Cas no 146504-07-6 (tert-butyl N-[(1R,2R)-2-aminocyclohexyl]carbamate)

tert-butyl N-[(1R,2R)-2-aminocyclohexyl]carbamate structure
146504-07-6 structure
Product Name:tert-butyl N-[(1R,2R)-2-aminocyclohexyl]carbamate
CAS No:146504-07-6
MF:C11H22N2O2
MW:214.304583072662
MDL:MFCD08726023
CID:105477
PubChem ID:1514390
Update Time:2025-11-02

tert-butyl N-[(1R,2R)-2-aminocyclohexyl]carbamate Chemical and Physical Properties

Names and Identifiers

    • Carbamic acid,N-[(1R,2R)-2-aminocyclohexyl]-, 1,1-dimethylethyl ester
    • (1R,2R)-trans-N-Boc-1,2-cyclohexanediamine
    • N-Boc-1R,2R-Cyclohexanediamine
    • tert-Butyl (trans-2-aminocyclohexyl)carbamate
    • tert-Butyl ((1R,2R)-2-aminocyclohexyl)carbamate
    • (1R,2R)-2-Amino-1-(Boc-amino)cyclohexane
    • (1R,2R)-2-Amino-1-(tert-butoxycarbonylamino)cyclohexane
    • [(1R,2R)-2-Aminocyclohexyl]carbamic Acid tert-Butyl Ester
    • (1R,2R)-N1-Boc-1,2-cyclohexanediamine
    • tert-Butyl [(1R,2R)-2-Aminocyclohexyl]carbamate
    • ((1R,2R)-2-Aminocyclohexyl)-carbamic acid tert-butyl ester
    • (1R,2R)-(-)-N-(t-Butoxycarbonyl)-1,2-cyclohexanediamine
    • (1R,2R)-N-tert.-Butoxycarbonylcyclohexane-1,2-diamine
    • N-tert-Butoxycarbonyl-R,R-1,2-diaminocyclohexane
    • tert-Butyl N-((1R,2R)-2-aminocyclohexyl)carbamate
    • (1R,2R)-N-Boc-1,2-cyclohexanediamine
    • (1R)-trans-N-Boc-1,2-diaminocyclohexane
    • (1R,2R)-1-AMINO-2-(BOC-AMINO)-CYCLOHEXANE
    • Trans (1R,2R)-1N-Boc-cyclohexane-1,2-diamine
    • N-Boc-trans-1,2-diaminocyclohexane
    • trans-N-Boc-1,2-diaminocyclohexane
    • tert-butyl (1R,2R)-2-aminocyclohexylcarbamate
    • tert-butyl N-[(1R,2R)-2-aminocyclohexyl]carbamate
    • (1R,2R)-Boc-1,2-diaminocyclohexane
    • 1-n-boc-1,2-trans-cyclohexyldiamine
    • Carbamic acid, (
    • 146504-07-6
    • N-Boc-trans-1,2-damnocyclohexane
    • 1-n-boc-1(r), 2(r)-cyclohexyldiamine
    • rac-tert-butyl N-[(1R,2R)-2-aminocyclohexyl]carbamate
    • s3896
    • CS-D0336
    • 137731-41-0
    • J-523520
    • trans-N1-Boc-cyclohexane-1,2-diamine
    • A2968
    • (1R,2R)-1-(Boc-amino)cyclohexan-2-amine
    • trans-(2-aminocyclohexyl)-carbamic acid tert-butyl ester
    • F8887-8832
    • B5647
    • CCG-266681
    • Z558512334
    • HY-33292
    • SCHEMBL1045289
    • J-007053
    • trans-1-Amino-2-((tert-butoxycarbonyl)amino)cyclohexane
    • DS-7843
    • ((1R,2R)-2-Amino-cyclohexyl)-carbamic acid tert-butyl ester
    • (+/-)-trans-N-tert-butoxycarbonyl-1,2-cyclohexanediamine
    • AKVIZYGPJIWKOS-RKDXNWHRSA-N
    • N-Boc-trans-1,2-diaminocyclohexane, AldrichCPR
    • AMY24032
    • EN300-258219
    • tert-Butyl trans-2-aminocyclohexylcarbamate
    • n-boc-trans-1,2-cyclohexanediamine
    • 1-n-boc-1(r),2(r)-cyclohexyldiamine
    • Carbamic acid, N-?[(1R,?2R)?-?2-?aminocyclohexyl]?-?, 1,?1-?dimethylethyl ester
    • AKOS015854135
    • MFCD08726023
    • EN300-45538
    • trans-(2-amino-cyclohexyl)-carbamic acid tert-butyl ester
    • trans,1n-boc-cyclohexane-1,2-diamine
    • (1R,2R)-trans-N-Boc-1,2-cyclohexanediamine, 97%
    • DTXSID00929883
    • (1R,2R)-N1-(tert-Butoxycarbonyl)-1,2-cyclohexanediamine
    • CHEBI:192567
    • Carbamic acid, (2-aminocyclohexyl)-, 1,1-dimethylethyl ester, trans-
    • (1R,2R)-N-(tert-Butoxycarbonylamino]cyclohexane
    • 1,1-Dimethylethyl (trans-2-aminocyclohexyl)carbamate
    • N-(t-butoxycarbonyl)-trans-1,2-diaminocyclohexane
    • MFCD06795909
    • TRANS-1-AMINO-2-(BOC-AMINO)-CYCLOHEXANE
    • trans-n-boc-1,2-cyclohexanediamine
    • (+/-)-trans-N-tert-Butoxycarbonyl-1,2-cyclohexane-diamine
    • A3198
    • carbamic acid, n-[(1r,2r)-2-aminocyclohexyl]-, 1,1-dimethylethyl ester, rel-
    • tert-Butyl hydrogen (2-aminocyclohexyl)carbonimidate
    • DB-007750
    • MDL： MFCD08726023
    • Inchi： 1S/C11H22N2O2/c1-11(2,3)15-10(14)13-9-7-5-4-6-8(9)12/h8-9H,4-7,12H2,1-3H3,(H,13,14)/t8-,9-/m1/s1
    • InChI Key： AKVIZYGPJIWKOS-RKDXNWHRSA-N
    • SMILES： O(C(C)(C)C)C(N[C@@H]1CCCC[C@H]1N)=O

