAS No:158469-71-7
MF:C13H23NO3
MW:241.326624155045
CID:1090279
PubChem ID:10999165
Update Time:2025-11-02

tert-Butyl 4-(3-hydroxyprop-1-en-2-yl)piperidine-1-carboxylate Chemical and Physical Properties

Names and Identifiers

    • tert-Butyl 4-(3-hydroxyprop-1-en-2-yl)piperidine-1-carboxylate
    • MFCD24473147
    • DTXSID10451347
    • 158469-71-7
    • Tert-butyl4-(3-hydroxyprop-1-en-2-yl)piperidine-1-carboxylate
    • DB-189296
    • SY263355
    • Inchi: 1S/C13H23NO3/c1-10(9-15)11-5-7-14(8-6-11)12(16)17-13(2,3)4/h11,15H,1,5-9H2,2-4H3
    • InChI Key: WBELQYAEKAZQID-UHFFFAOYSA-N
    • SMILES: O(C(C)(C)C)C(N1CCC(C(=C)CO)CC1)=O

Computed Properties

  • Exact Mass: 241.16779360g/mol
  • Monoisotopic Mass: 241.16779360g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 17
  • Rotatable Bond Count: 5
  • Complexity: 286
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 1.9
  • Topological Polar Surface Area: 49.8?2

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tert-Butyl 4-(3-hydroxyprop-1-en-2-yl)piperidine-1-carboxylate Related Literature

Additional information on tert-Butyl 4-(3-hydroxyprop-1-en-2-yl)piperidine-1-carboxylate

Comprehensive Guide to tert-Butyl 4-(3-hydroxyprop-1-en-2-yl)piperidine-1-carboxylate (CAS No. 158469-71-7)

tert-Butyl 4-(3-hydroxyprop-1-en-2-yl)piperidine-1-carboxylate (CAS No. 158469-71-7) is a specialized organic compound that has garnered significant attention in pharmaceutical and chemical research. This compound, often referred to as a piperidine derivative, is widely utilized in the synthesis of bioactive molecules due to its unique structural properties. Researchers and industry professionals are increasingly interested in this compound for its potential applications in drug discovery and material science.

The molecular structure of tert-Butyl 4-(3-hydroxyprop-1-en-2-yl)piperidine-1-carboxylate features a piperidine ring substituted with a tert-butyloxycarbonyl (Boc) protecting group and a hydroxypropene side chain. This combination of functional groups makes it a versatile intermediate in organic synthesis. The Boc group is particularly valuable in peptide synthesis and medicinal chemistry, as it protects amines during multi-step reactions. Meanwhile, the hydroxypropene moiety offers opportunities for further functionalization, enabling the creation of complex molecular architectures.

In recent years, the demand for piperidine-based compounds like tert-Butyl 4-(3-hydroxyprop-1-en-2-yl)piperidine-1-carboxylate has surged, driven by their role in developing new therapeutics. For instance, piperidine derivatives are frequently explored as building blocks for CNS-targeting drugs, anticancer agents, and anti-inflammatory compounds. This aligns with current trends in pharmaceutical research, where there is a growing emphasis on discovering novel small-molecule drugs with improved efficacy and safety profiles.

One of the key advantages of tert-Butyl 4-(3-hydroxyprop-1-en-2-yl)piperidine-1-carboxylate is its compatibility with modern synthetic techniques such as click chemistry and cross-coupling reactions. These methods are widely used in drug development and materials science, making this compound a valuable tool for chemists. Additionally, its stability under various reaction conditions enhances its utility in multi-step synthetic pathways.

The compound's relevance extends beyond pharmaceuticals. In material science, tert-Butyl 4-(3-hydroxyprop-1-en-2-yl)piperidine-1-carboxylate can serve as a precursor for functionalized polymers and advanced coatings. Researchers are investigating its potential in creating smart materials with applications in biomedical devices and sustainable packaging. This interdisciplinary appeal makes it a subject of interest in both academic and industrial settings.

From a commercial perspective, tert-Butyl 4-(3-hydroxyprop-1-en-2-yl)piperidine-1-carboxylate is available through specialized chemical suppliers, often in high purity grades suitable for research and development. Its CAS No. 158469-71-7 ensures precise identification in global chemical databases, facilitating procurement and regulatory compliance. As the demand for custom synthesis intermediates grows, this compound is poised to play a critical role in innovation across multiple sectors.

In summary, tert-Butyl 4-(3-hydroxyprop-1-en-2-yl)piperidine-1-carboxylate (CAS No. 158469-71-7) is a multifaceted compound with significant potential in pharmaceuticals, materials science, and beyond. Its unique structural features and compatibility with modern synthetic methods make it a valuable asset for researchers and industry professionals alike. As scientific advancements continue, this compound is likely to remain at the forefront of innovation in chemical synthesis and application development.

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