Cas no 153877-56-6 (3,5-Difluorobenzhydrol)

3,5-Difluorobenzhydrol is a fluorinated benzhydrol derivative characterized by the presence of two fluorine atoms at the 3 and 5 positions of the benzene ring. This structural feature enhances its utility as a versatile intermediate in organic synthesis, particularly in the preparation of pharmaceuticals, agrochemicals, and specialty materials. The electron-withdrawing nature of the fluorine substituents influences its reactivity, making it valuable for cross-coupling reactions, nucleophilic substitutions, and other transformations. Its crystalline solid form and well-defined purity ensure consistent performance in synthetic applications. The compound’s stability and compatibility with diverse reaction conditions further underscore its importance in fine chemical and medicinal chemistry research.
3,5-Difluorobenzhydrol structure
3,5-Difluorobenzhydrol structure
Product Name:3,5-Difluorobenzhydrol
CAS No:153877-56-6
MF:C13H10F2O
MW:220.214710712433
CID:138369
PubChem ID:2758253
Update Time:2025-11-02

3,5-Difluorobenzhydrol Chemical and Physical Properties

Names and Identifiers

    • 3,5-Difluorobenzhydrol
    • 1-(3,5-Difluorophenyl)ethan-1-ol
    • 1-(3,5-DIFLUOROPHENYL)ETHANOL
    • 3,5-DIFLUOROPHENYLMETHYLCARBINOL
    • (3,5-difluorophenyl)-phenylmethanol
    • (3,5-difluorophenyl)(phenyl)methanol
    • Benzenemethanol, 3,5-difluoro-a-phenyl-
    • SCHEMBL12065137
    • AKOS010334771
    • MFCD06201256
    • 153877-56-6
    • DTXSID70934868
    • 3,5-Difluoro-alpha-Phenyl-Benzenemethanol
    • MDL: MFCD06201256
    • Inchi: 1S/C13H10F2O/c14-11-6-10(7-12(15)8-11)13(16)9-4-2-1-3-5-9/h1-8,13,16H
    • InChI Key: MZBBRGLZQRMJPL-UHFFFAOYSA-N
    • SMILES: FC1C=C(C=C(C=1)C(C1C=CC=CC=1)O)F

Computed Properties

  • Exact Mass: 158.05400
  • Monoisotopic Mass: 220.06997126g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 16
  • Rotatable Bond Count: 2
  • Complexity: 206
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 1
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 2.9
  • Topological Polar Surface Area: 20.2

Experimental Properties

  • PSA: 20.23000
  • LogP: 2.01810

3,5-Difluorobenzhydrol Security Information

  • HazardClass:IRRITANT

3,5-Difluorobenzhydrol Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
Fluorochem
022423-1g
3,5-Difluorobenzhydrol
153877-56-6 97%
1g
£333.00 2022-03-01
Fluorochem
022423-5g
3,5-Difluorobenzhydrol
153877-56-6 97%
5g
£709.00 2022-03-01
Fluorochem
022423-25g
3,5-Difluorobenzhydrol
153877-56-6 97%
25g
£1544.00 2022-03-01
A FA AI SHA , SAI MO FEI SHI ER KE JI QI XIA GONG SI
H31848-1g
3,5-Difluorobenzhydrol, 95%
153877-56-6 95%
1g
¥1162.00 2023-03-01
A FA AI SHA , SAI MO FEI SHI ER KE JI QI XIA GONG SI
H31848-5g
3,5-Difluorobenzhydrol, 95%
153877-56-6 95%
5g
¥3884.00 2023-03-01
SHANG HAI HAO HONG Biomedical Technology Co., Ltd.
1022389-1g
3,5-Difluorobenzhydrol
153877-56-6 98%
1g
¥426.00 2023-11-21
SHANG HAI HAO HONG Biomedical Technology Co., Ltd.
1022389-5g
3,5-Difluorobenzhydrol
153877-56-6 98%
5g
¥1320.00 2023-11-21
SHANG HAI HAO HONG Biomedical Technology Co., Ltd.
1022389-10g
3,5-Difluorobenzhydrol
153877-56-6 98%
10g
¥2460.00 2023-11-21
A2B Chem LLC
AE98479-1g
Benzenemethanol, 3,5-difluoro-a-phenyl-
153877-56-6 97%
1g
$1205.00 2024-04-20
A2B Chem LLC
AE98479-5g
Benzenemethanol, 3,5-difluoro-a-phenyl-
153877-56-6 97%
5g
$2831.00 2024-04-20

Additional information on 3,5-Difluorobenzhydrol

Exploring the Versatile Applications and Properties of 3,5-Difluorobenzhydrol (CAS No. 153877-56-6)

3,5-Difluorobenzhydrol (CAS No. 153877-56-6) is a fluorinated aromatic alcohol that has garnered significant attention in pharmaceutical and material science research. This compound, characterized by its two fluorine atoms at the 3 and 5 positions of the benzene ring, exhibits unique chemical properties that make it valuable for various industrial and academic applications. Researchers and manufacturers are increasingly interested in 3,5-Difluorobenzhydrol derivatives due to their potential in drug development and advanced material synthesis.

