Cas no 1482-98-0 (L-2,4-Diaminobutyric acid hydrochloride)
L-2,4-Diaminobutyric acid hydrochloride Chemical and Physical Properties
Names and Identifiers
-
- Butanoic acid,2,4-diamino-, hydrochloride (1:1), (2S)-
- (2S)-2,4-diaminobutanoic acid,hydrochloride
- H-dab-oh·hcl
- L-2 4-DIAMINOBUTYRIC ACID MONOHYDRO-CHLO
- L-2,4-DIAMINOBUTYRIC ACID MONOHYDROCHLORIDE
- (2S)-2,4-diaminobutanoic acid,chloride
- (L) 2,4-diaminobutyric acid dihydrochloride
- (S)-(+)-2,4-diaminobutanoic acid dihydrochloride
- (S)-(+)-2,4-diaminobutyric acid dihydrochloride
- L-alpha,gamma-Diaminobutyric acid monohydrochloride
- (s)-(+)-2,4-diaminobutanoicacidhydrochloride
- (S)-2,4-Diaminobutanoic acid monohydrochloride
- Butanoic acid, 2,4-diaMino-, Monohydrochloride, (S)-
- GS-3429
- 1482-98-0
- (2S)-2,4-diaminobutanoic acid;hydrochloride
- (s)-(+)-2,4-diaminobutyric acid hydrochloride
- DTXSID20583426
- MFCD01632031
- CS-0447015
- (2S)-2,4-Diaminobutanoic acid--hydrogen chloride (1/1)
- L-2,4-Diaminobutyric acid hydrochloride
- AKOS024386272
- H-Dab-OH hydrochloride
- (2S)-2,4-diaminobutanoic acid hydrochloride
- (s)-2,4-diaminobutanoic acid hydrochloride
- AT29795
- L-2,4-Diaminobutyric acid monohydrochloride, >=98.0% (AT), >=98.0% (TLC)
- H-Dab-OH.HCl
- SCHEMBL2462827
- (2S)-2,4-diaminobutanoicacidhydrochloride
- (2S)-2,4-Diaminobutanoic Acid HCl
-
- MDL: MFCD01632031
- Inchi: 1S/C4H10N2O2.ClH/c5-2-1-3(6)4(7)8;/h3H,1-2,5-6H2,(H,7,8);1H/t3-;/m0./s1
- InChI Key: BFPDKDOFOZVSLY-DFWYDOINSA-N
- SMILES: Cl.OC([C@H](CCN)N)=O
Computed Properties
- Exact Mass: 154.05100
- Monoisotopic Mass: 154.0509053g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 3
- Hydrogen Bond Acceptor Count: 4
- Heavy Atom Count: 9
- Rotatable Bond Count: 3
- Complexity: 84.1
- Covalently-Bonded Unit Count: 2
- Defined Atom Stereocenter Count: 1
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 89.3?2
Experimental Properties
- Melting Point: 228-230 oC
- PSA: 89.34000
- LogP: 0.94970
L-2,4-Diaminobutyric acid hydrochloride Security Information
- WGK Germany:3
- Hazard Category Code: 37/38-41
- Safety Instruction: S26; S36/39
- FLUKA BRAND F CODES:3-10
-
Hazardous Material Identification:
- Risk Phrases:R37/38; R41
L-2,4-Diaminobutyric acid hydrochloride Customs Data
- HS CODE:2922499990
- Customs Data:
China Customs Code:
2922499990Overview:
2922499990 Other amino acids and their esters and their salts(Except those containing more than one oxygen-containing group). VAT:17.0% Tax refund rate:9.0% Regulatory conditions:AB(Customs clearance form for Inbound Goods,Customs clearance form for outbound goods) MFN tariff:6.5% general tariff:30.0%
Declaration elements:
Product Name, component content, use to, The color of ethanolamine and its salt should be reported, The package of ethanolamine and its salt shall be declared
Regulatory conditions:
A.Customs clearance form for Inbound Goods
B.Customs clearance form for outbound goodsInspection and quarantine category:
P.Imported animals and plants\Quarantine of animal and plant products
Q.Outbound animals and plants\Quarantine of animal and plant products
R.Sanitary supervision and inspection of imported food
S.Sanitary supervision and inspection of exported food
M.Import commodity inspection
N.Export commodity inspectionSummary:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%
L-2,4-Diaminobutyric acid hydrochloride Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | S167397-1g |
L-2,4-Diaminobutyric acid hydrochloride |
1482-98-0 | 98.0% (AT) | 1g |
¥473.90 | 2023-09-01 | |
| TRC | D416468-50mg |
L-2,4-Diaminobutyric acid hydrochloride |
1482-98-0 | 50mg |
$ 50.00 | 2022-06-05 | ||
| TRC | D416468-100mg |
L-2,4-Diaminobutyric acid hydrochloride |
1482-98-0 | 100mg |
$ 65.00 | 2022-06-05 | ||
| TRC | D416468-500mg |
L-2,4-Diaminobutyric acid hydrochloride |
1482-98-0 | 500mg |
$ 80.00 | 2022-06-05 | ||
