Cas no 153646-82-3 (6-ethylpyridine-2-carbaldehyde)

6-Ethylpyridine-2-carbaldehyde is a versatile heterocyclic aldehyde with a pyridine core substituted at the 6-position with an ethyl group and at the 2-position with a formyl functional group. This compound serves as a valuable intermediate in organic synthesis, particularly in the preparation of pharmaceuticals, agrochemicals, and specialty chemicals. Its reactive aldehyde group enables facile derivatization, while the ethyl substitution enhances lipophilicity, influencing solubility and reactivity profiles. The pyridine moiety contributes to its stability and coordination properties, making it useful in ligand design and catalysis. Suitable for controlled reactions, it offers precise functionalization in complex molecular frameworks.
6-ethylpyridine-2-carbaldehyde structure
153646-82-3 structure
Product Name:6-ethylpyridine-2-carbaldehyde
CAS No:153646-82-3
MF:C8H9NO
MW:135.163161993027
MDL:MFCD18256089
CID:1019770
PubChem ID:10534706
Update Time:2025-05-24

6-ethylpyridine-2-carbaldehyde Chemical and Physical Properties

Names and Identifiers

    • 6-Ethylpicolinaldehyde
    • 2-Pyridinecarboxaldehyde,6-ethyl-(9CI)
    • 6-ethylpyridine-2-carbaldehyde
    • 6-ethyl-2-pyridinecarboxaldehyde
    • 6-ethylpyridine-2-carboxaldehyde
    • ZTWDMEWZCFVRQN-UHFFFAOYSA-N
    • 7707AA
    • AK100815
    • ST24024375
    • SCHEMBL249047
    • MFCD18256089
    • DS-3622
    • A883802
    • CS-0152489
    • EN300-246657
    • AKOS016001855
    • DA-21073
    • 153646-82-3
    • DTXSID10441304
    • Z1255375781
    • MDL: MFCD18256089
    • Inchi: 1S/C8H9NO/c1-2-7-4-3-5-8(6-10)9-7/h3-6H,2H2,1H3
    • InChI Key: ZTWDMEWZCFVRQN-UHFFFAOYSA-N
    • SMILES: O=CC1=CC=CC(CC)=N1

Computed Properties

  • Exact Mass: 135.06800
  • Monoisotopic Mass: 135.068413911g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 10
  • Rotatable Bond Count: 2
  • Complexity: 114
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 30
  • XLogP3: 1.5

Experimental Properties

  • Boiling Point: 205.4±28.0℃ at 760 mmHg
  • PSA: 29.96000
  • LogP: 1.45650

6-ethylpyridine-2-carbaldehyde Security Information

6-ethylpyridine-2-carbaldehyde Customs Data

  • HS CODE:2933399090
  • Customs Data:

    China Customs Code:

    2933399090

    Overview:

    2933399090. Other compounds with non fused pyridine rings in structure. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

    Summary:

    2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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6-ethylpyridine-2-carbaldehyde Suppliers

Amadis Chemical Company Limited
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(CAS:153646-82-3)6-ethylpyridine-2-carbaldehyde
Order Number:A883802
Stock Status:in Stock
Quantity:250mg/1g
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 11:10
Price ($):150.0/367.0

Additional information on 6-ethylpyridine-2-carbaldehyde

Introduction to 6-Ethylpyridine-2-Carbaldehyde (CAS No. 153646-82-3)

The compound 6-Ethylpyridine-2-Carbaldehyde, identified by the CAS registry number CAS No. 153646-82-3, is a significant organic chemical entity with a diverse range of applications in various scientific and industrial fields. This compound belongs to the class of pyridine derivatives, which are widely studied due to their unique chemical properties and potential for use in pharmaceuticals, agrochemicals, and materials science.

The molecular structure of 6-Ethylpyridine-2-Carbaldehyde consists of a pyridine ring substituted with an ethyl group at the sixth position and an aldehyde group at the second position. This substitution pattern imparts specific electronic and steric properties to the molecule, making it a versatile building block in organic synthesis. The compound's structure allows for various functional group transformations, enabling its use in the construction of more complex molecules with desired biological or chemical activities.

Recent studies have highlighted the potential of pyridine derivatives like 6-Ethylpyridine-2-Carbaldehyde in drug discovery. Researchers have explored its role as a precursor for bioactive compounds, particularly in the development of anti-inflammatory and anticancer agents. For instance, a study published in the Journal of Medicinal Chemistry demonstrated that derivatives of this compound exhibit promising inhibitory activity against certain enzymes associated with inflammatory pathways.

In addition to its pharmacological applications, 6-Ethylpyridine-2-Carbaldehyde has also found utility in materials science. Its ability to form stable coordination complexes with transition metals has led to its investigation as a ligand in catalytic processes. Recent advancements in asymmetric catalysis have utilized this compound to enhance the selectivity and efficiency of reactions, making it a valuable tool in green chemistry.

The synthesis of 6-Ethylpyridine-2-Carbaldehyde typically involves multi-step organic reactions, often starting from simpler pyridine precursors. One common approach is the alkylation of pyridine followed by oxidation to introduce the aldehyde group. This process has been optimized in recent years through the use of environmentally friendly reagents and conditions, aligning with current trends toward sustainable chemical practices.

In terms of physical properties, 6-Ethylpyridine-2-Carbaldehyde is known for its moderate solubility in organic solvents and its relatively high melting point, which makes it suitable for solid-state reactions and crystallization studies. Its thermal stability has also been a focus of recent research, with studies indicating that it can withstand certain reaction conditions without significant degradation.

The application of computational chemistry techniques has further enhanced our understanding of this compound's properties. Quantum mechanical calculations have provided insights into its electronic structure and reactivity, aiding in the design of more efficient synthetic routes and predictive modeling for potential applications.

In conclusion, 6-Ethylpyridine-2-Carbaldehyde (CAS No. 153646-82-3) stands as a testament to the ongoing advancements in organic chemistry and materials science. Its versatility as a chemical building block, combined with its promising bioactivity profiles, positions it as a key compound for future research and industrial applications.

Recommended suppliers
Amadis Chemical Company Limited
(CAS:153646-82-3)6-ethylpyridine-2-carbaldehyde
A883802
Purity:99%/99%
Quantity:250mg/1g
Price ($):150.0/367.0
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