Cas no 1508-46-9 (Scopine Methobromide)

Scopine Methobromide is a quaternary ammonium derivative of scopine, primarily recognized for its anticholinergic properties. This compound acts as a competitive antagonist at muscarinic acetylcholine receptors, making it useful in research and pharmaceutical applications where precise modulation of cholinergic signaling is required. Its quaternary structure limits its ability to cross the blood-brain barrier, rendering it peripherally selective. Scopine Methobromide is often employed in studies investigating smooth muscle relaxation, gastrointestinal motility, or bronchial dilation. The compound’s stability and well-defined pharmacological profile make it a reliable reference standard in analytical and preclinical research. It is typically handled under controlled conditions due to its hygroscopic nature.
Scopine Methobromide structure
Scopine Methobromide structure
Product Name:Scopine Methobromide
CAS No:1508-46-9
MF:C9H16BrNO2
MW:250.132842063904
CID:883239
Update Time:2025-10-28

Scopine Methobromide Chemical and Physical Properties

Names and Identifiers

    • Scopine Methobromide
    • &nbsp
    • AGN-PC-004UVP
    • 6exo,7exo-epoxy-3endo-hydroxy-8,8-dimethyl-nortropanium,bromide
    • methylscopinium bromide
    • N-methylsconinium bromide
    • N-methylscopinium bromide
    • N-methylscopolaminium bromide
    • (1R,2R,4S,5S,7s)-7-Hydroxy-9,9-dimethyl-3-oxa-9-azoniatricyclo [3.3.1.02,4] nonane bromide
    • BEA 2180 alcohol
    • BEA 2180 BR
    • NSC120513
    • 7-Hydroxy-9,9-dimethyl-3-oxa-9-azatricyclo[3.3.1.0~2,4~]nonan-9-ium bromide
    • Inchi: 1S/C9H16NO2.BrH/c1-10(2)6-3-5(11)4-7(10)9-8(6)12-9;/h5-9,11H,3-4H2,1-2H3;1H/q+1;/p-1
    • InChI Key: IKDFZBCJDLZSNH-UHFFFAOYSA-M
    • SMILES: [Br-].O1C2C1C1CC(CC2[N+]1(C)C)O

Computed Properties

  • Exact Mass: 249.03600
  • Monoisotopic Mass: 249.03644 g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 13
  • Rotatable Bond Count: 0
  • Complexity: 209
  • Covalently-Bonded Unit Count: 2
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 4
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 32.8
  • Molecular Weight: 250.13

Experimental Properties

  • PSA: 32.76000
  • LogP: -3.30150

Scopine Methobromide Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
TRC
S199985-2.5mg
Scopine Methobromide
1508-46-9
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$ 176.00 2023-09-06
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$ 283.00 2023-09-06
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A2B Chem LLC
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$392.00 2024-04-20
A2B Chem LLC
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$2301.00 2024-04-20
SHENG KE LU SI SHENG WU JI SHU
sc-472781-2.5mg
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¥2407.00 2023-09-05
SHENG KE LU SI SHENG WU JI SHU
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Additional information on Scopine Methobromide

Scopine Methobromide: A Comprehensive Overview

Scopine Methobromide, also known by its CAS number 1508-46-9, is a compound of significant interest in the fields of pharmacology and organic chemistry. This compound has garnered attention due to its unique properties and potential applications in various therapeutic areas. In this article, we will delve into the characteristics, synthesis, and recent advancements associated with Scopine Methobromide, providing a detailed and up-to-date analysis.

The chemical structure of Scopine Methobromide is a derivative of scopine, which itself is a naturally occurring alkaloid. The methobromide functional group adds distinct properties to the molecule, influencing its pharmacokinetics and bioavailability. Recent studies have highlighted the importance of understanding the stereochemistry of this compound, as it plays a crucial role in determining its biological activity. Researchers have employed advanced spectroscopic techniques, such as NMR and X-ray crystallography, to elucidate the exact configuration of Scopine Methobromide, paving the way for more precise synthesis methods.

In terms of pharmacological activity, Scopine Methobromide has been investigated for its potential as a neuromuscular agent. Preclinical studies have demonstrated its ability to modulate cholinergic pathways, making it a promising candidate for treating conditions such as myasthenia gravis and other neuromuscular disorders. Moreover, recent clinical trials have explored its efficacy in alleviating symptoms associated with chronic pain syndromes. These findings underscore the versatility of Scopine Methobromide in addressing diverse therapeutic needs.

The synthesis of Scopine Methobromide has also been a focal point of recent research. Traditional methods often involved multi-step processes with low yields, but advancements in catalytic chemistry have enabled more efficient synthetic routes. For instance, the use of palladium-catalyzed cross-coupling reactions has significantly improved the yield and purity of Scopine Methobromide. Additionally, green chemistry principles have been integrated into these processes to minimize environmental impact, aligning with current sustainability goals.

Beyond its pharmacological applications, Scopine Methobromide has found utility in analytical chemistry as a chiral resolving agent. Its ability to induce enantioselectivity in chromatographic separations has made it an invaluable tool in drug discovery and quality control processes. Recent innovations in high-performance liquid chromatography (HPLC) techniques have further enhanced the application of Scopine Methobromide, enabling faster and more accurate analysis of complex mixtures.

In conclusion, Scopine Methobromide, with its CAS number 1508-46-9, stands as a testament to the progress in chemical research and development. Its diverse applications across pharmacology, analytical chemistry, and synthetic methodology highlight its significance in both academic and industrial settings. As research continues to uncover new facets of this compound, it is poised to play an even greater role in advancing healthcare solutions.

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