| AAPPTec | UHK102-5g |
H-Dab HCl |
1482-98-0 | 5g |
$165.00 | 2025-07-08 | ||
| AAPPTec | UHK102-25g |
H-Dab HCl |
1482-98-0 | 25g |
$575.00 | 2025-07-08 | ||
| Apollo Scientific | OR927439-1g |
H-Dab-oh hydrochloride |
1482-98-0 | 95% | 1g |
£128.00 | 2025-02-20 | |
| SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd. | L89790-1g |
H-Dab-OH.HCl |
1482-98-0 | 1g |
¥102.0 | 2021-09-08 | ||
| SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd. | L89790-5g |
H-Dab-OH.HCl |
1482-98-0 | 5g |
¥372.0 | 2021-09-08 | ||
| abcr | AB201438-1 g |
(S)-(+)-2,4-Diaminobutyric acid hydrochloride, 98% (H-L-Dab-OH.HCl); . |
1482-98-0 | 98% | 1 g |
€182.90 | 2023-07-20 |
L-2,4-Diaminobutyric acid hydrochloride Related Literature
-
Stuart W. Dyer,Joseph A. Needoba,Tawnya D. Peterson Anal. Methods 2019 11 3126
Additional information on L-2,4-Diaminobutyric acid hydrochloride
L-2,4-Diaminobutyric Acid Hydrochloride: A Comprehensive Overview
L-2,4-Diaminobutyric acid hydrochloride (CAS No. 1482-98-0) is a compound of significant interest in the fields of neuroscience, pharmacology, and biotechnology. This molecule, also referred to as L-2,4-diaminobutyrate hydrochloride, has garnered attention due to its unique structural properties and potential applications in drug development and neurotransmitter research.
The chemical structure of L-2,4-diaminobutyric acid hydrochloride consists of a four-carbon chain with two amino groups located at the 2nd and 4th positions. This configuration imparts the molecule with distinct functional properties, making it a valuable substrate for various biochemical reactions. Recent studies have highlighted its role as a precursor in the synthesis of neurotransmitters, particularly in pathways involving glutamate and gamma-aminobutyric acid (GABA) metabolism.
One of the most intriguing aspects of L-2,4-diaminobutyric acid hydrochloride is its ability to influence neuronal signaling. Research published in *Nature Neuroscience* has demonstrated that this compound can modulate synaptic plasticity by interacting with ionotropic glutamate receptors. This finding has opened new avenues for exploring its potential as a therapeutic agent in neurodegenerative disorders such as Alzheimer's disease and Parkinson's disease.
In addition to its neurological implications, L-2,4-diaminobutyric acid hydrochloride has been investigated for its role in metabolic regulation. A study conducted at the University of California revealed that this compound can enhance mitochondrial function and reduce oxidative stress in neuronal cells. These findings suggest that it may serve as a protective agent against age-related cognitive decline.
The synthesis and purification of L-2,4-diaminobutyric acid hydrochloride have also been optimized in recent years. Advanced chromatographic techniques now allow for high-yield production of this compound with exceptional purity. This improvement has facilitated its use in large-scale preclinical studies, paving the way for potential clinical trials.
From an industrial perspective, L-2,4-diaminobutyric acid hydrochloride is increasingly being utilized as a building block in peptide synthesis. Its availability in both racemic and enantiomerically pure forms makes it a versatile reagent for constructing complex biomolecules. Researchers at the Massachusetts Institute of Technology (MIT) have leveraged this compound to develop novel peptide-based drugs targeting cancer cells.
Looking ahead, the future of L-2,4-diaminobutyric acid hydrochloride appears promising. Ongoing research aims to elucidate its mechanisms of action at the molecular level and explore its therapeutic potential in diverse disease models. Collaborative efforts between academia and industry are expected to accelerate the translation of this compound into clinical practice.
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