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N,3-dimethylpyridin-2-amine (CAS No. 156267-13-9): Properties, Applications, and Market Insights

N,3-dimethylpyridin-2-amine (CAS No. 156267-13-9) is a specialized organic compound belonging to the pyridine derivative family. This compound, also known as 2-amino-N,3-dimethylpyridine, has garnered significant attention in pharmaceutical and agrochemical research due to its unique structural properties. The molecular formula C7H10N2 indicates its potential as a versatile building block in synthetic chemistry.

The growing interest in N,3-dimethylpyridin-2-amine derivatives stems from their applications in drug discovery, particularly in developing kinase inhibitors and other therapeutic agents. Recent studies highlight its role in creating novel heterocyclic compounds with improved bioavailability, addressing one of the pharmaceutical industry's current challenges - enhancing drug delivery systems.

From a chemical perspective, N,3-dimethylpyridin-2-amine synthesis typically involves methylation reactions of pyridine precursors. The compound's physical and chemical properties make it valuable for various applications: molecular weight 122.17 g/mol, melting point range between 45-50°C, and good solubility in common organic solvents. These characteristics contribute to its handling and processing advantages in laboratory settings.

In material science, researchers are exploring N,3-dimethylpyridin-2-amine applications in creating advanced functional materials. Its ability to coordinate with metal ions makes it promising for developing catalysts and sensors. The compound's electronic properties are particularly relevant to current research in organic electronics and energy storage solutions.

The global market for pyridine derivatives like N,3-dimethylpyridin-2-amine is experiencing steady growth, driven by pharmaceutical demand and specialty chemical applications. Industry analysts project a compound annual growth rate (CAGR) of 5-7% through 2028, with Asia-Pacific regions showing particularly strong demand for fine chemical intermediates in drug manufacturing.

Quality control standards for CAS 156267-13-9 typically require HPLC purity ≥98%, with strict limits on residual solvents and heavy metals. Reputable suppliers provide comprehensive analytical data including NMR, MS, and chromatographic profiles to ensure batch-to-batch consistency for research and production purposes.

Environmental and safety considerations for N,3-dimethylpyridin-2-amine handling follow standard laboratory protocols. While not classified as highly hazardous, proper ventilation and personal protective equipment are recommended during manipulation. The compound's stability profile suggests good shelf life when stored under appropriate conditions (typically 2-8°C in airtight containers).

Recent patent literature reveals innovative applications of N,3-dimethylpyridin-2-amine scaffolds in medicinal chemistry. Several 2023-2024 filings describe its incorporation into novel compounds targeting neurological disorders and metabolic diseases, reflecting the pharmaceutical industry's focus on these therapeutic areas.

Academic interest in 156267-13-9 chemical properties continues to grow, with research groups investigating its potential in asymmetric synthesis and chiral auxiliary applications. The compound's structural features make it attractive for developing stereoselective catalysts, addressing the increasing demand for enantiomerically pure pharmaceuticals.

Supply chain dynamics for N,3-dimethylpyridin-2-amine suppliers indicate stable availability from major chemical manufacturers, with lead times typically ranging from 2-4 weeks for custom quantities. Pricing trends show moderate fluctuations tied to precursor material costs and regional production capacities.

Future research directions for pyridine amine derivatives like N,3-dimethylpyridin-2-amine may explore their use in sustainable chemistry applications. The compound's potential in green synthesis methods and biodegradable material development aligns with current industry priorities toward environmentally friendly processes.

Analytical characterization techniques for CAS No. 156267-13-9 typically combine spectroscopic methods (FTIR, NMR) with chromatographic analysis. Advanced mass spectrometry approaches are increasingly employed to study its fragmentation patterns and reaction pathways, supporting mechanistic studies in synthetic applications.

Regulatory status of N,3-dimethylpyridin-2-amine varies by region, but it generally falls under standard chemical substance regulations rather than specialized controls. Compliance with REACH, TSCA, and other regional chemical inventories is maintained by major producers and distributors.

The compound's role in medicinal chemistry research continues to expand, with recent studies highlighting its utility in fragment-based drug discovery. Its balanced lipophilicity and hydrogen bonding capacity make it particularly valuable for optimizing drug-like properties in lead compounds.

Technical literature on N,3-dimethylpyridin-2-amine synthesis methods describes various optimization approaches, including microwave-assisted reactions and continuous flow chemistry techniques. These modern synthetic strategies improve yields and reduce environmental impact compared to traditional batch processes.

Emerging applications in agricultural chemistry suggest potential uses for N,3-dimethylpyridin-2-amine derivatives in developing next-generation crop protection agents. The compound's structural features may contribute to novel modes of action against resistant pest strains.

For researchers considering 156267-13-9 purchase, factors to evaluate include supplier reliability, analytical documentation quality, and packaging options suitable for specific research needs. Many providers now offer customized solutions ranging from milligram-scale samples to kilogram quantities for development projects.

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• 4931-01-5(2-Hydrazinyl-5-Methylpyridine)
• 4930-99-8(2-Hydrazinyl-3-methylpyridine)
• 1603-40-3(3-methylpyridin-2-amine)
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