• 1. An algal process treatment combined with the Fenton reaction for high concentrations of amoxicillin and cefradine
  Haitao Li,Yu Pan,Zhizhi Wang,Shan Chen,Ruixin Guo,Jianqiu Chen RSC Adv., 2015,5, 100775-100782
• 2. An integrated process of CO2 capture and in situ hydrogenation to formate using a tunable ethoxyl-functionalized amidine and Rh/bisphosphine system?
  Yu-Nong Li,Liang-Nian He,Xian-Dong Lang,Xiao-Fang Liu,Shuai Zhang RSC Adv., 2014,4, 49995-50002
• 3. An insight into the hybridization mechanism of hairpin DNA physically immobilized on chemically modified graphenes
  Adeline Huiling Loo,Alessandra Bonanni,Martin Pumera Analyst, 2013,138, 467-471
• 4. An artificial blood vessel implanted three-dimensional microsystem for modeling transvascular migration of tumor cells?
  Xue-Ying Wang,Ying Pei,Min Xie,Zi-He Jin,Ya-Shi Xiao,Yang Wang,Li-Na Zhang,Yan Li,Wei-Hua Huang Lab Chip, 2015,15, 1178-1187
• 5. Acetylcholinesterase amperometric detection system based on a cobalt(II) tetraphenylporphyrin-modified electrode
  Analyst, 1996,121, 1123-1126

• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Benzoic acids
• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Benzoic acids and derivatives Benzoic acids

4-Carbamimidoylbenzoic Acid (CAS No. 15535-95-2): Properties, Applications, and Market Insights

4-Carbamimidoylbenzoic acid (CAS No. 15535-95-2) is a specialized organic compound with significant potential in pharmaceutical and biochemical research. This white to off-white crystalline powder belongs to the class of benzoic acid derivatives, featuring a carbamimidoyl functional group at the para position. Its molecular formula is C₈H₈N₂O₂, with a molecular weight of 164.16 g/mol. The compound's unique structure makes it valuable for various synthetic applications, particularly in drug discovery and development.

The growing interest in 4-Carbamimidoylbenzoic acid derivatives stems from their role as intermediates in medicinal chemistry. Researchers frequently search for "4-Carbamimidoylbenzoic acid synthesis" and "benzoic acid derivatives in drug design," reflecting the compound's relevance in current pharmaceutical trends. Its structural features allow for diverse modifications, making it a versatile building block for creating novel therapeutic agents targeting metabolic disorders and inflammatory conditions.

From a chemical perspective, 4-Carbamimidoylbenzoic acid demonstrates interesting properties. The compound typically melts between 220-225°C and shows limited solubility in water but better solubility in polar organic solvents like dimethyl sulfoxide (DMSO) or dimethylformamide (DMF). These characteristics are crucial for researchers investigating "solubility of benzoic acid derivatives" or "handling carbamimidoyl compounds." The presence of both carboxylic acid and carbamimidoyl groups provides two distinct reactive sites for chemical transformations.

In pharmaceutical applications, 4-Carbamimidoylbenzoic acid serves as a key intermediate for developing enzyme inhibitors. Recent publications highlight its use in creating compounds that modulate arginase activity, addressing questions like "how does 4-Carbamimidoylbenzoic acid affect enzyme function?" This connection to enzyme inhibition research aligns with current interests in targeted therapies for cardiovascular and immune-related conditions.

The analytical characterization of 4-Carbamimidoylbenzoic acid typically involves techniques such as HPLC, NMR spectroscopy, and mass spectrometry. Quality control specifications for research-grade material usually require ≥95% purity, with common impurities being starting materials from its synthesis. These analytical parameters respond to frequent searches about "purity standards for research chemicals" and "analytical methods for benzoic acid derivatives."

Market trends indicate growing demand for 4-Carbamimidoylbenzoic acid in the pharmaceutical and biotechnology sectors. Suppliers often receive inquiries about "bulk 4-Carbamimidoylbenzoic acid suppliers" and "custom synthesis of benzoic acid derivatives." The compound's price varies based on purity grade and quantity, with research-scale quantities typically ranging from $50-$200 per gram. Current Good Manufacturing Practice (cGMP) compliant material commands premium pricing for clinical research applications.

Storage and handling recommendations for 4-Carbamimidoylbenzoic acid include keeping the compound in a cool, dry place away from direct sunlight. While not classified as hazardous under standard conditions, proper laboratory practices should be followed, including the use of personal protective equipment. These precautions address common safety-related searches such as "storage conditions for carbamimidoyl compounds" and "benzoic acid derivative safety data."

Recent scientific literature reveals innovative applications of 4-Carbamimidoylbenzoic acid in materials science. Researchers are exploring its incorporation into metal-organic frameworks (MOFs) and coordination polymers, responding to growing interest in "organic linkers for MOF synthesis." The compound's rigid aromatic core and multiple coordination sites make it attractive for designing porous materials with potential applications in gas storage and separation technologies.

Quality assurance for 4-Carbamimidoylbenzoic acid involves rigorous testing protocols. Reputable suppliers provide certificates of analysis including information on identity (by FTIR or NMR), purity (by HPLC), and residual solvent content. These quality measures answer frequent customer questions about "how to verify benzoic acid derivative purity" and "analytical certificates for research chemicals." Independent verification through third-party testing is recommended for critical applications.

The future outlook for 4-Carbamimidoylbenzoic acid appears promising, particularly in personalized medicine approaches. Its structural versatility positions it well for emerging trends in "fragment-based drug discovery" and "small molecule probes for biological systems." As research into targeted therapies expands, demand for high-quality 4-Carbamimidoylbenzoic acid and related derivatives is expected to grow steadily in both academic and industrial research settings.

• 42823-63-2(3-(aminoiminomethyl)-benzoic acid hcl)
• 71492-07-4(Benzenecarboximidamide, monoacetate)
• 50466-15-4(4-Methoxycarbonylbenzamidine Diacetic Acid Salt)
• 42823-72-3(4-Carbamimidoylbenzoic acid hydrochloride)
• 14209-67-7(Benzoic acid,4-(aminoiminomethyl)-, phenylmethyl ester)
• 199447-10-4(3-(Hydroxyamino)iminomethyl-benzoic acid)
• 18219-39-1(3-Methoxycarbonyl Benzamidine Hydrochloride)
• 52820-49-2(3-carbamimidoyl-benzoic acid)
• 5418-97-3((Z)-[4-(ethoxycarbonyl)phenyl](imino)methanaminium chloride)
• 42823-73-4(Methyl 4-carbamimidoylbenzoate hydrochloride)