• 1. Evolution in surface coverage of CH3NH3PbI3?XClXvia heat assisted solvent vapour treatment and their effects on photovoltaic performance of devices
  Dhirendra K. Chaudhary,Pramendra Kumar,Lokendra Kumar RSC Adv., 2016,6, 94731-94738
• 2. Establishing plasmon contribution to chemical reactions: alkoxyamines as a thermal probe?
  Olga Guselnikova,Gérard Audran,Jean-Patrick Joly,Andrii Trelin,Evgeny V. Tretyakov,Vaclav Svorcik,Oleksiy Lyutakov,Sylvain R. A. Marque Chem. Sci., 2021,12, 4154-4161
• 3. Emergence of microfluidic wearable technologies
  Joo Chuan Yeo,Kenry Lab Chip, 2016,16, 4082-4090
• 4. Dissociation of aryl sulfonyl phthalimide radical anions: relevance to the biological activity of arylsulfonyl amides?
  Abdelaziz Houmam,Emad M. Hamed Chem. Commun., 2012,48, 11328-11330
• 5. Fate of Sb(v) and Sb(iii) species along a gradient of pH and oxygen concentration in the Carnoulès mine waters (Southern France)
  Eléonore Resongles,Corinne Casiot,Fran?oise Elbaz-Poulichet,Rémi Freydier,Odile Bruneel,Christine Piot,Sophie Delpoux,Aurélie Volant,Angélique Desoeuvre Environ. Sci.: Processes Impacts, 2013,15, 1536-1544

• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Bromobenzenes
• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Halobenzenes Bromobenzenes

Introduction to (2-Bromo-5-methylphenyl)methanesulfonamide (CAS No. 1565690-82-5)

Compound with the CAS number 1565690-82-5 and the product name (2-Bromo-5-methylphenyl)methanesulfonamide represents a significant area of interest in the field of chemical and pharmaceutical research. This compound, characterized by its unique molecular structure, has garnered attention due to its potential applications in various scientific domains. The presence of both bromine and methyl substituents on the phenyl ring, coupled with the methanesulfonamide functional group, imparts distinct chemical properties that make it a valuable candidate for further exploration.

The molecular structure of (2-Bromo-5-methylphenyl)methanesulfonamide consists of a phenyl ring substituted at the 2-position with a bromine atom and at the 5-position with a methyl group. The methanesulfonamide moiety is attached to the ring, contributing to its overall reactivity and utility. This specific arrangement of atoms endows the compound with a set of characteristics that are both challenging and intriguing for researchers.

In recent years, there has been a growing interest in exploring the pharmacological properties of aromatic sulfonamides. The sulfonamide group is well-known for its role in medicinal chemistry, particularly due to its presence in numerous drugs that have demonstrated efficacy in treating various diseases. The introduction of halogen substituents, such as bromine, can further modulate the pharmacokinetic and pharmacodynamic properties of these compounds, making them more suitable for specific therapeutic applications.

One of the most compelling aspects of (2-Bromo-5-methylphenyl)methanesulfonamide is its potential as a building block for more complex molecules. Researchers have been leveraging this compound to synthesize novel derivatives that exhibit enhanced biological activity. For instance, studies have shown that modifications at the bromine and methyl positions can significantly alter the binding affinity and selectivity of sulfonamides towards target enzymes and receptors.

The synthesis of (2-Bromo-5-methylphenyl)methanesulfonamide involves multi-step organic reactions that require careful optimization to ensure high yield and purity. Advanced synthetic methodologies, including cross-coupling reactions and nucleophilic substitutions, have been employed to construct the desired molecular framework. These synthetic strategies not only highlight the compound's complexity but also showcase the advancements in synthetic organic chemistry that enable such intricate constructions.

Recent research has begun to uncover the biological significance of this compound. Studies have indicated that derivatives of sulfonamides can exhibit antimicrobial, anti-inflammatory, and even anticancer properties. The specific arrangement of substituents in (2-Bromo-5-methylphenyl)methanesulfonamide may contribute to its ability to interact with biological targets in unique ways, potentially leading to new therapeutic interventions.

The chemical reactivity of (2-Bromo-5-methylphenyl)methanesulfonamide also makes it a valuable tool for mechanistic studies. Researchers are investigating how this compound behaves under various conditions, which could provide insights into broader chemical principles. Understanding these reaction mechanisms is crucial for developing more efficient synthetic routes and for predicting the behavior of related compounds.

In conclusion, (2-Bromo-5-methylphenyl)methanesulfonamide (CAS No. 1565690-82-5) represents a fascinating subject of study in chemical biology and pharmaceutical chemistry. Its unique structure and reactivity offer numerous opportunities for further research, potentially leading to new applications in medicine and materials science. As our understanding of this compound continues to grow, so too will its significance in advancing scientific knowledge.

• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
• 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
• 1449132-38-0(3-Fluoro-5-(2-fluoro-5-methylbenzylcarbamoyl)benzeneboronic acid)
• 2034271-14-0(2-(1H-indol-3-yl)-N-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}acetamide)