Cas no 148193-37-7 (1,2-Benzisothiazol-3(2H)-one,6-amino-)
1,2-Benzisothiazol-3(2H)-one,6-amino- Chemical and Physical Properties
Names and Identifiers
-
- 1,2-Benzisothiazol-3(2H)-one,6-amino-
- 6-Amino-1,2-benzothiazol-3(2H)-one
- LogP
- AKOS026727181
- Z1262664713
- 148193-37-7
- 6-Amino-1,2-benzisothiazol-3(2H)-one
- 6-amino-2,3-dihydro-1,2-benzothiazol-3-one
- SCHEMBL5807922
- CCRIS 6372
- 6-Amino-1,2-benzothiazol-3-ol
- DTXSID10933335
- EN300-142436
-
- Inchi: 1S/C7H6N2OS/c8-4-1-2-5-6(3-4)11-9-7(5)10/h1-3H,8H2,(H,9,10)
- InChI Key: SZAVJMSBSRKTQG-UHFFFAOYSA-N
- SMILES: S1C2C=C(C=CC=2C(N1)=O)N
Computed Properties
- Exact Mass: 166.02018
- Monoisotopic Mass: 166.020084
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 2
- Hydrogen Bond Acceptor Count: 3
- Heavy Atom Count: 11
- Rotatable Bond Count: 0
- Complexity: 185
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 80.4
- XLogP3: 0.6
Experimental Properties
- Density: 1.473
- Refractive Index: 1.731
- PSA: 55.12
1,2-Benzisothiazol-3(2H)-one,6-amino- Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Enamine | EN300-142436-0.05g |
6-amino-2,3-dihydro-1,2-benzothiazol-3-one |
148193-37-7 | 0.05g |
$474.0 | 2023-05-20 | ||
| Enamine | EN300-142436-0.1g |
6-amino-2,3-dihydro-1,2-benzothiazol-3-one |
148193-37-7 | 0.1g |
$619.0 | 2023-05-20 | ||
| Enamine | EN300-142436-0.25g |
6-amino-2,3-dihydro-1,2-benzothiazol-3-one |
148193-37-7 | 0.25g |
$883.0 | 2023-05-20 | ||
| Enamine | EN300-142436-0.5g |
6-amino-2,3-dihydro-1,2-benzothiazol-3-one |
148193-37-7 | 0.5g |
$1393.0 | 2023-05-20 | ||
| Enamine | EN300-142436-1.0g |
6-amino-2,3-dihydro-1,2-benzothiazol-3-one |
148193-37-7 | 1g |
$1785.0 | 2023-05-20 | ||
| Enamine | EN300-142436-2.5g |
6-amino-2,3-dihydro-1,2-benzothiazol-3-one |
148193-37-7 | 2.5g |
$3501.0 | 2023-05-20 | ||
| Enamine | EN300-142436-5.0g |
6-amino-2,3-dihydro-1,2-benzothiazol-3-one |
148193-37-7 | 5g |
$5179.0 | 2023-05-20 | ||
| Enamine | EN300-142436-10.0g |
6-amino-2,3-dihydro-1,2-benzothiazol-3-one |
148193-37-7 | 10g |
$7681.0 | 2023-05-20 | ||
| 1PlusChem | 1P01ADNA-50mg |
6-amino-2,3-dihydro-1,2-benzothiazol-3-one |
148193-37-7 | 90% | 50mg |
$648.00 | 2023-12-21 | |
| 1PlusChem | 1P01ADNA-100mg |
6-amino-2,3-dihydro-1,2-benzothiazol-3-one |
148193-37-7 | 90% | 100mg |
$827.00 | 2023-12-21 |
1,2-Benzisothiazol-3(2H)-one,6-amino- Related Literature
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Ziyang Deng,Changwei Chen,Sunliang Cui RSC Adv., 2016,6, 93753-93755
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Hanie Hashtroudi,Ian D. R. Mackinnon J. Mater. Chem. C, 2020,8, 13108-13126
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Gloria Belén Ramírez-Rodríguez,José Manuel Delgado-López,Jaime Gómez-Morales CrystEngComm, 2013,15, 2206-2212
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Ross Harder,David C. Dunand,Ian McNulty Nanoscale, 2017,9, 5686-5693
Additional information on 1,2-Benzisothiazol-3(2H)-one,6-amino-
Compound 148193-37-7: 1,2-Benzisothiazol-3(2H)-one,6-amino
The compound with CAS No. 148193-37-7, commonly referred to as 1,2-Benzisothiazol-3(2H)-one,6-amino, is a significant molecule in the field of organic chemistry. This compound belongs to the class of benzisothiazoles, which are known for their versatile applications in drug discovery and materials science. The benzisothiazole core of this molecule provides a unique scaffold for various functional groups, making it an attractive target for researchers.
Recent studies have highlighted the potential of 1,2-Benzisothiazol-3(2H)-one,6-amino in the development of novel pharmaceutical agents. Its structure allows for easy modification at the amino group, enabling the creation of derivatives with enhanced bioactivity. For instance, researchers have explored its role as a precursor for anti-inflammatory and antioxidant agents. The amino group at position 6 is particularly important, as it can undergo various reactions to introduce bioactive substituents.
In terms of synthesis, the compound can be prepared through a variety of methods. One common approach involves the condensation of benzene thioamide with an appropriate aldehyde or ketone. This reaction typically occurs under acidic conditions and yields the benzisothiazole skeleton. The 6-amino derivative can then be obtained through selective substitution or reduction reactions. Recent advancements in catalytic methods have made this synthesis more efficient and scalable.
The applications of 148193-37-7 extend beyond pharmaceuticals. It has been investigated for its potential in materials science, particularly in the development of advanced polymers and coatings. The molecule's ability to form stable bonds with other monomers makes it a promising candidate for high-performance materials. Additionally, its photochemical properties have been studied for use in optoelectronic devices.
From a structural perspective, 1,2-Benzisothiazol-3(2H)-one exhibits a planar geometry due to the aromaticity of the benzene ring and the sulfur atom's lone pairs. This planarity contributes to its stability and reactivity. The presence of the amino group introduces additional electronic effects, which can influence both its chemical reactivity and biological activity.
Recent research has also focused on the environmental impact of this compound. Studies have shown that it exhibits low toxicity towards aquatic organisms under standard testing conditions. However, further investigations are needed to fully understand its long-term effects on ecosystems.
In conclusion, Compound 148193-37-7: 1,2-Benzisothiazol-3(2H)-one,6-amino is a versatile molecule with significant potential in multiple fields. Its unique structure and functional groups make it an ideal candidate for further research and development.
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