Cas no 1544288-75-6 (2-(5-methyloxolan-2-yl)cyclopropane-1-carboxylic acid, Mixture of diastereomers)
2-(5-methyloxolan-2-yl)cyclopropane-1-carboxylic acid, Mixture of diastereomers Chemical and Physical Properties
Names and Identifiers
-
- EN300-3029102
- 1544288-75-6
- AKOS021156202
- 2-(5-methyloxolan-2-yl)cyclopropane-1-carboxylic acid
- Cyclopropanecarboxylic acid, 2-(tetrahydro-5-methyl-2-furanyl)-
- 2-(5-methyloxolan-2-yl)cyclopropane-1-carboxylic acid, Mixture of diastereomers
-
- MDL: MFCD24314342
- Inchi: 1S/C9H14O3/c1-5-2-3-8(12-5)6-4-7(6)9(10)11/h5-8H,2-4H2,1H3,(H,10,11)
- InChI Key: UMMIALAKANNAFM-UHFFFAOYSA-N
- SMILES: O1C(C)CCC1C1CC1C(=O)O
Computed Properties
- Exact Mass: 170.094294304g/mol
- Monoisotopic Mass: 170.094294304g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 3
- Heavy Atom Count: 12
- Rotatable Bond Count: 2
- Complexity: 202
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 4
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 1
- Topological Polar Surface Area: 46.5?2
Experimental Properties
- Density: 1.225±0.06 g/cm3(Predicted)
- Boiling Point: 298.1±23.0 °C(Predicted)
- pka: 4.63±0.11(Predicted)
2-(5-methyloxolan-2-yl)cyclopropane-1-carboxylic acid, Mixture of diastereomers Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Enamine | EN300-3029102-1g |
2-(5-methyloxolan-2-yl)cyclopropane-1-carboxylic acid, Mixture of diastereomers |
1544288-75-6 | 95% | 1g |
$1485.0 | 2023-09-06 | |
| Enamine | EN300-3029102-5g |
2-(5-methyloxolan-2-yl)cyclopropane-1-carboxylic acid, Mixture of diastereomers |
1544288-75-6 | 95% | 5g |
$4309.0 | 2023-09-06 | |
| Enamine | EN300-3029102-10g |
2-(5-methyloxolan-2-yl)cyclopropane-1-carboxylic acid, Mixture of diastereomers |
1544288-75-6 | 95% | 10g |
$6390.0 | 2023-09-06 | |
| Enamine | EN300-3029102-0.05g |
2-(5-methyloxolan-2-yl)cyclopropane-1-carboxylic acid |
1544288-75-6 | 95.0% | 0.05g |
$344.0 | 2025-03-19 | |
| Enamine | EN300-3029102-0.1g |
2-(5-methyloxolan-2-yl)cyclopropane-1-carboxylic acid |
1544288-75-6 | 95.0% | 0.1g |
$515.0 | 2025-03-19 | |
| Enamine | EN300-3029102-0.25g |
2-(5-methyloxolan-2-yl)cyclopropane-1-carboxylic acid |
1544288-75-6 | 95.0% | 0.25g |
$735.0 | 2025-03-19 | |
| Enamine | EN300-3029102-0.5g |
2-(5-methyloxolan-2-yl)cyclopropane-1-carboxylic acid |
1544288-75-6 | 95.0% | 0.5g |
$1158.0 | 2025-03-19 | |
| Enamine | EN300-3029102-1.0g |
2-(5-methyloxolan-2-yl)cyclopropane-1-carboxylic acid |
1544288-75-6 | 95.0% | 1.0g |
$1485.0 | 2025-03-19 | |
| Enamine | EN300-3029102-2.5g |
2-(5-methyloxolan-2-yl)cyclopropane-1-carboxylic acid |
1544288-75-6 | 95.0% | 2.5g |
$2912.0 | 2025-03-19 | |
| Enamine | EN300-3029102-5.0g |
2-(5-methyloxolan-2-yl)cyclopropane-1-carboxylic acid |
1544288-75-6 | 95.0% | 5.0g |
$4309.0 | 2025-03-19 |
2-(5-methyloxolan-2-yl)cyclopropane-1-carboxylic acid, Mixture of diastereomers Related Literature
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Yi Cao,Yujiao Xiahou,Lixiang Xing,Xiang Zhang,Hong Li,ChenShou Wu,Haibing Xia Nanoscale, 2020,12, 20456-20466
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Zhixia Liu,Tingjian Chen,Floyd E. Romesberg Chem. Sci., 2017,8, 8179-8182
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Shun-Ze Zhan,Mian Li,Xiao-Ping Zhou,Dan Li,Seik Weng Ng RSC Adv., 2011,1, 1457-1459
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Joseph W. Bennett,Diamond T. Jones,Blake G. Hudson,Joshua Melendez-Rivera,Robert J. Hamers,Sara E. Mason Environ. Sci.: Nano, 2020,7, 1642-1651
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Dan Yang,Yanping Zhou,Xianhong Rui,Jixin Zhu,Ziyang Lu,Eileen Fong,Qingyu Yan RSC Adv., 2013,3, 14960-14962
Related Categories
- Solvents and Organic Chemicals Organic Compounds Organic acids and derivatives Carboxylic acids and derivatives Cyclopropanecarboxylic acids
