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• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Azoles Phenyl-1,3-oxazoles
• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Azoles Oxazoles Phenyl-1,3-oxazoles

2-(2-Methylphenyl)-1,3-Oxazole-4-Carbaldehyde: A Comprehensive Overview

The compound 2-(2-methylphenyl)-1,3-oxazole-4-carbaldehyde (CAS No. 154136-88-6) is a fascinating molecule with a unique structure and diverse applications. This compound belongs to the class of aromatic aldehydes and features a heterocyclic oxazole ring fused with a benzene ring. The presence of the methyl group at the 2-position of the phenyl ring adds to its structural complexity and functional diversity. Recent studies have highlighted its potential in various fields, including materials science, pharmaceuticals, and organic synthesis.

Oxazole, a five-membered heterocyclic compound containing one oxygen and one nitrogen atom, is known for its stability and reactivity. In 2-(2-methylphenyl)-1,3-oxazole-4-carbaldehyde, the oxazole ring is substituted with an aldehyde group at the 4-position and a methyl-substituted phenyl group at the 2-position. This substitution pattern imparts unique electronic properties to the molecule, making it highly versatile in chemical reactions. The compound's ability to undergo various nucleophilic additions and condensations has made it a valuable building block in organic synthesis.

Recent research has focused on the synthesis and characterization of 2-(2-methylphenyl)-1,3-oxazole-4-carbaldehyde using advanced techniques such as microwave-assisted synthesis and catalytic methods. These studies have demonstrated that the compound can be efficiently synthesized in high yields under mild conditions. Its structural elucidation has been carried out using modern spectroscopic techniques like NMR and IR spectroscopy, confirming its molecular structure and purity.

The applications of 2-(2-methylphenyl)-1,3-oxazole-4-carbaldehyde are vast and continue to expand with ongoing research. In the field of materials science, this compound has been explored as a precursor for the synthesis of advanced materials such as conductive polymers and metal-organic frameworks (MOFs). Its ability to form stable coordination complexes with transition metals makes it a promising candidate for use in catalysis and sensor applications.

In pharmaceuticals, 2-(2-methylphenyl)-1,3-oxazole-4-carbaldehyde has shown potential as an anti-inflammatory agent due to its ability to inhibit cyclooxygenase enzymes. Recent studies have also investigated its anti-cancer properties, where it has demonstrated selective cytotoxicity against cancer cells without significantly affecting normal cells. These findings underscore its potential as a lead compound for drug development.

The compound's role in organic synthesis is another area of active research. Its aldehyde functionality allows for the formation of various derivatives through condensation reactions with ketones, alcohols, and amines. These derivatives have found applications in agrochemicals, dyes, and flavor compounds. Moreover, its methyl-substituted phenyl group provides additional sites for functionalization, enabling the creation of more complex molecular architectures.

From an environmental perspective, 2-(2-methylphenyl)-1,3-oxazole-4-carbaldehyde has been studied for its biodegradability and eco-friendly properties. Research indicates that it can be metabolized by certain microorganisms under specific conditions, making it a more sustainable option compared to traditional synthetic compounds.

In conclusion, 2-(2-methylphenyl)-1,3-oxazole-4-carbaldehyde (CAS No. 154136-88-6) is a multifaceted compound with significant potential across various industries. Its unique structure, reactivity, and versatility make it an invaluable tool in modern chemistry. As research continues to uncover new applications and properties of this compound, its role in advancing science and technology is expected to grow further.

• 885273-15-4(2-(3-chlorophenyl)-1,3-oxazole-4-carbaldehyde)
• 885273-23-4(2-(3-ethylphenyl)-1,3-oxazole-4-carbaldehyde)
• 885273-32-5(2-(3,4-dimethylphenyl)-1,3-oxazole-4-carbaldehyde)
• 877-39-4(4-methyl-2-phenyl-1,3-oxazole)
• 23012-16-0(2-phenyl-1,3-oxazole-4-carboxylic acid)
• 885272-95-7(2-(3-fluorophenyl)-1,3-oxazole-4-carbaldehyde)
• 885273-03-0(4-Oxazolecarboxaldehyde,2-(3-bromophenyl)-)
• 885273-74-5(4-Oxazolecarboxylicacid, 2-(3,5-dimethylphenyl)-)
• 154136-89-7(4-Oxazolecarboxaldehyde,2-(3-methylphenyl)-)
• 154136-90-0(4-Oxazolecarboxaldehyde,2-(4-methoxyphenyl)-)