Cas no 15186-48-8 ((R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde)
(R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde Chemical and Physical Properties
Names and Identifiers
-
- 2,3-O-isopropylidene- D-glyceraldehyde
- (R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde
- 2,3-O-(R)-ISOPROPYLIDENE-D-GLYCERALDEHYDE
- R-(+)-Solketaldehyde
- 2,2-Dimethyl-[1,3]-dioxolane-4-carboaldehyde
- (+)-2,2-DIMETHYL-1,3-DIOXOLANE-4-CARBOXALDEHYDE
- (R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehydeDiscontinued, Unstable
- (R)-2,2-dimethyl-1,3-dioxolane-4-carbaldehyde
- (4R)-2,2-dimethyl-1,3-dioxolane-4-carbaldehyde
- (R)-(+)-Glyceraldehyde acetonide
- (R)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde(needs distilling as oligomeric form)
- (R)-Glyceraldehyde Acetonid
- (R)-Isopropylideneglyceraldehyde
- NSC 89869
- 1,3-Dioxolane-4-carboxaldehyde,2,2-dimethyl-, (R)-
- 1,3-Dioxolane-4-carboxaldehyde, 2,2-dimethyl-, D- (8CI)
- (4R)-2,2-Dimethyl-1,3-dioxolan-4-carboxaldehyde
- (4R)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde
- (R)-(+)-2,2-Dimethyl-1,3-dioxolan-4-carboxaldehyde
- (R)-1,2-Isopropylideneglyceraldehyde
- (R)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde
- (R)-2,3-(Isopropylidenedioxy)propanal
- (R)-2,3-Isopropylidene-D-glyceradehyde
- (R)-2,3-O-Isopropylideneglyceraldehyde
- (R)-Glyceraldehyde acetonide
- 2,3-Di-O-isopropylidene-D-glyceraldehyde
- 2,3-O-(1-Methylethylidene)-D-glyceraldehyde
- 2,3-O-Isopropylidene-(R)-glyceraldehyde
- D-Glyceraldehyde acetonide
- Isopropylidene-D-glyceraldehyde
- EOS-61843
- (R)-(+)-2,2-Dimethyl
- R-Glyceraldehyde-acetonide
- D-Glyceraldehyde-acetonide
- (R)-acetone glyceraldehyde
- D-(R)-GLYCERALDEHYDE ACETONIDE
- (R)-(+)-2,2-Dimethyl-1,3-Dioxo
- (R)-(+)-Glyceraldehydeacetonide
- 2,3-O-Isopropylidene-D-glyceraldehyde
- YSGPYVWACGYQDJ-YFKPBYRVSA-N
- 1,3-Dioxolane-4-carboxaldehyde, 2,2-dimethyl-, (R)-
- Acetone D-glyceraldehyde
- 1,3-Dioxolane-4-carboxaldehyde, 2,2-dimethyl-, (4R)-
- (4r)-2,2-dimethyl-1,3-dioxolan-4-carbaldehyd
- NSC89869
- PubChe
- AKOS015842119
- AS-40659
- (4R)-2,2-Dimethyl-1,3-dioxolane-4-carbaldehyde (50% in DCM)
- (R)-2,2-DIMETHYL-[1,3]DIOXOLANE-4-CARBALDEHYDE
- A809231
- (R)-2,2-Dimethyl-1.3-dioxolane-4-carboxaldehyde
- EN300-44148
- MFCD00269682
- 15186-48-8
- BCP08512
- W-200128
- (R)-2,2-dimethyl-1,3-dioxolane-4-carbaldehyde(50% in Chlorocyclohexane)
- Z446488674
- AC-33687
- AC-11082
- NSC-89869
- SCHEMBL367022
- 2,2-Dimethyl-1,3-dioxolane-4-carbaldehyde, (D)-
- (R)-(+)-2,2,Dimethyl-1,3-dioxolane-4-carboxaldehyde
- AKOS005146060
- CS-0009587
- GEO-01173
- DB-005016
- DB-009107
-
- MDL： MFCD00269682
- Inchi： 1S/C6H10O3/c1-6(2)8-4-5(3-7)9-6/h3,5H,4H2,1-2H3/t5-/m0/s1
- InChI Key： YSGPYVWACGYQDJ-YFKPBYRVSA-N
- SMILES： O1[C@@H](C=O)COC1(C)C
Computed Properties
- Exact Mass: 130.06300
- Monoisotopic Mass: 130.063
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 3
- Heavy Atom Count: 9
- Rotatable Bond Count: 1
- Complexity: 120
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 1
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Surface Charge: 0
- Tautomer Count: 2
- XLogP3: 0
- Topological Polar Surface Area: 35.5
Experimental Properties
- Color/Form: Not available
- Density: 1.045?g/mL?at 25?°C(lit.)
- Boiling Point: 139?°C(lit.)
- Flash Point: Fahrenheit: 143.6 ° f
Celsius: 62 ° c - Refractive Index: n20/D 1.454(lit.)
- Solubility: Difficult to mix.
