Cas no 150879-48-4 (2-amino-5-chloro-n-methoxy-n-methylbenzamide)

2-Amino-5-chloro-N-methoxy-N-methylbenzamide is a versatile intermediate in organic synthesis, particularly valued for its role in pharmaceutical and agrochemical applications. Its molecular structure, featuring both amino and chloro substituents on the aromatic ring, along with the N-methoxy-N-methylamide functional group, makes it a useful building block for the development of bioactive compounds. The compound exhibits favorable reactivity in coupling and condensation reactions, enabling efficient derivatization. Its stability under standard storage conditions and compatibility with common solvents further enhance its utility in research and industrial processes. This intermediate is particularly relevant in the synthesis of compounds targeting specific biological pathways.
2-amino-5-chloro-n-methoxy-n-methylbenzamide structure
150879-48-4 structure
Product Name:2-amino-5-chloro-n-methoxy-n-methylbenzamide
CAS No:150879-48-4
MF:C9H11ClN2O2
MW:214.648841142654
MDL:MFCD12095383
CID:1322788
PubChem ID:22226605
Update Time:2025-05-20

2-amino-5-chloro-n-methoxy-n-methylbenzamide Chemical and Physical Properties

Names and Identifiers

    • 2-amino-5-chloro-n-methoxy-n-methylbenzamide
    • 6-amino-3-chloro-N-methoxy-N-methylbenzamide;2-AMINO-5-CHLORO-N-METHOXY-N-METHYL-BENZAMIDE;N-methyl-N-methyloxy-2-amino-5-chlorobenzamide;
    • 2-Amino-5-chloro-N-methoxy-N-methyl-benzamide
    • MFCD12095383
    • AKOS009816910
    • 150879-48-4
    • Benzamide, 2-amino-5-chloro-N-methoxy-N-methyl-
    • SB33802
    • N-methyl-N-methyloxy-2-amino-5-chlorobenzamide
    • N-methyl-N-methyloxy-2-amino-5-chloro-benzamide
    • AS-42934
    • YYFLGRSYBQKTTR-UHFFFAOYSA-N
    • DA-09991
    • SCHEMBL26732
    • DTXSID20623598
    • MDL: MFCD12095383
    • Inchi: 1S/C9H11ClN2O2/c1-12(14-2)9(13)7-5-6(10)3-4-8(7)11/h3-5H,11H2,1-2H3
    • InChI Key: YYFLGRSYBQKTTR-UHFFFAOYSA-N
    • SMILES: ClC1C=CC(=C(C=1)C(N(C)OC)=O)N

Computed Properties

  • Exact Mass: 214.05100
  • Monoisotopic Mass: 214.051
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 14
  • Rotatable Bond Count: 3
  • Complexity: 213
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 1.6
  • Topological Polar Surface Area: 55.6A^2

Experimental Properties

  • PSA: 55.56000
  • LogP: 2.13680

2-amino-5-chloro-n-methoxy-n-methylbenzamide Pricemore >>

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2-amino-5-chloro-n-methoxy-n-methylbenzamide Production Method

Additional information on 2-amino-5-chloro-n-methoxy-n-methylbenzamide

Comprehensive Guide to 2-Amino-5-chloro-N-methoxy-N-methylbenzamide (CAS No. 150879-48-4): Properties, Applications, and Market Insights

2-Amino-5-chloro-N-methoxy-N-methylbenzamide (CAS No. 150879-48-4) is a specialized organic compound widely recognized for its versatile applications in pharmaceutical and agrochemical research. This compound, often referred to as ACMMB in scientific literature, belongs to the benzamide class and features a unique molecular structure that makes it valuable in synthetic chemistry. Researchers and industry professionals frequently search for 2-Amino-5-chloro-N-methoxy-N-methylbenzamide suppliers, ACMMB synthesis methods, and its role in drug development, reflecting its growing importance.

The molecular formula of 2-Amino-5-chloro-N-methoxy-N-methylbenzamide is C9H11ClN2O2, with a molecular weight of 214.65 g/mol. Its structure includes an amino group (-NH2) at the 2-position and a chloro substituent (-Cl) at the 5-position of the benzene ring, along with a methoxy-N-methylamide side chain. This configuration contributes to its reactivity and functionality in various chemical reactions. Recent trends show increased interest in 150879-48-4 solubility data and ACMMB stability under different conditions, highlighting the need for detailed technical specifications.

In pharmaceutical applications, 2-Amino-5-chloro-N-methoxy-N-methylbenzamide serves as a key intermediate in the synthesis of biologically active molecules. Its structural features make it particularly useful in developing enzyme inhibitors and receptor modulators. Many researchers are investigating its potential in targeted drug delivery systems and small molecule therapeutics, aligning with current industry focus on precision medicine. The compound's N-methoxy-N-methylamide moiety is especially valuable for creating prodrugs with improved bioavailability.

The agrochemical sector also benefits from CAS 150879-48-4, where it functions as a building block for crop protection agents. Its chlorine and amino groups contribute to the herbicidal and fungicidal activities of derived compounds. With growing global demand for sustainable agriculture solutions, the role of ACMMB derivatives in developing environmentally friendly pesticides has gained attention. Industry reports indicate rising searches for chlorinated benzamide applications in agriculture and green chemistry approaches using such intermediates.

From a market perspective, 2-Amino-5-chloro-N-methoxy-N-methylbenzamide has seen steady demand growth, particularly from Asia-Pacific regions where pharmaceutical and agrochemical production is expanding. Current market analysis reveals increased queries about 150879-48-4 price trends and bulk purchase options, suggesting its commercial significance. Manufacturers are focusing on improving synthesis efficiency to meet quality standards while reducing production costs, addressing common search terms like high purity ACMMB synthesis and cost-effective benzamide production.

Quality control is paramount when working with CAS No. 150879-48-4. Analytical methods such as HPLC, GC-MS, and NMR spectroscopy are essential for verifying purity and identifying impurities. Recent advancements in analytical chemistry techniques have enabled more precise characterization of this compound, responding to industry needs for reliable quality assessment protocols. Regulatory compliance documentation, including Certificate of Analysis (CoA) and material safety data, remains a top priority for buyers and users.

Storage and handling recommendations for 2-Amino-5-chloro-N-methoxy-N-methylbenzamide typically suggest keeping the material in cool, dry conditions away from direct sunlight. Proper packaging in sealed containers prevents moisture absorption and degradation. These practical considerations address frequently asked questions about ACMMB shelf life and storage best practices, which are particularly relevant for laboratory managers and procurement specialists.

Future research directions for 150879-48-4 include exploring its potential in novel therapeutic areas and developing more sustainable production methods. The compound's versatility continues to attract scientific interest, with emerging studies investigating its use in bioconjugation chemistry and material science applications. As the chemical industry evolves toward greener processes, innovations in catalytic amidation reactions and solvent-free synthesis of such benzamides are gaining traction.

For researchers considering 2-Amino-5-chloro-N-methoxy-N-methylbenzamide for their projects, numerous commercial sources offer the compound in various quantities and purity grades. Comparison of technical grade vs. pharmaceutical grade ACMMB and evaluation of supplier reliability are common considerations. The development of custom synthesis services for derivatives and analogs further expands the possibilities for utilizing this valuable chemical building block.

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