Cas no 1576216-95-9 (1-[(1,3,5-Trimethyl-1H-pyrazol-4-yl)sulfonyl]piperazine hydrochloride)
1-[(1,3,5-Trimethyl-1H-pyrazol-4-yl)sulfonyl]piperazine hydrochloride is a specialized sulfonamide derivative featuring a piperazine core functionalized with a trimethylpyrazole sulfonyl group. This compound exhibits notable reactivity as a versatile intermediate in organic synthesis, particularly in the development of pharmacologically active molecules. The hydrochloride salt enhances its solubility and stability, facilitating handling in synthetic applications. The trimethylpyrazole moiety contributes to steric and electronic modulation, making it valuable for structure-activity relationship (SAR) studies in medicinal chemistry. Its sulfonyl group enables selective nucleophilic substitutions, while the piperazine ring offers a flexible scaffold for further derivatization. This compound is particularly useful in the design of enzyme inhibitors and receptor ligands due to its balanced lipophilicity and hydrogen-bonding capacity.
![1-[(1,3,5-Trimethyl-1H-pyrazol-4-yl)sulfonyl]piperazine hydrochloride structure](https://ossimg.kuujia.com/scimg/1576500/1576216-95-9x500.png)
1576216-95-9 structure
Product Name:1-[(1,3,5-Trimethyl-1H-pyrazol-4-yl)sulfonyl]piperazine hydrochloride
CAS No:1576216-95-9
MF:C10H19ClN4O2S
MW:294.801459550858
CID:5042866
Update Time:2025-07-02
1-[(1,3,5-Trimethyl-1H-pyrazol-4-yl)sulfonyl]piperazine hydrochloride Chemical and Physical Properties
Names and Identifiers
-
- 1-[(1,3,5-trimethyl-1H-pyrazol-4-yl)sulfonyl]piperazine hydrochloride
- 1-((1,3,5-Trimethyl-1H-pyrazol-4-yl)sulfonyl)piperazine hydrochloride
- 1-(1,3,5-trimethylpyrazol-4-yl)sulfonylpiperazine;hydrochloride
- 1-[(1,3,5-Trimethyl-1H-pyrazol-4-yl)sulfonyl]piperazine hydrochloride
-
- Inchi： 1S/C10H18N4O2S.ClH/c1-8-10(9(2)13(3)12-8)17(15,16)14-6-4-11-5-7-14;/h11H,4-7H2,1-3H3;1H
- InChI Key： KPUSWQMXKCFFFQ-UHFFFAOYSA-N
- SMILES： Cl.S(C1C(C)=NN(C)C=1C)(N1CCNCC1)(=O)=O
Computed Properties
- Hydrogen Bond Donor Count: 2
- Hydrogen Bond Acceptor Count: 5
- Heavy Atom Count: 18
- Rotatable Bond Count: 2
- Complexity: 361
- Topological Polar Surface Area: 75.6
1-[(1,3,5-Trimethyl-1H-pyrazol-4-yl)sulfonyl]piperazine hydrochloride Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| TRC | T141696-100mg |
1-[(1,3,5-trimethyl-1h-pyrazol-4-yl)sulfonyl]piperazine hydrochloride |
1576216-95-9 | 100mg |
$ 95.00 | 2022-06-02 | ||
| TRC | T141696-500mg |
1-[(1,3,5-trimethyl-1h-pyrazol-4-yl)sulfonyl]piperazine hydrochloride |
1576216-95-9 | 500mg |
$ 365.00 | 2022-06-02 | ||
| TRC | T141696-1g |
1-[(1,3,5-trimethyl-1h-pyrazol-4-yl)sulfonyl]piperazine hydrochloride |
1576216-95-9 | 1g |
$ 570.00 | 2022-06-02 | ||
| Life Chemicals | F2158-1709-0.25g |
1-[(1,3,5-trimethyl-1H-pyrazol-4-yl)sulfonyl]piperazine hydrochloride |
1576216-95-9 | 95%+ | 0.25g |
$523.0 | 2023-09-06 | |
| Life Chemicals | F2158-1709-0.5g |
1-[(1,3,5-trimethyl-1H-pyrazol-4-yl)sulfonyl]piperazine hydrochloride |
1576216-95-9 | 95%+ | 0.5g |
$551.0 | 2023-09-06 | |
| Life Chemicals | F2158-1709-1g |
1-[(1,3,5-trimethyl-1H-pyrazol-4-yl)sulfonyl]piperazine hydrochloride |
1576216-95-9 | 95%+ | 1g |
$580.0 | 2023-09-06 | |
| Life Chemicals | F2158-1709-2.5g |
1-[(1,3,5-trimethyl-1H-pyrazol-4-yl)sulfonyl]piperazine hydrochloride |
1576216-95-9 | 95%+ | 2.5g |
$1267.0 | 2023-09-06 | |
| Life Chemicals | F2158-1709-5g |
1-[(1,3,5-trimethyl-1H-pyrazol-4-yl)sulfonyl]piperazine hydrochloride |
1576216-95-9 | 95%+ | 5g |
$1909.0 | 2023-09-06 | |
| Life Chemicals | F2158-1709-10g |
1-[(1,3,5-trimethyl-1H-pyrazol-4-yl)sulfonyl]piperazine hydrochloride |
1576216-95-9 | 95%+ | 10g |
$2675.0 | 2023-09-06 |
1-[(1,3,5-Trimethyl-1H-pyrazol-4-yl)sulfonyl]piperazine hydrochloride Related Literature
-
Yi Cao,Yujiao Xiahou,Lixiang Xing,Xiang Zhang,Hong Li,ChenShou Wu,Haibing Xia Nanoscale, 2020,12, 20456-20466
-
Manickam Bakthadoss,Tadiparthi Thirupathi Reddy,Vishal Agarwal,Duddu S. Sharada Chem. Commun., 2022,58, 1406-1409
-
Jason Wan Lab Chip, 2020,20, 4528-4538
-
Chung-Sung Yang,Mong-Shian Shih,Fang-Yi Chang New J. Chem., 2006,30, 729-735
1576216-95-9 (1-[(1,3,5-Trimethyl-1H-pyrazol-4-yl)sulfonyl]piperazine hydrochloride) Related Products
- 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
- 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
- 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
- 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
- 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
- 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
- 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
- 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
- 1449132-38-0(3-Fluoro-5-(2-fluoro-5-methylbenzylcarbamoyl)benzeneboronic acid)
- 2034271-14-0(2-(1H-indol-3-yl)-N-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}acetamide)
Recommended suppliers
Amadis Chemical Company Limited
Gold Member
Audited Supplier
CN Supplier
Reagent
Hangzhou Cedareal Technology Co., Ltd.
Gold Member
Audited Supplier
CN Supplier
Bulk
Shenzhen Jianxing Pharmaceutical Technology Co., Ltd.
Gold Member
Audited Supplier
CN Supplier
Reagent
Suzhou Genelee Bio-Technology Co., Ltd.
Gold Member
Audited Supplier
CN Supplier
Bulk
Jinta Yudi Pharmaceutical Technology Co., Ltd.
Gold Member
Audited Supplier
CN Supplier
Bulk