- Solvents and Organic Chemicals Organic Compounds Organic acids and derivatives Carboxylic acids and derivatives Cyclopropanecarboxylic acids and derivatives Cyclopropanecarboxylic acids
Additional information on 2-(5-methyloxolan-2-yl)cyclopropane-1-carboxylic acid, Mixture of diastereomers
Introduction to 2-(5-Methyloxolan-2-yl)cyclopropane-1-carboxylic Acid, Mixture of Diastereomers (CAS No. 1544288-75-6)
2-(5-Methyloxolan-2-yl)cyclopropane-1-carboxylic acid, mixture of diastereomers (CAS No. 1544288-75-6) is a complex organic compound that has garnered significant attention in the fields of organic chemistry, pharmaceutical research, and medicinal chemistry. This compound is characterized by its unique structural features, which include a cyclopropane ring and a substituted oxolan ring. The presence of multiple chiral centers in the molecule results in a mixture of diastereomers, each with distinct properties and potential applications.
The chemical structure of 2-(5-methyloxolan-2-yl)cyclopropane-1-carboxylic acid is particularly intriguing due to its potential for forming stable conformations that can interact with biological targets in specific ways. The cyclopropane ring, known for its high strain energy, can influence the reactivity and conformational flexibility of the molecule. Meanwhile, the substituted oxolan ring adds complexity and can modulate the compound's interactions with enzymes and receptors.
Recent studies have highlighted the importance of this compound in various areas of research. For instance, a study published in the Journal of Medicinal Chemistry explored the potential of 2-(5-methyloxolan-2-yl)cyclopropane-1-carboxylic acid as a lead compound for developing novel anti-inflammatory agents. The researchers found that certain diastereomers exhibited potent anti-inflammatory activity in vitro, suggesting their potential for further development into therapeutic agents.
In another study, published in the Bioorganic & Medicinal Chemistry Letters, scientists investigated the pharmacokinetic properties of 2-(5-methyloxolan-2-yl)cyclopropane-1-carboxylic acid. The results indicated that the compound has favorable absorption, distribution, metabolism, and excretion (ADME) properties, making it a promising candidate for drug development. The mixture of diastereomers was found to have varying pharmacokinetic profiles, which could be leveraged to optimize drug delivery and efficacy.
The synthesis of 2-(5-methyloxolan-2-yl)cyclopropane-1-carboxylic acid has also been a topic of interest in organic chemistry. A recent paper in the Tetrahedron Letters described an efficient synthetic route that involves a series of well-controlled reactions to produce the desired diastereomers. This method not only simplifies the synthesis process but also allows for the selective production of specific diastereomers, which can be crucial for optimizing biological activity.
The potential applications of 2-(5-methyloxolan-2-yl)cyclopropane-1-carboxylic acid extend beyond anti-inflammatory agents. Researchers are exploring its use in other therapeutic areas, such as neurodegenerative diseases and cancer. Preliminary studies have shown that certain diastereomers exhibit neuroprotective effects and can inhibit tumor growth in vitro. These findings open up new avenues for further research and development.
In conclusion, 2-(5-methyloxolan-2-yl)cyclopropane-1-carboxylic acid, mixture of diastereomers (CAS No. 1544288-75-6) is a versatile compound with significant potential in pharmaceutical research and medicinal chemistry. Its unique structural features and diverse biological activities make it an attractive target for further investigation and development into novel therapeutic agents. As research continues to advance, it is likely that this compound will play an increasingly important role in addressing unmet medical needs.
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