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• 2. Dissociation of large gaseous serine clusters produces abundant protonated serine octamer
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• 3. Dissociative dynamics of O2 on Ag(110)?
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• 4. Evolution of dealloying induced strain in nanoporous gold crystals?
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• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Phenoxy compounds

Comprehensive Guide to 2,3-Difluorophenyl chloroformate (CAS No. 1520845-30-0): Properties, Applications, and Market Insights

2,3-Difluorophenyl chloroformate (CAS No. 1520845-30-0) is a specialized organofluorine compound widely used in pharmaceutical and agrochemical research. This compound belongs to the class of aryl chloroformates, which are known for their reactivity and versatility in organic synthesis. With the increasing demand for fluorinated building blocks in drug discovery, 2,3-Difluorophenyl chloroformate has gained significant attention for its unique properties and applications.

The molecular structure of 2,3-Difluorophenyl chloroformate features two fluorine atoms at the 2 and 3 positions of the phenyl ring, which significantly influences its electronic and steric properties. This structural characteristic makes it an excellent candidate for cross-coupling reactions and protecting group chemistry. Researchers often utilize this compound as a key intermediate in the synthesis of more complex molecules, particularly in the development of active pharmaceutical ingredients (APIs).

One of the most notable applications of 2,3-Difluorophenyl chloroformate is in the preparation of carbamate derivatives, which are essential in medicinal chemistry. The compound's ability to react with amines to form stable carbamates makes it invaluable in the design of enzyme inhibitors and receptor modulators. Recent studies have highlighted its role in the synthesis of potential anticancer agents and central nervous system (CNS) drugs, aligning with the growing interest in targeted therapies.

From a market perspective, the demand for 2,3-Difluorophenyl chloroformate is driven by the expanding pharmaceutical and agrochemical industries. The compound's compatibility with high-throughput screening and combinatorial chemistry techniques has made it a preferred choice for researchers exploring new drug candidates. Additionally, its stability under various reaction conditions ensures consistent performance in multi-step synthetic routes.

Environmental and safety considerations are also critical when working with 2,3-Difluorophenyl chloroformate. While the compound is not classified as hazardous under standard regulations, proper handling procedures should be followed to minimize exposure. Researchers are increasingly focusing on green chemistry approaches to reduce waste and improve the sustainability of synthetic processes involving this reagent.

In conclusion, 2,3-Difluorophenyl chloroformate (CAS No. 1520845-30-0) is a versatile and valuable compound in modern synthetic chemistry. Its applications span across drug discovery, agrochemical development, and material science, making it a cornerstone in the field of fluorinated organic compounds. As research continues to uncover new uses for this reagent, its importance in the chemical industry is expected to grow significantly.

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• 841258-01-3(3,4-difluorophenyl chloroformate)
• 1250435-92-7(2-fluoro-5-methylphenyl chloroformate)
• 1388848-33-6(3,5-difluorophenyl chloroformate)
• 36919-02-5(2,3,4,5,6-pentafluorophenyl carbonochloridate)
• 1516039-72-7(Carbonochloridic acid, 2,6-difluorophenyl ester)
• 400900-00-7(2,4-Difluorophenyl chloroformate)
• 68622-07-1(3-fluorophenyl chloroformate)
• 70093-67-3(2-Fluorophenyl Chloroformate)