Cas no 148193-37-7 (1,2-Benzisothiazol-3(2H)-one,6-amino-)

1,2-Benzisothiazol-3(2H)-one,6-amino- is a heterocyclic compound featuring a benzisothiazolone core with an amino substituent at the 6-position. This structure imparts unique reactivity, making it valuable in pharmaceutical and agrochemical synthesis. The amino group enhances its utility as a versatile intermediate, enabling further functionalization through coupling or substitution reactions. Its benzisothiazolone scaffold is known for contributing to biological activity, particularly in antimicrobial and anti-inflammatory applications. The compound’s stability under standard conditions and compatibility with common organic solvents facilitate its use in multi-step synthetic routes. Researchers favor it for its balanced reactivity profile and potential as a building block in medicinal chemistry.
1,2-Benzisothiazol-3(2H)-one,6-amino- structure
148193-37-7 structure
Product Name:1,2-Benzisothiazol-3(2H)-one,6-amino-
CAS No:148193-37-7
MF:C7H6N2OS
MW:166.200339794159
CID:223018
PubChem ID:16206280
Update Time:2025-08-05

1,2-Benzisothiazol-3(2H)-one,6-amino- Chemical and Physical Properties

Names and Identifiers

    • 1,2-Benzisothiazol-3(2H)-one,6-amino-
    • 6-Amino-1,2-benzothiazol-3(2H)-one
    • LogP
    • AKOS026727181
    • Z1262664713
    • 148193-37-7
    • 6-Amino-1,2-benzisothiazol-3(2H)-one
    • 6-amino-2,3-dihydro-1,2-benzothiazol-3-one
    • SCHEMBL5807922
    • CCRIS 6372
    • 6-Amino-1,2-benzothiazol-3-ol
    • DTXSID10933335
    • EN300-142436
    • Inchi: 1S/C7H6N2OS/c8-4-1-2-5-6(3-4)11-9-7(5)10/h1-3H,8H2,(H,9,10)
    • InChI Key: SZAVJMSBSRKTQG-UHFFFAOYSA-N
    • SMILES: S1C2C=C(C=CC=2C(N1)=O)N

Computed Properties

  • Exact Mass: 166.02018
  • Monoisotopic Mass: 166.020084
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 0
  • Complexity: 185
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 80.4
  • XLogP3: 0.6

Experimental Properties

  • Density: 1.473
  • Refractive Index: 1.731
  • PSA: 55.12

1,2-Benzisothiazol-3(2H)-one,6-amino- Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
Enamine
EN300-142436-0.05g
6-amino-2,3-dihydro-1,2-benzothiazol-3-one
148193-37-7
0.05g
$474.0 2023-05-20
Enamine
EN300-142436-0.1g
6-amino-2,3-dihydro-1,2-benzothiazol-3-one
148193-37-7
0.1g
$619.0 2023-05-20
Enamine
EN300-142436-0.25g
6-amino-2,3-dihydro-1,2-benzothiazol-3-one
148193-37-7
0.25g
$883.0 2023-05-20
Enamine
EN300-142436-0.5g
6-amino-2,3-dihydro-1,2-benzothiazol-3-one
148193-37-7
0.5g
$1393.0 2023-05-20
Enamine
EN300-142436-1.0g
6-amino-2,3-dihydro-1,2-benzothiazol-3-one
148193-37-7
1g
$1785.0 2023-05-20
Enamine
EN300-142436-2.5g
6-amino-2,3-dihydro-1,2-benzothiazol-3-one
148193-37-7
2.5g
$3501.0 2023-05-20
Enamine
EN300-142436-5.0g
6-amino-2,3-dihydro-1,2-benzothiazol-3-one
148193-37-7
5g
$5179.0 2023-05-20
Enamine
EN300-142436-10.0g
6-amino-2,3-dihydro-1,2-benzothiazol-3-one
148193-37-7
10g
$7681.0 2023-05-20
1PlusChem
1P01ADNA-50mg
6-amino-2,3-dihydro-1,2-benzothiazol-3-one
148193-37-7 90%
50mg
$648.00 2023-12-21
1PlusChem
1P01ADNA-100mg
6-amino-2,3-dihydro-1,2-benzothiazol-3-one
148193-37-7 90%
100mg
$827.00 2023-12-21

Additional information on 1,2-Benzisothiazol-3(2H)-one,6-amino-

Compound 148193-37-7: 1,2-Benzisothiazol-3(2H)-one,6-amino

The compound with CAS No. 148193-37-7, commonly referred to as 1,2-Benzisothiazol-3(2H)-one,6-amino, is a significant molecule in the field of organic chemistry. This compound belongs to the class of benzisothiazoles, which are known for their versatile applications in drug discovery and materials science. The benzisothiazole core of this molecule provides a unique scaffold for various functional groups, making it an attractive target for researchers.

Recent studies have highlighted the potential of 1,2-Benzisothiazol-3(2H)-one,6-amino in the development of novel pharmaceutical agents. Its structure allows for easy modification at the amino group, enabling the creation of derivatives with enhanced bioactivity. For instance, researchers have explored its role as a precursor for anti-inflammatory and antioxidant agents. The amino group at position 6 is particularly important, as it can undergo various reactions to introduce bioactive substituents.

In terms of synthesis, the compound can be prepared through a variety of methods. One common approach involves the condensation of benzene thioamide with an appropriate aldehyde or ketone. This reaction typically occurs under acidic conditions and yields the benzisothiazole skeleton. The 6-amino derivative can then be obtained through selective substitution or reduction reactions. Recent advancements in catalytic methods have made this synthesis more efficient and scalable.

The applications of 148193-37-7 extend beyond pharmaceuticals. It has been investigated for its potential in materials science, particularly in the development of advanced polymers and coatings. The molecule's ability to form stable bonds with other monomers makes it a promising candidate for high-performance materials. Additionally, its photochemical properties have been studied for use in optoelectronic devices.

From a structural perspective, 1,2-Benzisothiazol-3(2H)-one exhibits a planar geometry due to the aromaticity of the benzene ring and the sulfur atom's lone pairs. This planarity contributes to its stability and reactivity. The presence of the amino group introduces additional electronic effects, which can influence both its chemical reactivity and biological activity.

Recent research has also focused on the environmental impact of this compound. Studies have shown that it exhibits low toxicity towards aquatic organisms under standard testing conditions. However, further investigations are needed to fully understand its long-term effects on ecosystems.

In conclusion, Compound 148193-37-7: 1,2-Benzisothiazol-3(2H)-one,6-amino is a versatile molecule with significant potential in multiple fields. Its unique structure and functional groups make it an ideal candidate for further research and development.

Recommended suppliers
Shandong Jing Kun Chemical Co.,Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Shandong Jing Kun Chemical Co.,Ltd.
Jinta Yudi Pharmaceutical Technology Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Jinta Yudi Pharmaceutical Technology Co., Ltd.
Suzhou Genelee Bio-Technology Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Suzhou Genelee Bio-Technology Co., Ltd.
Wuhan ChemNorm Biotech Co.,Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
Wuhan ChemNorm Biotech Co.,Ltd.
Hubei Cuiyuan Biotechnology Co.,Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
Hubei Cuiyuan Biotechnology Co.,Ltd