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• Solvents and Organic Chemicals Organic Compounds Benzenoids Phenol ethers Anisoles
• Solvents and Organic Chemicals Organic Compounds Alcohol/Ether

4-Bromo-2,6-Dimethylanisole (CAS No. 14804-38-7): An Overview of Its Properties, Applications, and Recent Research

4-Bromo-2,6-dimethylanisole (CAS No. 14804-38-7) is a versatile organic compound that has gained significant attention in the fields of chemistry, pharmaceuticals, and materials science. This compound is characterized by its unique molecular structure, which includes a bromine atom and two methyl groups attached to an anisole ring. The combination of these functional groups imparts distinct chemical and physical properties that make it a valuable intermediate in various synthetic processes.

The chemical formula of 4-Bromo-2,6-dimethylanisole is C₉H₁₁OBr, and its molecular weight is approximately 209.09 g/mol. The compound is a colorless to pale yellow liquid at room temperature and has a characteristic aromatic odor. It is soluble in common organic solvents such as ethanol, acetone, and dichloromethane but has limited solubility in water.

In the realm of synthetic chemistry, 4-Bromo-2,6-dimethylanisole serves as a crucial building block for the synthesis of more complex molecules. Its bromine functionality makes it an excellent substrate for various cross-coupling reactions, such as Suzuki-Miyaura coupling and Stille coupling. These reactions are widely used in the synthesis of pharmaceuticals, agrochemicals, and advanced materials. For instance, recent studies have demonstrated the use of 4-Bromo-2,6-dimethylanisole in the synthesis of novel antifungal agents and anti-inflammatory compounds.

The pharmaceutical industry has shown particular interest in 4-Bromo-2,6-dimethylanisole due to its potential applications in drug discovery and development. Researchers have explored its role as a precursor for the synthesis of bioactive molecules with therapeutic potential. One notable example is its use in the development of selective serotonin reuptake inhibitors (SSRIs), which are widely prescribed for the treatment of depression and anxiety disorders. The bromine atom in 4-Bromo-2,6-dimethylanisole can be selectively replaced with other functional groups to fine-tune the pharmacological properties of the final product.

Beyond its applications in pharmaceuticals, 4-Bromo-2,6-dimethylanisole has also found use in materials science. Its unique electronic properties make it suitable for the synthesis of organic semiconductors and conductive polymers. These materials are essential components in modern electronic devices such as organic light-emitting diodes (OLEDs) and organic photovoltaic cells (OPVs). Recent advancements in this field have led to the development of more efficient and cost-effective organic electronic devices using derivatives of 4-Bromo-2,6-dimethylanisole.

In addition to its synthetic utility, 4-Bromo-2,6-dimethylanisole has been studied for its environmental impact and safety profile. Researchers have investigated its biodegradability and potential toxicity to ensure that it can be used safely in industrial processes. Studies have shown that under controlled conditions, 4-Bromo-2,6-dimethylanisole can be effectively degraded by microbial action, reducing its environmental persistence.

The safety data sheet (SDS) for 4-Bromo-2,6-dimethylanisole provides comprehensive information on its handling and storage requirements. It is recommended to store the compound in a cool, dry place away from incompatible substances such as strong oxidizers and strong acids. Personal protective equipment (PPE) should be worn when handling this compound to minimize exposure risks.

In conclusion, 4-Bromo-2,6-dimethylanisole (CAS No. 14804-38-7) is a multifaceted compound with a wide range of applications in chemistry, pharmaceuticals, and materials science. Its unique chemical structure and versatile reactivity make it an indispensable intermediate in various synthetic processes. Ongoing research continues to uncover new applications and improve our understanding of this important compound.

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