• 1. An automatic method for the determination of anionic surface-active material in water
  Analyst, 1966,91, 113-118
• 2. An investigation of new infrared nonlinear optical material: BaCdSnSe4, and three new related centrosymmetric compounds: Ba2SnSe4, Mg2GeSe4, and Ba2Ge2S6?
  Kui Wu,Zhihua Yang,Shilie Pan Dalton Trans., 2015,44, 19856-19864
• 3. An integrated digital microfluidic chip for multiplexed proteomic sample preparation and analysis by MALDI-MS?
  Hyejin Moon,Aaron R. Wheeler,Robin L. Garrell,Chang-Jin “CJ” Kim Lab Chip, 2006,6, 1213-1219
• 4. An Appraisal of pH triggered Bacitracin drug release, through composite hydrogel systems
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• 5. An ionic liquid promoted microwave-hydrothermal route towards highly photoluminescent carbon dots for sensitive and selective detection of iron(iii)?
  Ruili Liu,Mengping Gao,Jing Zhang,Zhilian Li,Jinyang Chen,Ping Liu,Dongqing Wu RSC Adv., 2015,5, 24205-24209

• Solvents and Organic Chemicals Organic Compounds Organic acids and derivatives Organic carbonic acids and derivatives Organic carbonic acids and derivatives
• Solvents and Organic Chemicals Organic Compounds Organic acids and derivatives Organic carbonic acids and derivatives

3-Ethylcyclohexyl Chloroformate (CAS No. 1506175-44-5): Properties, Applications, and Industry Insights

3-Ethylcyclohexyl chloroformate (CAS 1506175-44-5) is a specialized organic intermediate widely used in pharmaceutical synthesis and fine chemical production. This compound belongs to the class of chloroformate esters, known for their reactivity as acylating agents. With the increasing demand for high-purity chemical intermediates in drug development, 3-ethylcyclohexyl chloroformate applications have gained significant attention from researchers and manufacturers alike.

The molecular structure of 3-ethylcyclohexyl chloroformate features a cyclohexyl ring substituted with an ethyl group at the 3-position and a reactive chloroformate moiety. This configuration makes it particularly valuable for peptide coupling reactions and protective group chemistry. Recent studies in green chemistry approaches have explored more sustainable production methods for such intermediates, aligning with the industry's focus on environmentally friendly synthesis.

In pharmaceutical applications, CAS 1506175-44-5 serves as a key building block for various active pharmaceutical ingredients (APIs). Its unique steric properties, imparted by the ethyl-substituted cyclohexyl group, make it particularly useful in creating chiral compounds and sterically hindered molecules. The compound's reactivity profile allows for selective transformations under mild conditions, which is crucial for complex molecule synthesis in modern drug discovery programs.

The global market for 3-ethylcyclohexyl chloroformate suppliers has seen steady growth, driven by expanding research in targeted drug delivery systems and bioconjugation techniques. Quality specifications typically require high purity levels (>98%), with strict control over residual solvents and byproducts. Analytical methods such as HPLC analysis and GC-MS characterization are routinely employed to verify the compound's identity and purity for critical applications.

Storage and handling of 3-ethylcyclohexyl chloroformate 1506175-44-5 require attention to moisture sensitivity and proper ventilation. While not classified among restricted substances, appropriate laboratory safety protocols should be followed when working with this reagent. The compound is typically supplied in amber glass containers under inert atmosphere to maintain stability during transportation and storage.

Recent advancements in flow chemistry technology have opened new possibilities for the safer and more efficient use of chloroformate derivatives like 3-ethylcyclohexyl chloroformate. Continuous processing methods can minimize exposure risks while improving reaction control and yield. These developments align with the pharmaceutical industry's push toward process intensification and quality by design principles.

For researchers seeking 3-ethylcyclohexyl chloroformate price information or custom synthesis options, numerous specialty chemical providers offer the compound in various quantities. The cost typically reflects the purity grade and packaging specifications required. Some suppliers provide technical data sheets and COA documentation to support quality assurance in end-use applications.

The future outlook for CAS 1506175-44-5 applications appears promising, particularly in the development of novel therapeutic agents and specialty materials. As synthetic methodologies continue to evolve, this versatile intermediate will likely find expanded utility in asymmetric synthesis and molecular engineering applications across multiple scientific disciplines.

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