- PSA: 35.53000
- LogP: 0.33680
- Specific Rotation: 53.8 o (c=2, CHCl3)
- Optical Activity: [α]22/D +53.8°, c =?2 in chloroform
- Solubility: Not available
(R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde Security Information
- Signal Word：Warning
- Hazard Statement： H227-H315-H319-H335
- Warning Statement： P305+P351+P338
- WGK Germany：3
- HazardClass：6.1
- Storage Condition：?20°C
(R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde Customs Data
- HS CODE：2932999099
- Customs Data：
China Customs Code:
2932999099Overview:
2932999099. Other heterocyclic compounds containing only oxygen heteroatoms. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%
Declaration elements:
Product Name, component content, use to
Summary:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
(R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
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| Fluorochem | 038227-5g |
R)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde 50% in Methylene chloride |
15186-48-8 | 95% | 5g |
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| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | R134306-100g |
(R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde |
15186-48-8 | 95% | 100g |
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| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | R134306-1g |
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15186-48-8 | 95% | 1g |
￥30.90 | 2023-09-01 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | R134306-25g |
(R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde |
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￥175.90 | 2023-09-01 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | R134306-5g |
(R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde |
15186-48-8 | 95% | 5g |
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| Chemenu | CM328312-1000g |
(4R)-2,2-dimethyl-1,3-dioxolane-4-carbaldehyde |
15186-48-8 | 95% | 1000g |
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| abcr | AB457386-5 g |
2,3-Isopropylidene-(R)-glyceraldehyde (50% solution in dichloromethane); . |
15186-48-8 | 5g |
€46.60 | 2022-03-24 | ||
| abcr | AB457386-25 g |
2,3-Isopropylidene-(R)-glyceraldehyde (50% solution in dichloromethane); . |
15186-48-8 | 25g |
€77.30 | 2022-03-24 | ||
| abcr | AB457386-100 g |
2,3-Isopropylidene-(R)-glyceraldehyde (50% solution in dichloromethane); . |
15186-48-8 | 100g |
€176.50 | 2022-03-24 |
(R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde Suppliers
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(R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde Related Literature
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Amandine Altmayer-Henzien,Valérie Declerck,David J. Aitken,Ewen Lescop,Denis Merlet,Jonathan Farjon Org. Biomol. Chem., 2013,11, 7611-7615
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Byungho Lim,Jaewon Jin,Jin Yoo,Seung Yong Han,Kyeongyeol Kim,Sungah Kang,Nojin Park,Sang Moon Lee,Hae Jin Kim,Seung Uk Son Chem. Commun., 2014,50, 7723-7726
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J. Matthew Kurley,Phillip W. Halstenberg,Abbey McAlister,Stephen Raiman,Richard T. Mayes RSC Adv., 2019,9, 25602-25608
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A. B. F. da Silva,K. Capelle Phys. Chem. Chem. Phys., 2009,11, 4564-4569
Additional information on (R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde
Comprehensive Analysis of (R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde (CAS No. 15186-48-8)
(R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde (CAS No. 15186-48-8) is a highly versatile chiral building block widely used in organic synthesis, pharmaceuticals, and fragrance industries. This compound, characterized by its dioxolane ring and aldehyde functional group, plays a critical role in asymmetric synthesis due to its stereochemical purity and reactivity. Researchers and manufacturers value it for its ability to introduce chiral centers into complex molecules, making it indispensable in the production of optically active intermediates.
The growing demand for enantiomerically pure compounds in drug development has spotlighted (R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde. Its CAS No. 15186-48-8 is frequently searched in academic and industrial databases, reflecting its relevance in green chemistry and sustainable synthesis. Recent trends show increased interest in its applications for biocatalysis and flow chemistry, aligning with the global shift toward eco-friendly manufacturing processes.
One of the most common queries about this compound revolves around its synthetic routes and scalability. The dioxolane-protected aldehyde moiety offers stability under acidic and basic conditions, making it ideal for multi-step reactions. Its chiral auxiliary properties are leveraged in the synthesis of natural products and active pharmaceutical ingredients (APIs), such as antiviral and anticancer agents. Users often search for alternative catalysts or solvent-free methods to optimize its production, highlighting the intersection of cost-efficiency and environmental responsibility.
In the fragrance industry, (R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde is prized for its role in creating stereospecific aroma compounds. Its volatility and stereochemical integrity make it a preferred choice for high-end perfumes and flavor enhancers. Searches for chiral aldehydes in perfumery often lead to this compound, underscoring its cross-industry appeal.
From a technical standpoint, the compound’s physical properties—such as melting point, boiling point, and optical rotation—are well-documented, aiding in quality control and regulatory compliance. Analytical techniques like HPLC, NMR, and GC-MS are routinely employed to verify its purity, a topic frequently explored in method development forums. Additionally, its storage conditions and handling precautions are often queried, emphasizing the need for precise technical guidance.
As the pharmaceutical and chemical industries evolve, CAS No. 15186-48-8 continues to attract attention for its synergistic applications in catalysis and material science. Innovations in continuous flow systems and enzyme-mediated reactions further expand its utility, addressing both efficiency and sustainability goals. This aligns with broader market trends favoring high-value chiral synthons and low-waste processes.
In summary, (R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde (CAS No. 15186-48-8) stands as a cornerstone in modern synthetic chemistry. Its multifaceted applications, coupled with rising interest in stereoselective synthesis and green chemistry, ensure its enduring relevance. Whether for academic research, industrial production, or niche applications like fragrances, this compound exemplifies the convergence of innovation and practicality.
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