Cas no 148777-81-5 (4,5,6,7-Tetrahydropyrazolo[1,5-a]pyrimidin-3-amine)
4,5,6,7-Tetrahydropyrazolo[1,5-a]pyrimidin-3-amine is a heterocyclic amine compound featuring a fused pyrazolo-pyrimidine core. Its saturated tetrahydropyrimidine ring enhances stability and solubility, making it a versatile intermediate in pharmaceutical and agrochemical synthesis. The amine functional group at the 3-position allows for further derivatization, enabling the development of biologically active molecules. This scaffold is particularly valuable in medicinal chemistry for designing kinase inhibitors, CNS-targeting agents, and other therapeutic candidates due to its rigid yet modifiable structure. The compound’s balanced lipophilicity and hydrogen-bonding capacity contribute to improved bioavailability in drug discovery applications. Its synthetic accessibility further supports scalable production for research and industrial use.
![4,5,6,7-Tetrahydropyrazolo[1,5-a]pyrimidin-3-amine structure](https://ossimg.kuujia.com/scimg/149000/148777-81-5x500.png)
148777-81-5 structure
Product Name:4,5,6,7-Tetrahydropyrazolo[1,5-a]pyrimidin-3-amine
CAS No:148777-81-5
MF:C6H10N4
MW:138.17040014267
CID:1081926
PubChem ID:135678127
Update Time:2025-11-01
4,5,6,7-Tetrahydropyrazolo[1,5-a]pyrimidin-3-amine Chemical and Physical Properties
Names and Identifiers
-
- 4,5,6,7-Tetrahydropyrazolo[1,5-a]pyrimidin-3-amine
- 1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-3-amine
- LogP
- pyrazolo[1,5-a]pyrimidin-3-amine, 4,5,6,7-tetrahydro-
- 4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-3-amine(SALTDATA: 1.4HCl)
- DTXSID30595631
- SCHEMBL1800727
- EN300-364977
- DA-10050
- 148777-81-5
- 4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidin-3-amine
- AKOS006280338
-
- MDL： MFCD09055287
- Inchi： 1S/C6H10N4/c7-5-4-9-10-3-1-2-8-6(5)10/h4,8H,1-3,7H2
- InChI Key： KJSUUQOHRQRALU-UHFFFAOYSA-N
- SMILES： N12C(=C(C=N1)N)NCCC2
Computed Properties
- Exact Mass: 138.0907
- Monoisotopic Mass: 138.090546336g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 2
- Hydrogen Bond Acceptor Count: 4
- Heavy Atom Count: 10
- Rotatable Bond Count: 0
- Complexity: 127
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: -0.1
- Topological Polar Surface Area: 55.9?2
Experimental Properties
- PSA: 55.87
4,5,6,7-Tetrahydropyrazolo[1,5-a]pyrimidin-3-amine Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Chemenu | CM151740-1g |
4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-3-amine |
148777-81-5 | 95% | 1g |
$635 | 2021-08-05 | |
| Chemenu | CM151740-1g |
4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-3-amine |
148777-81-5 | 95% | 1g |
$*** | 2023-03-30 | |
| Enamine | EN300-364977-0.05g |
4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidin-3-amine |
148777-81-5 | 0.05g |
$24.0 | 2023-06-04 | ||
| Enamine | EN300-364977-0.1g |
4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidin-3-amine |
148777-81-5 | 0.1g |
$36.0 | 2023-06-04 | ||
| Enamine | EN300-364977-0.25g |
4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidin-3-amine |
148777-81-5 | 0.25g |
$51.0 | 2023-06-04 | ||
| Enamine | EN300-364977-0.5g |
4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidin-3-amine |
148777-81-5 | 0.5g |
$80.0 | 2023-06-04 | ||
| Enamine | EN300-364977-1.0g |
4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidin-3-amine |
148777-81-5 | 1g |
$103.0 | 2023-06-04 | ||
| Enamine | EN300-364977-2.5g |
4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidin-3-amine |
148777-81-5 | 2.5g |
$204.0 | 2023-06-04 | ||
| Enamine | EN300-364977-5.0g |
4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidin-3-amine |
148777-81-5 | 5g |
$325.0 | 2023-06-04 | ||
| Enamine | EN300-364977-10.0g |
4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidin-3-amine |
148777-81-5 | 10g |
$519.0 | 2023-06-04 |
4,5,6,7-Tetrahydropyrazolo[1,5-a]pyrimidin-3-amine Related Literature
-
Andreas Nenning,Manuel Holzmann,Jürgen Fleig,Alexander K. Opitz Mater. Adv., 2021,2, 5422-5431
-
Yong Ping Huang,Tao Tao,Zheng Chen,Wei Han,Ying Wu,Chunjiang Kuang,Shaoxiong Zhou,Ying Chen J. Mater. Chem. A, 2014,2, 18831-18837
-
Tao Wang,Yangyang Liu,Yue Deng,Hongbo Fu,Jianmin Chen Environ. Sci.: Nano, 2018,5, 1821-1833
-
Partha Laskar,Christine Dufès Nanoscale Adv., 2021,3, 6007-6026
-
Tengfei Yu,Yuehan Wu,Wei Li,Bin Li RSC Adv., 2014,4, 34134-34143
148777-81-5 (4,5,6,7-Tetrahydropyrazolo[1,5-a]pyrimidin-3-amine) Related Products
- 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
- 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
- 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
- 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
- 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
- 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
- 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
- 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
- 1449132-38-0(3-Fluoro-5-(2-fluoro-5-methylbenzylcarbamoyl)benzeneboronic acid)
- 2034271-14-0(2-(1H-indol-3-yl)-N-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}acetamide)
Recommended suppliers
Jiangsu Xinsu New Materials Co., Ltd
Gold Member
Audited Supplier
CN Supplier
Bulk
Shandong Feiyang Chemical Co., Ltd
Gold Member
Audited Supplier
CN Supplier
Bulk
Suzhou Senfeida Chemical Co., Ltd
Gold Member
Audited Supplier
CN Supplier
Bulk
Zhangzhou Sinobioway Peptide Co.,Ltd.
Gold Member
Audited Supplier
CN Supplier
Reagent
Xiamen PinR Bio-tech Co., Ltd.
Gold Member
Audited Supplier
CN Supplier
Bulk
