• 1. Excellent electrochemical performance of LiFe0.4Mn0.6PO4 microspheres produced using a double carbon coating process?
  Yong Ping Huang,Tao Tao,Zheng Chen,Wei Han,Ying Wu,Chunjiang Kuang,Shaoxiong Zhou,Ying Chen J. Mater. Chem. A, 2014,2, 18831-18837
• 2. Excellent peroxidase mimicking property of CuO/Pt nanocomposites and their application as an ascorbic acid sensor?
  Xinhuan Wang,Shuangfei Cai,Cui Qi Analyst, 2017,142, 2500-2506
• 3. Examination of ammonia–poly(pyrrole) interactions by piezoelectric and conductivity measurements
  Analyst, 1991,116, 1125-1130
• 4. Excitable dynamics in the bromate–sulfite–ferrocyanide reaction
  J. Zagora,M. Vosla?,L. Schreiberová,I. Schreiber Phys. Chem. Chem. Phys., 2002,4, 1284-1291
• 5. Fast synthesis of red Li3BaSrLn3(WO4)8:Eu3+ phosphors for white LEDs under near-UV excitation by a microwave-assisted solid state reaction method and photoluminescence studies
  Bo Wei,Zhenyu Liu,Chen Xie,Shu Yang,Wentao Tang,Aiwei Gu,Wing-Tak Wong,Ka-Leung Wong J. Mater. Chem. C, 2015,3, 12322-12327

• Solvents and Organic Chemicals Organic Compounds Organic acids and derivatives Carboxylic acids and derivatives Amino acids, peptides, and analogues Amino acids and derivatives

Exploring (R)-Homobenzyl-β-alanine (CAS 147228-37-3): Properties, Applications, and Market Insights

(R)-Homobenzyl-β-alanine (CAS 147228-37-3) is a specialized chiral amino acid derivative that has garnered significant attention in pharmaceutical and biochemical research. This compound, characterized by its unique homobenzyl substitution and β-alanine backbone, serves as a critical building block in the synthesis of bioactive molecules. Its enantiomeric purity and structural versatility make it invaluable for drug development, particularly in targeting G-protein-coupled receptors (GPCRs) and enzyme modulation.

The growing demand for chiral intermediates like (R)-Homobenzyl-β-alanine aligns with trends in precision medicine and personalized therapeutics. Researchers are increasingly focusing on enantioselective synthesis to improve drug efficacy and reduce side effects. This compound’s role in peptide-based drug design is particularly noteworthy, as it enhances stability and bioavailability—a hot topic in biopharmaceutical innovation.

From a chemical perspective, (R)-Homobenzyl-β-alanine exhibits remarkable stereochemical stability, which is crucial for maintaining activity in biological systems. Its carboxyl and amino functional groups allow for seamless integration into larger molecular frameworks, enabling applications in cancer therapeutics, neurological disorders, and metabolic disease research. Recent studies highlight its potential in prodrug formulations, addressing challenges like poor membrane permeability.

The market for (R)-Homobenzyl-β-alanine is expanding, driven by advancements in asymmetric catalysis and green chemistry. Manufacturers are adopting continuous flow processes to scale up production sustainably—a response to the pharmaceutical industry’s push for eco-friendly synthesis. Analytical techniques such as HPLC chiral separation and NMR spectroscopy ensure the compound’s high purity, meeting stringent regulatory standards for GMP-grade materials.

In the context of AI-driven drug discovery, (R)-Homobenzyl-β-alanine is frequently explored in virtual screening libraries. Computational models predict its interactions with targets like ion channels and kinases, accelerating lead optimization. This synergy between computational chemistry and experimental validation underscores its relevance in modern high-throughput screening platforms.

For researchers sourcing (R)-Homobenzyl-β-alanine, key considerations include storage conditions (typically -20°C under inert gas) and solubility profiles (compatible with DMSO and aqueous buffers). Suppliers often provide certificates of analysis (CoA) detailing enantiomeric excess (ee) ≥99%, a critical parameter for reproducibility in structure-activity relationship (SAR) studies.

Looking ahead, the compound’s adaptability in bioconjugation and proteolysis-targeting chimera (PROTAC) design positions it at the forefront of next-generation therapeutics. As the scientific community prioritizes targeted protein degradation and allosteric modulation, (R)-Homobenzyl-β-alanine is poised to play a pivotal role in addressing unmet medical needs.

• 26250-87-3((S)-3-Amino-4-phenylbutanoic acid)
• 15099-85-1(3-Amino-4-phenylbutanoic acid)
• 131270-08-1((R)-3-Amino-4-phenylbutanoic acid)
• 916198-97-5((4S)-4-amino-5-phenyl-pentanoic acid)
• 91247-38-0(3-Amino-5-phenylpentanoic acid)
• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)