The molecular structure of 3,5-Difluorobenzhydrol features a benzhydrol core with fluorine substitutions, which enhance its reactivity and stability under different conditions. This structural feature is particularly advantageous in the synthesis of fluorinated pharmaceutical intermediates, a rapidly growing segment in the chemical industry. The demand for high-purity 3,5-Difluorobenzhydrol has surged, driven by its role in creating innovative therapeutic agents and specialty chemicals.

One of the most compelling applications of 3,5-Difluorobenzhydrol is in the development of next-generation drug candidates. Fluorinated compounds are known for their ability to improve the bioavailability and metabolic stability of pharmaceuticals. As a result, 3,5-Difluorobenzhydrol suppliers are witnessing increased inquiries from biotech and pharmaceutical companies aiming to leverage its properties for novel drug formulations. The compound's versatility also extends to agrochemicals, where it serves as a key building block for crop protection agents.

In addition to its pharmaceutical relevance, 3,5-Difluorobenzhydrol is gaining traction in material science. Its fluorinated aromatic structure makes it an excellent candidate for advanced polymer synthesis and liquid crystal materials. Researchers are exploring its use in creating high-performance polymers with enhanced thermal and chemical resistance, which are critical for aerospace and electronics applications. The compound's ability to modify material properties at the molecular level positions it as a valuable asset in cutting-edge material innovation.

The synthesis and handling of 3,5-Difluorobenzhydrol require specialized expertise due to its reactive functional groups. Manufacturers emphasize the importance of strict quality control measures to ensure the compound's purity and consistency. Analytical techniques such as HPLC and NMR spectroscopy are commonly employed to verify the integrity of 3,5-Difluorobenzhydrol batches, meeting the stringent requirements of end-users in research and production.

Environmental and regulatory considerations also play a crucial role in the commercialization of 3,5-Difluorobenzhydrol. Companies are increasingly adopting green chemistry principles to minimize the environmental impact of its production. Sustainable synthesis methods, including catalytic fluorination and solvent-free reactions, are being explored to align with global sustainability goals. This focus on eco-friendly practices enhances the compound's appeal in markets prioritizing green chemical solutions.

Market trends indicate a steady growth in the demand for 3,5-Difluorobenzhydrol, particularly in regions with robust pharmaceutical and material science sectors. North America and Europe dominate the market, driven by their advanced research infrastructure and high investment in innovative chemical applications. Meanwhile, the Asia-Pacific region is emerging as a key player, with increasing production capabilities and a growing focus on specialty fluorinated compounds.

For researchers and industry professionals seeking reliable information on 3,5-Difluorobenzhydrol, understanding its physicochemical properties is essential. The compound's solubility, melting point, and stability under various conditions are critical parameters for its successful application. Detailed technical data sheets and safety guidelines are available from reputable suppliers, ensuring safe and effective use in laboratory and industrial settings.

In conclusion, 3,5-Difluorobenzhydrol (CAS No. 153877-56-6) stands out as a multifaceted compound with significant potential across multiple industries. Its role in pharmaceutical development, material science, and green chemistry underscores its importance in modern chemical research. As innovation continues to drive demand for high-performance fluorinated compounds, 3,5-Difluorobenzhydrol is poised to remain a key player in the evolving landscape of specialty chemicals.

Recommended suppliers
Shanghai Hongxiang Biomedical Technology Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Shanghai Hongxiang Biomedical Technology Co., Ltd.
Hangzhou Cedareal Technology Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Hangzhou Cedareal Technology Co., Ltd.
Xiamen PinR Bio-tech Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Xiamen PinR Bio-tech Co., Ltd.
Shaanxi pure crystal photoelectric technology co. LTD
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
Shaanxi pure crystal photoelectric technology co. LTD
Shenzhen Jianxing Pharmaceutical Technology Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
Shenzhen Jianxing Pharmaceutical Technology Co., Ltd.