Computed Properties

  • Exact Mass: 214.16826
  • Monoisotopic Mass: 214.168
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 15
  • Rotatable Bond Count: 3
  • Complexity: 223
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 2
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 64.4
  • XLogP3: 1.3

Experimental Properties

  • Density: 1.02±0.1 g/cm3 (20 oC 760 Torr),
  • Melting Point: 114.0 to 118.0 deg-C
  • Boiling Point: 322.1°C at 760 mmHg
  • Flash Point: 148.6 °C
  • Refractive Index: 1.488
  • Solubility: Slightly soluble (5.4 g/l) (25 o C),
  • PSA: 64.35
  • LogP: 2.87220
  • Optical Activity: [α]/D -26±2°, c =?1 in chloroform

tert-butyl N-[(1R,2R)-2-aminocyclohexyl]carbamate Security Information

tert-butyl N-[(1R,2R)-2-aminocyclohexyl]carbamate Pricemore >>

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abcr
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(1R,2R)-N-(tert-Butoxycarbonylamino]cyclohexane; .
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tert-butyl N-[(1R,2R)-2-aminocyclohexyl]carbamate Suppliers

Amadis Chemical Company Limited
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(CAS:146504-07-6)tert-butyl N-[(1R,2R)-2-aminocyclohexyl]carbamate
Order Number:A3198
Stock Status:in Stock
Quantity:25g
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 04:23
Price ($):260.0

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Additional information on tert-butyl N-[(1R,2R)-2-aminocyclohexyl]carbamate

tert-butyl N-[(1R,2R)-2-aminocyclohexyl]carbamate (CAS No. 146504-07-6): A Comprehensive Overview

In the realm of organic chemistry and pharmaceutical research, tert-butyl N-[(1R,2R)-2-aminocyclohexyl]carbamate (CAS No. 146504-07-6) stands out as a pivotal compound. This chiral building block is widely utilized in the synthesis of bioactive molecules, particularly in the development of peptide mimetics and small-molecule drugs. Its unique structural features, including the tert-butyl carbamate protecting group and the (1R,2R)-2-aminocyclohexyl backbone, make it a versatile intermediate for asymmetric synthesis and medicinal chemistry applications.

The growing interest in chiral amines and cyclohexyl derivatives has propelled the demand for tert-butyl N-[(1R,2R)-2-aminocyclohexyl]carbamate. Researchers frequently search for its synthetic routes, spectroscopic data, and applications in drug discovery. With the rise of AI-driven drug design and high-throughput screening, this compound has gained traction as a key scaffold for optimizing pharmacokinetic properties and target selectivity.

One of the most common queries related to CAS No. 146504-07-6 revolves around its stereochemical purity and enantiomeric excess. Given the importance of chirality in drug efficacy, manufacturers and researchers prioritize high-purity grades of this compound. Advanced analytical techniques such as HPLC and NMR spectroscopy are employed to ensure its optical purity, a critical factor in regulatory submissions for preclinical studies.

Another hot topic linked to tert-butyl N-[(1R,2R)-2-aminocyclohexyl]carbamate is its role in green chemistry initiatives. As the pharmaceutical industry shifts toward sustainable practices, researchers explore catalyst-free synthesis and solvent-free reactions to produce this intermediate. These efforts align with global trends like carbon footprint reduction and waste minimization, making the compound a subject of interest in environmentally friendly synthesis.

From a commercial perspective, CAS No. 146504-07-6 is often sourced for custom synthesis projects. Companies specializing in fine chemicals and contract research highlight its availability in bulk quantities, catering to the needs of pharmaceutical developers and academic laboratories. Its stability under standard storage conditions further enhances its appeal for long-term research programs.

In summary, tert-butyl N-[(1R,2R)-2-aminocyclohexyl]carbamate (CAS No. 146504-07-6) is a cornerstone in modern synthetic chemistry. Its applications span drug discovery, chiral auxiliaries, and sustainable synthesis, addressing both scientific and industrial demands. As research continues to evolve, this compound will undoubtedly remain a focal point for innovation in organic and medicinal chemistry.

146504-07-6 (tert-butyl N-[(1R,2R)-2-aminocyclohexyl]carbamate) Related Products

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Amadis Chemical Company Limited
(CAS:146504-07-6)tert-butyl N-[(1R,2R)-2-aminocyclohexyl]carbamate
A3198
Purity:99%
Quantity:25g
Price ($):260.0
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