• 1. Fe/Fe3C@C nanoparticles encapsulated in N-doped graphene–CNTs framework as an efficient bifunctional oxygen electrocatalyst for robust rechargeable Zn–air batteries?
  Zhiyan Chen,Nan Wu,Yaobing Wang,Bing Wang,Yingde Wang J. Mater. Chem. A, 2018,6, 516-526
• 2. Evidence for the intrinsic nature of band-gap states electrochemically observed on atomically flat TiO2(110) surfaces?
  Shintaro Takata,Yoshihiro Miura Phys. Chem. Chem. Phys., 2014,16, 24784-24789
• 3. Enantio- & chemo-selective preparation of enantiomerically enriched aliphatic nitro alcohols using Candida parapsilosis ATCC 7330
  Sowmyalakshmi Venkataraman RSC Adv., 2015,5, 73807-73813
• 4. Emergence of microfluidic wearable technologies
  Joo Chuan Yeo,Kenry Lab Chip, 2016,16, 4082-4090
• 5. Evidence of field induced slow magnetic relaxation in cis-[Co(hfac)2(H2O)2] exhibiting tri-axial anisotropy with a negative axial component?
  Denis V. Korchagin,Elena A. Yureva,Alexander V. Akimov,Eugenii Ya. Misochko,Gennady V. Shilov,Artem D. Talantsev,Roman B. Morgunov,Alexander A. Shakin,Sergey M. Aldoshin,Boris S. Tsukerblat Dalton Trans., 2017,46, 7540-7548

Methyl 2-(4-Methoxyphenyl)-1,3-Oxazole-4-Carboxylate: A Comprehensive Overview

Methyl 2-(4-methoxyphenyl)-1,3-oxazole-4-carboxylate, also known by its CAS number CAS No. 154405-98-8, is a compound of significant interest in the fields of organic chemistry and pharmaceutical research. This compound belongs to the class of oxazole derivatives, which have been extensively studied for their diverse applications in drug discovery and material science. The structure of this compound consists of a methyl ester group attached to a 1,3-oxazole ring, which is further substituted with a 4-methoxyphenyl group. This unique combination of functional groups imparts distinctive chemical and biological properties to the molecule.

The synthesis of methyl 2-(4-methoxyphenyl)-1,3-oxazole-4-carboxylate typically involves a multi-step process that includes nucleophilic substitution, condensation reactions, and esterification. Recent advancements in synthetic methodologies have enabled the efficient preparation of this compound with high purity and yield. Researchers have explored various catalysts and reaction conditions to optimize the synthesis process, making it more environmentally friendly and cost-effective.

One of the most notable applications of this compound lies in its potential as a building block for more complex molecules. The oxazole ring is known for its stability and reactivity under specific conditions, making it an ideal scaffold for drug design. For instance, studies have shown that derivatives of this compound exhibit promising anti-inflammatory and antioxidant activities. These findings suggest that methyl 2-(4-methoxyphenyl)-1,3-oxazole-4-carboxylate could serve as a lead compound for developing novel therapeutic agents targeting chronic inflammatory diseases.

In addition to its pharmacological applications, this compound has also been investigated for its role in materials science. The presence of the methoxyphenyl group introduces electronic and steric effects that can influence the optical and electronic properties of materials. Recent research has focused on incorporating this compound into polymer matrices to enhance their mechanical strength and thermal stability. Such applications highlight the versatility of methyl 2-(4-methoxyphenyl)-1,3-oxazole-4-carboxylate beyond traditional chemical synthesis.

The biological evaluation of this compound has revealed interesting insights into its pharmacokinetic profile. Studies conducted in vitro and in vivo have demonstrated moderate absorption and metabolism rates, suggesting that it could be suitable for oral administration in certain therapeutic contexts. Furthermore, preliminary toxicity studies indicate that this compound exhibits low cytotoxicity against normal human cells, which is a crucial factor for its potential use in drug development.

From an environmental perspective, the biodegradability and eco-toxicity of methyl 2-(4-methoxyphenyl)-1,3-oxazole-4-carboxylate have been assessed under controlled laboratory conditions. Results indicate that the compound undergoes slow degradation under aerobic conditions, raising concerns about its long-term impact on aquatic ecosystems. However, ongoing research aims to develop sustainable methods for its production and disposal to mitigate environmental risks.

In conclusion, methyl 2-(4-methoxyphenyl)-1,3-oxazole-4-carboxylate (CAS No. 154405-98-8) is a versatile compound with promising applications in various fields. Its unique chemical structure and favorable biological properties make it an attractive candidate for further research and development. As scientific advancements continue to unfold, this compound is expected to play an increasingly important role in both academic and industrial settings.

• 39819-39-1(ethyl 2-phenyl-1,3-oxazole-4-carboxylate)
• 59171-72-1(methyl 2-phenyl-1,3-oxazole-4-carboxylate)
• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
• 89640-58-4(2-Iodo-4-nitrophenylhydrazine)