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Comprehensive Overview of 5-Amino-1-(2-chlorophenyl)-1H-pyrazole-4-carboxylic acid (CAS No. 14678-89-8)

5-Amino-1-(2-chlorophenyl)-1H-pyrazole-4-carboxylic acid (CAS No. 14678-89-8) is a specialized organic compound that has garnered significant attention in pharmaceutical and agrochemical research. This heterocyclic molecule, featuring a pyrazole core, is widely studied for its potential applications in drug discovery and material science. The presence of both amino and carboxylic acid functional groups makes it a versatile intermediate for synthesizing more complex molecules.

In recent years, the demand for pyrazole derivatives has surged due to their broad biological activities, including anti-inflammatory, antimicrobial, and anticancer properties. Researchers are particularly interested in 5-Amino-1-(2-chlorophenyl)-1H-pyrazole-4-carboxylic acid as a precursor for designing novel therapeutics. Its 2-chlorophenyl substituent enhances lipophilicity, which can improve membrane permeability—a critical factor in drug development.

The compound’s CAS No. 14678-89-8 is frequently searched in academic databases and chemical marketplaces, reflecting its industrial relevance. With the rise of AI-driven drug discovery, this molecule is often highlighted in computational studies for its binding affinity to various biological targets. Additionally, its structural features align with the growing trend of green chemistry, as researchers explore eco-friendly synthesis routes to minimize waste and energy consumption.

One of the most common questions about 5-Amino-1-(2-chlorophenyl)-1H-pyrazole-4-carboxylic acid revolves around its solubility and stability under different conditions. Studies indicate that the carboxylic acid group allows for easy salt formation, enhancing its applicability in formulation development. Furthermore, the amino group offers opportunities for further functionalization, making it a valuable building block in medicinal chemistry.

From an industrial perspective, suppliers of CAS No. 14678-89-8 emphasize its high purity and compliance with regulatory standards. The compound is typically characterized using advanced techniques like NMR spectroscopy and HPLC, ensuring quality control for end-users. As the pharmaceutical industry shifts toward personalized medicine, intermediates like this pyrazole derivative are gaining traction for their role in creating targeted therapies.

In summary, 5-Amino-1-(2-chlorophenyl)-1H-pyrazole-4-carboxylic acid represents a critical intersection of chemistry and life sciences. Its unique structure and functional groups position it as a key player in the development of next-generation therapeutics and agrochemicals. As research continues to uncover its full potential, this compound is poised to remain a focal point in scientific and industrial discussions.

• 14678-86-5(Ethyl 5-amino-1-(2-chlorophenyl)-1H-pyrazole-4-carboxylate)
• 14678-90-1(5-Amino-1-(4-chlorophenyl)-1H-pyrazole-4-carboxylic acid)
• 15070-84-5(5-Amino-1-(3-chlorophenyl)-1H-pyrazole-4-carboxylic Acid)
• 83279-66-7(Ethyl 5-amino-1-(2,4-dichlorophenyl)-1H-pyrazole-4-carboxylate)
• 14678-87-6(Ethyl 5-amino-1-(4-chlorophenyl)-1H-pyrazole-4-carboxylate)
• 51649-80-0(5-Amino-1-phenyl-1H-pyrazole-4-carboxylic acid)
• 1253791-51-3(Ethyl 5-amino-1-(2-chlorophenyl)-1H-pyrazole-4-carboxylate hydrochloride)
• 1225550-72-0(5-Amino-1-(2,3-dichlorophenyl)-1H-Pyrazole-4-carboxylic acid)
• 15001-08-8(Ethyl 5-amino-1-(3-chlorophenyl)-1H-pyrazole-4-carboxylate)
• 77746-66-8(1H-Pyrazole-4-carboxaldehyde, 5-amino-1-(4-chlorophenyl)-)